Decomposition-Reassembly Synthesis of a Silverton-Type Polyoxometalate 3D Framework: Semiconducting Properties and Photocatalytic Applications.

Polyoxometalate-based all-inorganic three-dimensional (3D) frameworks have recently attracted attention as a unique class of materials due to their unique physicochemical properties and a wide field of application with excellent prospects. We herein synthesized a novel all-inorganic 3D framework material based on cobalt-substituted Silverton-type polyoxometalate, H{CoWO[Co(HO)]}·2HO (CoW), which was successfully constructed using Na[WCo(HO)(CoWO)]·46-48HO (CoW) and Co(NO)·6HO as starting materials in a hydrothermal reaction via a decomposition-reassembly route together with the rational adjustment of pH values. CoW has been structurally characterized using single-crystal X-ray diffraction.

The association of demodex infestation with pediatric chalazia.

Purpose: This study aimed to investigate the association of Demodex infestation with pediatric chalazia.

Methods: In a prospective study, 446 children with chalazia and 50 children with non-inflammatory eye disease (controls) who underwent surgical treatment were enrolled from December 2018 to December 2019. Patient ages ranged from 7 months to 13 years old.

pH-Controlled assembly of [ZnWO]-based hybrids from a 0D dimer to a 2D network: synthesis, crystal structure, and photocatalytic performance in transformation of toluene into benzaldehyde.

Polyoxometalate-based organic-inorganic hybrids have attracted considerable attention due to their fascinating structures and wide application prospects. In this work, using the same building blocks, ligands and metal ions (ZnWO(ZnW), 2,2'-bipyridine (2,2'-bipy), and Cu), we synthesized three new POM-based hybrids by controlling the pH values of the reaction systems. These three compounds {(Zn(H)WO)[Cu(2,2'-bipy)(HO)][Cu(2,2'-bipy)(HO)][Cu(2,2'-bipy)(HO)]}·6HO (1), (MeN){ZnWO[Cu(2,2'-bipy)(HO)][Cu(2,2'-bipy)(HO)]}·5HO (2), and {(Zn(H)WO)[Cu(2,2'-bipy)][Cu(2,2'-bipy)(HO)][Cu(2,2'-bipy)(HO)]}·5HO (3) have been structurally characterized by single-crystal X-ray diffraction.

An unprecedented polyoxometalate-based 1D double chain compound with opposite charges enables conductivity improvement.

A POM-based one-dimensional (1D) chain compound, {BWO[Cu(2,2'-bipy)][Cu(2,2'-bipy)(HO)]}{BWO[Cu(2,2'-bipy)][Cu(2,2'-bipy)(HO)]}·7HO, has been synthesized and structurally characterized, which represents an unprecedented 1D double chain structure with opposite charges. In contrast to common POMs, this compound exhibits a relatively high electrical conductivity of 1.17 × 10 S cm at 25 °C.

Exploring the Coordination Modes of a Keggin-Type [ZnWO] Anionic Cluster: Bonding Patterns, Crystal Structure, and Semiconducting Properties.

Polyoxometalate-based organic-inorganic hybrid compounds (POIHCs) have been greatly developed due to their wide application prospects, but the pursuit of their directed synthesis via molecular design still remains a challenge. Herein, we demonstrate that the coordination modes of the Keggin-type [ZnWO] anion can be tuned, which leads to different semiconductor characteristics. Using the same building block, ligand, and metal ion (ZnW, phen, Cu), we synthesized three new POIHCs with different bonding patterns by means of different coordination modes of ZnW.

A Deep Learning Based Framework for Diagnosing Multiple Skin Diseases in a Clinical Environment.

Numerous studies have attempted to apply artificial intelligence (AI) in the dermatological field, mainly on the classification and segmentation of various dermatoses. However, researches under real clinical settings are scarce. This study was aimed to construct a novel framework based on deep learning trained by a dataset that represented the real clinical environment in a tertiary class hospital in China, for better adaptation of the AI application in clinical practice among Asian patients.

The Feature Ambiguity Mitigate Operator model helps improve bone fracture detection on X-ray radiograph.

This study was performed to propose a method, the Feature Ambiguity Mitigate Operator (FAMO) model, to mitigate feature ambiguity in bone fracture detection on radiographs of various body parts. A total of 9040 radiographic studies were extracted. These images were classified into several body part types including 1651 hand, 1302 wrist, 406 elbow, 696 shoulder, 1580 pelvic, 948 knee, 1180 ankle, and 1277 foot images.

Activating transcription factor 3 coordinates differentiation of cardiac and hematopoietic progenitors by regulating glucose metabolism.

The cardiac and hematopoietic progenitors (CPs and HPs, respectively) in the mesoderm ultimately form a well-organized circulation system, but mechanisms that reconcile their development remain elusive. We found that activating transcription factor 3 () was highly expressed in the CPs, HPs, and mesoderm, in zebrafish. The mutants exhibited atrial dilated cardiomyopathy and a high ratio of immature myeloid cells.

Real-world impact of postmastectomy radiotherapy in T1-2 breast cancer with one to three positive lymph nodes.

Background: The utility of postmastectomy radiotherapy (PMRT) in breast cancer patients with T1-2 (tumor size ≤5 cm) and N1 (one to three lymph nodes involved) disease remains controversial. The aim of this population-based study was to investigate the effectiveness of PMRT in this patient subset in the current clinical practice.

Methods: We included T1-2N1 breast cancer patients treated with mastectomy from 2004 to 2012 using the data form the Surveillance, Epidemiology, and End Results program.

From a blue to white to yellow emitter: a hexanuclear copper iodide nanocluster.

Highly emissive copper(i) halide nanoclusters showing thermally activated delayed fluorescence (TADF) have been paid much attention, but rarely reported so far. Herein, a hexanuclear copper(i) iodide cluster containing a tridentate N∧P∧N ligand, [CuI(ppda)] {ppda = 2-[2-(dimethylamino)phenyl(phenyl)phosphino]-N,N-dimethylaniline}, was synthesized. All six copper atoms are four-coordinate, including four CuPNI and two CuI units.

Histological Tumor Type is Associated with One-Year Cause-Specific Survival in Women with Stage III-IV Epithelial Ovarian Cancer: A Surveillance, Epidemiology, and End Results (SEER) Database Population Study, 2004-2014.

BACKGROUND The prognosis of epithelial ovarian cancer (EOC) remains poor. Cause-specific survival (CSS) is an overall survival measure of cancer survival that excludes other causes of death. This retrospective population study used the Surveillance, Epidemiology, and End Results (SEER) database to evaluate prognostic factors associated with one-year CSS in women with stage III-IV EOC between 2004-2014.

Omission of adjuvant radiotherapy following breast-conserving surgery for elderly women with early-stage pure mucinous breast carcinoma.

Background: We aimed to ascertain population-based practice patterns and survival outcomes of postoperative radiotherapy following breast conserving-surgery (BCS) in elderly women (aged ≥65 years) with early-stage pure mucinous breast carcinoma (PMBC).

Methods: Patients aged ≥65 years diagnosed with T1-2N0 and hormone receptor-positive PMBC between 1990 and 2010 were identified from the Surveillance, Epidemiology, and End Results database. Binomial logistic regression, Kaplan-Meier method, Multivariate Cox proportional hazards models, and propensity score matching (PSM) were used for statistical analysis.

21-Gene Recurrence Score Assay Could Not Predict Benefit of Post-mastectomy Radiotherapy in T1-2 N1mic ER-Positive HER2-Negative Breast Cancer.

It is still controversial whether post-mastectomy radiotherapy (PMRT) is necessary for women with T1-2 N1mic ER-positive HER2-negative breast cancer. The 21-gene recurrence score (RS) assay has been validated in T1-2 N1 breast cancer to be prognostic of locoregional recurrence (LRR) and overall survival (OS). This study aims to evaluate the predict value of 21-gene recurrence score assay for the benefit of PMRT in T1-2 N1mic ER-positive HER2-negative breast cancer.

21-gene recurrence score and adjuvant chemotherapy decisions in patients with invasive lobular breast cancer.

Aim: To determine the effect of the 21-gene recurrence score (RS) on outcome and chemotherapy decision in breast invasive lobular carcinoma (ILC).

Materials & Methods: We included 6467 patients with early stage and estrogen receptor-positive ILC from the Surveillance, epidemiology, and end results database.

Results: A total of 9.

Clinicopathologic characteristics and clinical outcomes of pure type and mixed type of tubular carcinoma of the breast: a single-institution cohort study.

Introduction: We aimed to evaluate the clinicopathologic characteristics and clinical outcomes of the mixed type versus the pure type of tubular carcinoma (TC) of the breast in a retrospective cohort study.

Materials And Methods: Patients were categorized into the following three groups: patients with pure TC of the breast (the PTC group), patients with TC and carcinoma in situ of the breast (the TC-CIS group), and patients with TC and other invasive carcinomas of the breast (the TC-IC group). We compared the clinicopathologic characteristics and treatment outcomes of the three groups.

Patterns of Distant Metastasis Between Histological Types in Esophageal Cancer.

Distant metastasis remains the major cause of treatment failure in esophageal cancer, though there have been few large-scale studies of the patterns of distant metastasis in different histological types. We investigated the patterns of distant metastasis in esophageal adenocarcinoma (AC) and squamous cell carcinoma (SCC) using a population-based approach. Patients with stage IV esophageal cancer at diagnosis were identified using the Surveillance, Epidemiology, and End Results database.

Long-term survival effect of the interval between mastectomy and radiotherapy in locally advanced breast cancer.

Introduction: The timing of postmastectomy radiotherapy (PMRT) may influence locoregional recurrence and survival outcomes. In this study, we assessed the long-term survival effect of the interval between surgery and PMRT in locally advanced breast cancer treated with mastectomy and adjuvant chemotherapy.

Methods: In this retrospective study, we included women with locally advanced breast cancer who underwent adjuvant chemotherapy and PMRT after mastectomy between 1999 and 2007.

Tubular carcinomas of the breast: an epidemiologic study.

Aim: We explored the clinicopathologic characteristics, prognostic factors and outcomes in tubular carcinoma (TC) of the breast.

Methods: We retrospectively assessed 8091 TC patients using the SEER database from 2000 to 2013.

Results: Most patients were non-Hispanic white, well-differentiated disease, tumor size ≤2 cm, node-negative, nonmetastatic, hormone receptor-positive and HER2-negative status.

Omission of Postoperative Radiotherapy in Women Aged 65 Years or Older With Tubular Carcinoma of the Breast After Breast-Conserving Surgery.

Introduction: To investigate the temporal trends of postoperative radiotherapy (RT) administration and the effects of omitting postoperative RT on breast cancer-specific survival (BCSS) in women aged ≥65 years with tubular carcinoma (TC) of the breast who received breast-conserving surgery (BCS).

Methods: We included women aged 65 years with non-metastatic TC of the breast who underwent BCS between 2000 and 2013 using the Surveillance, Epidemiology, and End Results database. Statistical analyses were performed using chi-square tests, Kaplan-Meier analyses, Cox proportional hazards models, and a 1:1 propensity score matching (PSM).

Lymph node ratio has prognostic value related to the number of positive lymph nodes in patients with vulvar cancer.

Aim: We investigated the value of the number of positive lymph nodes (PLNs) and lymph node ratio (LNR) on survival of vulvar cancer patients.

Methods: A total of 2332 patients with vulvar squamous cell carcinoma were included from the SEER program.

Results: In multivariate analysis, the number of PLNs and LNR were independent prognostic indictors of survival outcomes, a higher number of PLNs and a higher LNR had poorer survival outcomes.

Widowed status increases the risk of death in vulvar cancer.

Aim: To evaluate the effect of marital status on survival of patients with vulvar cancer.

Materials & Methods: A total of 4001 patients with vulvar cancer were included from the SEER database. Statistical analyses were performed using χ test, Kaplan-Meier method, Cox regression proportional hazards and a 1:1 propensity score-matching.

The Clinicopathological Features and Survival Outcomes of Different Histological Subtypes in Triple-negative Breast Cancer.

To determine the clinicopathological features and survival outcomes of triple-negative breast cancer (TNBC) according to different histological subtypes. Using the Surveillance, Epidemiology, and End Results database, we included TNBC cases in 2010-2013. The effect of histological subtype on breast cancer-specific survival (BCSS) and overall survival (OS) were analyzed using univariate and multivariate analyses.