Publications by authors named "Li-Juan Liao"

Article Synopsis
  • Recent research highlights the link between a specific bacterial strain and diseases like gastric sinusitis, peptic ulcers, and gastric adenocarcinoma, emphasizing the urgent need for new antibiotics due to severe drug resistance.
  • Among nine compounds tested, deoxyshikonin showed the highest antibacterial efficacy with a minimum inhibitory concentration (MIC) of 0.5-1 µg/mL, working well in acidic environments and exhibiting low chances of resistance.
  • In mouse studies, deoxyshikonin significantly improved acute gastritis, reducing bacterial colonization and gastric damage more effectively than standard treatments, indicating its potential as a new therapeutic option against drug-resistant infections.
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Ethnopharmacological Relevance: Cinnamomum cassia Presl (Cinnamomum cassia) is a common traditional Chinese medicine, which can promote the secretion and digestion of gastric juice, improve the function of gastrointestinal tract. Cinnamaldehyde (CA) is a synthetic food flavoring in the Chinese Pharmacopoeia.

Aim Of The Study: This study aimed to search for the active ingredient (CA) of inhibiting H.

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Background: Resistance to antibiotics is one the main factors constraining the treatment and control of () infections. Therefore, there is an urgent need to develop new antimicrobial agents to replace antibiotics. Our previous study found that linolenic acid-metronidazole (Lla-Met) has a good antibacterial effect against both antibiotic-resistant and sensitive .

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Modifying and transforming natural antibacterial products is a novel idea for developing new efficacious compounds. Phillygenin has an inhibitory effect on . The aim of the present study was to prepare a phillygenin derivative (PHI-Der) through demethylation and hydroxylation.

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Background: () is the main pathogen that causes a variety of upper digestive diseases. The drug resistance rate of is increasingly higher, and the eradication rate is increasingly lower. The antimicrobial resistance of is an urgent global problem.

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With the widespread use and abuse of antibiotics, () has become seriously drug resistant. The development of new antibiotics is an important way to solve 's drug resistance. Screening antibacterial ingredients from natural products is a convenient way to develop new antibiotics.

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Background: Legionellosis remains a public health problem. The most common diagnostic method to detect Legionella pneumophila (L. pneumophila) is culture.

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Based on previous studies, we found that Bacillus Calmette-Guérin (BCG) vaccination may play a role in preventing SARS-CoV-2 infection. Therefore, we conducted a meta-analysis to investigate this protective effect. We searched the Embase, PubMed, Web of Science, Cochrane Library, BioRxiv, and MedRxiv databases for studies that evaluated the relationship between BCG vaccination and SARS-CoV-2 infection or COVID-19 disease.

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The production of ε-poly-L: -lysine (ε-PL) by Streptomyces sp. M-Z18 from glycerol was investigated in a 5-L jar-fermenter. Batch fermentations by Streptomyces sp.

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