Publications by authors named "Li-Hsin Pan"
Article Synopsis
- Molecular testing is increasingly used for cancer diagnosis, but the accuracy and reliability of these tests are crucial for identifying specific mutations, like BRAF V600E, linked to cancers.
- A 45-year-old woman was found to have a thyroid nodule, and genetic testing showed the BRAF V600E mutation, which suggested papillary thyroid cancer; however, surgery revealed a different diagnosis, minimally invasive follicular carcinoma.
- The case highlights the importance of careful interpretation of molecular test results and suggests using multiple validation methods to confirm genetic findings before making clinical decisions.
Background: Cribriform morular thyroid carcinoma has been recently renamed in the 2022 WHO classification as a thyroid tumor of uncertain histogenesis. The epidemiologic, pathological, and pathophysiological characteristics distinguish it from papillary thyroid carcinoma (PTC). Preoperative genetic testing plays a role in facilitating the differential diagnosis.
View Article and Find Full Text PDFPrimary aldosteronism (PA) is the most common form of endocrine hypertension, characterized by excess aldosterone production that leads to an increased risk of cardiovascular events and target organ damage. Both adrenalectomy and medical treatment have shown efficacy in improving clinical outcomes and comorbidities associated with PA, including a specific subtype of PA with autonomous cortisol secretion (ACS). Understanding the comorbidities of PA and establishing appropriate follow-up protocols after treatment are crucial for physicians to enhance morbidity and mortality outcomes in patients with PA.
View Article and Find Full Text PDFPrognostic predictors of adrenocortical carcinoma: A single-center thirty-year experience.
Front Endocrinol (Lausanne)
March 2023
Background: The prognosis of adrenocortical carcinoma (ACC) is poor but highly variable. The present study aimed to characterize patients with ACC at a single center in Taiwan and to determine the prognostic predictors of overall and progression-free survival.
Methods: Medical records of patients, who were diagnosed with ACC at Taipei Veterans General Hospital between January 1992 and June 2021, were reviewed.