[Effects of different drying methods on ginsenosides based on UHPLC-Q-Exactive Orbitrap MS technique].

The present study quickly identified the ginsenosides in fresh Panax ginseng and specified the effects of different drying methods(50 ℃-drying, 80 ℃-drying, and-70 ℃ freeze-drying) on ginsenosides.Three P.ginseng products by different drying methods were prepared, and the UHPLC-Q-Exactive Orbitrap high-resolution liquid mass spectrometry(MS) technique was applied to perform gradient elution using water-acetonitrile as the mobile phase, and the data collected in the negative ion mode were analyzed using X Calibur 2.

Synthesis and insecticidal activities of 4-(propargyloxy) benzenesulfonamide derivatives.

A series of 4-(propargyloxy) benzenesulfonamide derivatives with different substituents on the benzene ring were synthesized and evaluated for their insecticidal activity. Some of the compounds showed good insecticidal activity against , and the LC value of the most active compound was 0.235 mg/ml.

Fluorescence detection of malachite green and cations (Cr, Fe and Cu) by a europium-based coordination polymer.

Due to remarkable fluorescence characteristics, lanthanide coordination polymers (CP) have been widely employed in fluorescence detection, but it is rarely reported that they act as multifunctional luminescent probes dedicated to detecting malachite green (MG) and various metal ions. A europium-based CP fluorescent probe, Eu(PDCA)(HO) (PDCA = 2,6-pyridinedicarboxylic acid), has been synthesized and exhibited excellent recognition ability for malachite green and metal cations (Cr, Fe and Cu) among 11 metal cations, 13 anions and six other compounds. The recognition was achieved by fluorescence quenching when MG, Cr, Fe and Cu were added to a suspension of Eu(PDCA)(HO) respectively.

Design, synthesis, and insecticidal activities of propargyloxy-naphthalene-sulfonamide derivatives.

In our previous studies, a kind of novel benzenesulfonamides was found to be a candidate insecticidal compounds. It was shown that propargyloxy and sulfonamide groups are pharmacodynamic groups. One hundred and twenty-six (126) naphthalenesulfonamides derivatives with propargyloxy functionality were designed and synthesized, and their insecticidal activities were determined.

Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and male infertility risk: An updated meta-analysis.

Background: 18 previous meta-analyses have been published on the methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms with male infertility risk. However, results of the previous meta-analyses were still inconsistent. Moreover, their meta-analyses did not assess false-positive report probabilities except one study.

Photocatalytic Activity Investigation of α-Zirconium Phosphate Nanoparticles Compositing with CN under Ultraviolet Light.

In order to further develop efficient ultraviolet light-driven photocatalysts for environmental application, α-zirconium phosphate (α-ZrP) and carbon nitride (CN) were synthesized, respectively. Then, CN-ZrP compositing nanomaterials were prepared by compositing α-ZrP nanocrystals and CN with different mass ratios. CN-ZrP compositing nanomaterials were characterized by X-ray diffraction, scanning electron microscopy, Fourier transform infrared spectroscopy, and X-ray photoelectron spectroscopy.

A Europium-based MOF Fluorescent Probe for Efficiently Detecting Malachite Green and Uric Acid.

Lanthanide (such as Tb and Eu) metal-organic frameworks (MOFs) have been widely used in fluorescent probes because of their multiple coordination modes and brilliant fluorescence characteristic. Many lanthanide MOFs were applied in detecting metal ions, inorganic anions, and small molecules. However, it's rarely reported that Ln-MOF was devoted to detecting malachite green (MG) and uric acid (UA).

Experimental Investigation of Hydrophobically Modified α-ZrP Nanosheets for Enhancing Oil Recovery in Low-Permeability Sandstone Cores.

Highly crystalline α-zirconium phosphate (α-ZrP) nanoparticles were synthesized and exfoliated into nanosheets, and then the hydrophilic nanosheets were modified into hydrophobic nanosheets with octadecyltrichlorosilane (OTS). Scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction, and thermogravimetric analysis were applied to confirm the morphology and chemical structure of the nanosheets. Contact angle measurement was conducted to explore the wettability alteration of the hydrophobically modified α-ZrP nanosheets, and the result showed that the wettability of the core was changed into hydrophobicity.

dl-3-n-butylphthalide preserves white matter integrity and alleviates cognitive impairment in mice with chronic cerebral hypoperfusion.

Aims: Effects of dl-3-n-butylphthalide (NBP) on white matter damage and cognitive impairment in vascular cognitive impairment (VCI) have not been well studied. This study aimed to investigate the effects of NBP treatment on chronic cerebral hypoperfusion-induced white matter lesions and cognitive dysfunction in mice.

Methods: Mice were subjected to bilateral common carotid artery stenosis (BCAS) for over 30 days.

Effective adsorption of Congo red by a MOF-based magnetic material.

Metal-organic frameworks (MOFs) are an exciting class of porous crystallized materials, which have attracted great interest in sustainable energy and environmental remediation. Magnetite (Fe3O4) is one of the best-known magnetic materials and has been extensively studied with respect to properties involving high saturation magnetization, biocompatibility and low toxicity. The combination of MOFs and Fe3O4 has shown its potential applications in drug delivery, catalysis and wastewater treatment.

Three Cd(II) MOFs with Different Functional Groups: Selective CO Capture and Metal Ions Detection.

Three Cd(II) iso-frameworks {[Cd(BIPA)(IPA)]·DMF} (1), {[Cd(BIPA)(HIPA)]·DMF} (2), and {[Cd(BIPA)(NIPA)]·2HO} (3) were synthesized from the self-assembly of the BIPA ligand (BIPA = bis(4-(1 H-imidazol-1-yl)phenyl)amine) and different carboxylic ligands (HIPA = isophthalic acid, HHIPA = 5-hydroxyisophthalic acid, HNIPA = 5-nitroisophthalic acid) with Cd(II), which have amino groups, amino and phenolic hydroxyl groups, and amino and nitro groups, respectively. Both 1 and 2 exhibit CO uptakes of more than 20 wt %, indicating that amino and phenolic hydroxyl functionalized groups are beneficial to CO adsorption. Their applications and mechanisms in detecting metal ions were researched.

A Highly Solvent-Stable Metal-Organic Framework Nanosheet: Morphology Control, Exfoliation, and Luminescent Property.

Compared to bulk metal-organic framework (MOF), 2D MOF nanosheets have gained intensive research attention due to their ultrathin thickness and large surface area with highly accessible active sites. However, structural deterioration and morphological damage have impeded producing high-quality MOF nanosheets during exfoliation. Here, first a new layered bulk MOF ZSB-1 is synthesized and several solvents such as isopropanol, methanol, n-hexyl alcohol, and N,N-dimethylformamide are surveyed to examine their performance for the exfoliation of layered ZSB-1.

Three Zn(ii)-based MOFs for luminescence sensing of Fe and CrO ions.

Three zinc metal-organic frameworks (MOFs), {ZnL(chd)} (1), {[Zn(L)(oba)]·DMF·HO} (2) and {[Zn(L)(sdb)]·HO} (3) [L = E,E-2,5-dihexyloxy-1,4-bis-(2-pyridin-vinyl)-benzene; Hchd = 1,4-cyclohexanedicarboxylic acid, Hoba = 4,4'-oxybisbenzoic acid, Hsdb = 4,4'-sulfonyldibenzoic acid], have been hydrothermally synthesized. We explored their applications in detecting ions, and the result shows that they all show highly selective sensing for Fe and CrO ions.

Two cadmium(II) fluorous coordination compounds tuned by different bipyridines.

Fluorine is the most electronegative element and can be used as an excellent hydrogen-bond acceptor. Fluorous coordination compounds exhibit several advantageous properties, such as enhanced high thermal and oxidative stability, low polarity, weak intermolecular interactions and a small surface tension compared to hydrocarbons. C-H.

Exploring the Detection of Metal Ions by Tailoring the Coordination Mode of V-Shaped Thienylpyridyl Ligand in Three MOFs.

By employing a rational design approach, we synthesized three luminescent metal-organic frameworks (MOFs) 1-3 affording different coordination modes of V-shaped thienylpyridyl ligand. Their application in detecting metal ions was explored, and the mechanism was inferred. And the result exhibits that MOF 3 is a dual-responsive luminescent probe for Fe and Al ions.

A new five-coordinated copper compound for efficient degradation of methyl orange and Congo red in the absence of UV-visible radiation.

A new copper-based coordination compound Cu(2,2'-bipy)(pfbz) (1) (where 2,2'-bipy = 2,2'-bipyridine; pfbz = pentafluorobenzoate), was hydrothermally synthesized and structurally characterized. Compound 1 having a binuclear structure consists of two copper cations and two oxygen atoms alternately in a plane square arrangement. In the presence of very small amounts of HO, the catalytic properties of compound 1 for the degradation of methyl orange (MO) are excellent in the absence of UV-visible radiation.

Three Highly Stable Cobalt MOFs Based on "Y"-Shaped Carboxylic Acid: Synthesis and Absorption of Anionic Dyes.

Three Co(II) metal-organic frameworks (MOFs) were synthesized employing a rational design approach. On the basis of the different structures of three complexes, we tested their absorption properties toward two anionic dyes. The absorption results indicate that not only uncoordinated functional groups in the structure play an important role in adsorbing capacity but also physical forces can affect absorbing ability.

The complete mitochondrial genome of Astatotilapia burtoni.

Astatotilapia burtoni is a species of fish in the Cichlidae family. Astatotilapia burtoni has been used as a model organism to research the behaviors and physical systems of cichlids. Here, we reported the complete mitogenome sequence of A.

Malibatol A regulates microglia M1/M2 polarization in experimental stroke in a PPARγ-dependent manner.

Background: Activation of microglia plays a crucial role in immune and inflammatory processes after ischemic stroke. Microglia is reported with two opposing activated phenotypes, namely, classic phenotype (M1) and the alternative phenotype (M2). Inhibiting M1 while stimulating M2 has been suggested as a potential therapeutic approach in the treatment of stroke.

Poly[(μ-pentafluorobenzoato-κ²O:O')(pentafluorobenzoato-κO)(μ-pyrazine-κ²N:N')copper(II)]: a coordination polymer linked into a three-dimensional network by intermolecular C-H···F-C interactions.

In the title compound, [Cu(C6F5COO)2(C4H4N2)]n, (I), the asymmetric unit contains one Cu(II) cation, two anionic pentafluorobenzoate ligands and one pyrazine ligand. Each Cu(II) centre is five-coordinated by three O atoms from three independent pentafluorobenzoate anions, as well as by two N atoms from two pyrazine ligands, giving rise to an approximately square-pyramidal coordination geometry. Adjacent Cu(II) cations are bridged by a pyrazine ligand and two pentafluorobenzoate anions to give a two-dimensional layer.

Fotemustine, teniposide and dexamethasone in treating patients with CNS lymphoma.

Purpose: We developed and evaluated a regimen including fotemustine, teniposide and dexamethasone (FTD) for treating patients with central nervous system (CNS) lymphoma based on pharmacokinetic properties of individual agents and in combination.

Patients And Methods: In a comparison study, 8 patients with primary CNS lymphoma (PCNSL) and 8 with secondary CNS lymphoma (SCNSL) were treated with FTD (comprising fotemustine 100 mg/m2, 1h infusion, day 1; teniposide 60 mg/m2, >0.5 h infusion, on day 2, 3, 4; dexamethasone 40 mg, 1h infusion, on day 1, 2, 3, 4 and 5; and methotrexate 12 mg, cytosine arabinoside 50 mg plus dexamethasone 5 mg intrathecally, on day 2 and 7).

Speciation of inorganic selenium in environmental water samples by inductively coupled plasma optical emission spectrometry after preconcentration by using a mesoporous zirconia coating on coal cinder.

A simple, novel, and selective flow-injection solid-phase extraction with inductively coupled plasma optical emission spectrometry method was developed for the speciation of inorganic selenium in environmental water samples. A mesoporous zirconia film was simply introduced to coat coal cinder by means of the sol-gel technique, and the adsorptive performance of the coated material for Se(IV)/Se(VI) was investigated in different media. Both Se(IV) and Se(VI) can be retained quantitatively by the material in HCl/NaOH (pH 1.

Tetra-kis(μ-penta-fluoro-benzoato-κO:O')bis-[(tetra-hydro-furan-κO)molybdenum(II)].

In the asymmetric unit of the title compound, [Mo(2)(C(7)F(5)O(2))(4)(C(4)H(8)O)(2)], two independent half-mol-ecules are present, which are completed by a crystallographically imposed center of inversion between the individual Mo atoms. In each mol-ecule, four penta-fluoro-benzoate anions bridge the quadruply bonded Mo(2) (4+) unit that is, in addition, axially coordinated by two O atoms of tetra-hydro-furan (THF) mol-ecules. In the two independent mol-ecules, the mean Mo-Mo bond length is 2.

catena-Poly[[tetra-kis-(μ-penta-fluoro-benzoato-κO:O')dimolybdenum(II)]-μ-4,4'-bipyridine-κN:N'].

In the title compound, [Mo(2)(C(7)F(5)O(2))(4)(C(10)H(8)N(2))](n), the mol-ecule forms a paddle-wheel-type structure. Each Mo(2) (4+) unit is equatorially coordinated by four pentafluoro-benzoate groups, while the axial positions are occupied by two 4,4'-bipyridine mol-ecules. The Mo-Mo bond length of 2.

Supramolecular assemblies of dimolybdenum transoids built by Mo2-enhanced perfluorophenyl-perfluorophenyl synthons.

Two supramolecular assemblies were developed by the dimmolybdenum paddlewheel complex trans-Mo(2)(DAniF)(2)(O(2)CC(6)F(5))(2) (1) (ancillary ligand DAniF = N,N'-di-(p-anisyl)formamidinate) through intermolecular offset face to face C(6)F(5)···C(6)F(5) interactions. The two networks are different because of the presence and absence of tetrahydrofuran (THF) axial coordination to the Mo(2) units, but feature commonly short interplanar distances between the two paired perfluorophenyl groups, that is, 3.30 Å and 3.