accelerates stem cell recruitment to human skeletal muscle after exercise.

is a parasitic fungus known to induce immune responses. The impact of supplementation on stem cell homing and expansion to human skeletal muscle after exercise remains unexplored. In this study, we examined how pre-exercise supplementation influences cell infiltration, CD34 cell recruitment, and Pax7 cell expansion in human skeletal muscle after high-intensity interval exercise (HIIE) on a cycloergometer.

Senolytic effect of high intensity interval exercise on human skeletal muscle.

p16 expression is a robust biomarker of senescence for stem cells in human tissues. Here we examined the effect of exercise intensity on senescence in skeletal muscle, using a randomized counter-balanced crossover design. Biopsied vastus lateralis of 9 sedentary men (age 26.

Effects of Hypoxia-Hyperoxia Preconditioning on Indicators of Muscle Damage After Acute Resistance Exercise in Male Athletes.

Purpose: The purpose of this study was to investigate the effects of acute repeated hypoxia-hyperoxia preconditioning on resistance exercise (RE)-induced muscle damage in male athletes.

Methods: Eleven young male athletes participated in this randomized double-blind counter-balanced crossover study, and were divided into Normoxia (N) and Hypoxia-Hyperoxia (HH) trials. Subjects of the respective trials were supplied with normoxic (FiO = 0.

Vascular function in the aging human brain during muscle exertion.

To determine how brain oxygenation is stably maintained during advancing age, cerebral oxygenation and hemoglobin were measured real-time at 10 Hz using near-infrared spectroscopy (NIRS) at rest (30 seconds) and during a 10-repeated handgrip strength test (30 seconds) for 834 adults (M/F = 45/55%) aged 20-88 y. The amplitude of cerebral hemodynamic fluctuation was reflected by converting 300 values of % oxygen saturation and hemoglobin of each 30-second phase to standard deviation as indicatives of brain oxygenation variability (BOV) and brain hemodynamic variability (BHV) for each participant. Both BOV (+21-72%) and BHV (+94-158%) increased during the maximal voluntary muscle exertions for all age levels (α < 0.