Publications by authors named "Li-Guo Tong"
Article Synopsis
- Cardiomyocyte loss and fibrosis significantly contribute to the damage caused by myocardial infarction (MI), which leads to heart dysfunction.
- Mesenchymal stem cell (MSC)-derived exosomes, especially when combined with Danshen decoction (DSY), show potential in improving heart recovery after MI in rat models.
- The study found that exosomes from BM-MSCs combined with DSY were more effective than standard BM-MSC exosomes in enhancing cardiac function and structure, while also reducing damage and cell death in heart cells.
[A new cucurbitane glycoside from Picrorhiza scrophulariiflora].
Zhongguo Zhong Yao Za Zhi
April 2024
Chemical constituents from the ethanol extract of Picrorhiza scrophulariiflora were isolated and purified by column chromatography. Their structures were identified by HR-MS, 1D and 2D-NMR, and their cytotoxicity was assessed by CCK-8 assay. Four compounds were isolated and identified as follows: 2β-D-glucosyloxy-3β,16α,20β-trihydroxy-9-methyl-19-norlanosterol-5,25-diene-22-one(1), 2β-D-glucosyloxy-3β,16α,20β-trihydroxy-9-methyl-19-norlanosta-5,24-diene-22-one(2), 25-acetoxy-2β-glucosyloxy-3β,16α,20β-trihydroxy-9-methyl-19-norlanosta-5-ene-22-one(3) and 25-acetoxy-2β-glucosyloxy-3β,16α,20β-trihydroxy-9-methyl-19-norlanosta-5,23-(E)-diene-22-one(4).
View Article and Find Full Text PDFTo characterize the chemical constituents of Huanbei Zhike Prescription by ultra-high performance liquid chromatography-time of flight mass spectrometry( UPLC-Q-TOF-MS/MS). A Thermo Syncronls C18 column( 2. 1 mm×100 mm,1.
View Article and Find Full Text PDF[Protective effect of baicalin against rotenone induced injury on PC12 cells].
Zhongguo Zhong Yao Za Zhi
August 2014
Objective: To explore the protective effect of baicalin against rotenone-induced injury on PC12 cells, and the po-tential mechanism of action action was also explored.
Method: PC12 cells were injured by rotenone and were treated with different concentrations (0.1, 1, 10 μmol x L(-1)) of baicalin at the same time.