Publications by authors named "Li-Er Mo"
Inhibitory effect of aloe-emodin on metastasis potential in HO-8910PM cell line.
J Asian Nat Prod Res
September 2008
Aloe-emodin (AE) has been demonstrated to have antitumor activity in several tumor cells. However, no information is available on the effect of AE on metastasis in human carcinoma cells. This study was designed to investigate the inhibitory effect of AE on the metastasis potential of HO-8910PM cell line in vitro, and the role of AE in focal adhesion kinase (FAK) expression.
View Article and Find Full Text PDFObjective: To investigate the inhibitory effect of resveratrol on the metastasis-associated ability of human highly metastatic ovarian carcinoma HO-8910PM cells in vitro.
Methods: MTf assay was used to examine the cytotoxicity of resveratrol in HO-8910PM cells; Transwell Chamber assay was performed to determine the effect on invasion and migratory capacity of the cells by resveratrol; Effect on adhesion potential of HO-8910PM cells was tested by cell-Matrigel adhesion assay.
Results: Resveratrol showed no cytotoxicity on HO-8910PM cells after 6 h treatment.
Background & Objective: Cantharidin, a natural toxin, has specific antitumor actions. Many researches confirmed that nuclear factor-kappaB (NF-kappaB) closely relates with invasion and metastasis of tumor. This study was designed to investigate inhibitory effect of cantharidin on metastasis-related ability of human highly metastatic ovarian carcinoma cell line HO-8910PM, and its mechanism.
View Article and Find Full Text PDFAim: To study the direct effect and kinetics of sodium quercetin-7,4'-disulphate (SQDS) on recombinant human protein kinase CK2 holoenzyme.
Methods: The recombinant human CK2 holoenzyme activity was assayed by detecting incorporation of 32P of [gamma-32P] ATP into the substrate in various conditions.
Results: The recombinant human CK2 was a second messenger (Ca2+, cAMP and cGMP) independent protein kinase.