Publications by authors named "Li-Ge Xiao"
Objectives To find out the prevalence rate of pre-myopia among primary school students in the Mianyang Science City Area, analyze its related risk factors, and thus provide a reference for local authorities to formulate policies on the prevention and control of myopia for primary school students. Methods From September to October 2021, Cluster sampling was adopted by our research group to obtain the vision levels of primary school students employing a diopter test in the Science City Area. In addition, questionnaires were distributed to help us find the risk factors associated with pre-myopia.
View Article and Find Full Text PDFObjectives: To (i) introduce the deformed complex vertebral osteotomy (DCVO) technique for the treatment of severe congenital angular spinal kyphosis; (ii) evaluate the sagittal correction efficacy of the DCVO technique; and (iii) discuss the advantages and limitations of the DCVO technique.
Methods: Multiple malformed vertebrae were considered a malformed complex, and large-range and angle wedge osteotomy was performed within the complex using the DCVO technique. Patients with local kyphosis greater than 80° who were treated with DCVO and did not have tumors, infections, or a history of surgery were included.
Adolescent idiopathic scoliosis (AIS) is a severe spinal deformity that often occurs during puberty. The occurrence of AIS is suggested to be related to abnormal development of cartilage. Our previous study found increased serum ghrelin levels in AIS patients that may linked to the development of AIS.
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- The study investigates the relationship between adiponectin levels and bone mass in adolescents with idiopathic scoliosis (AIS), finding that AIS patients have lower body mass index (BMI) and higher circulating adiponectin compared to controls.
- Elevated levels of adiponectin and a specific genetic variant (rs7639352) were significantly linked to osteopenia in AIS patients, suggesting potential genetic and metabolic factors at play.
- Analysis of bone microstructure revealed that the convex side of the spine in AIS had reduced bone volume and demonstrated different expression levels of bone-related proteins and inflammatory factors compared to the concave side.
Estrogen receptor plays critical roles in osteogenesis but the underlying mechanism remains unclear. In order to determine the effect of ERα and ERβ on several critical factors in regulating osteogenesis in human osteoblasts. Cell based assy, RT-PCR and immunoblot analyses were used in the research.
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