Aim: To investigate the involvement of pericyte-Müller glia interaction in retinal damage repair and assess the influence of suppressing the platelet-derived growth factor receptor β (PDGFRβ) signaling pathway in retinal pericytes on photoreceptor loss and Müller glial response.
Methods: Sprague-Dawley rats were exposed to intense light to induce retinal injury. Neutralizing antibody against PDGFRβ were deployed to block the signaling pathway in retinal pericytes through intravitreal injection.
Zhonghua Yan Ke Za Zhi
September 2013
Objective: To study the influence of haliotidis extractive on the oxidative damage in the human lens epithelial cells cultured in vitro.
Methods: Experimental study. Cultured human lens epithelial cells in vitro were intervened with hydrogen peroxide caused oxidative damage model, at the same time added different concentrations of concha haliotidis extractive.