Urothelial carcinoma (UC) is characterized by a high incidence of mutation, and overcoming resistance to cisplatin-based chemotherapy in UC is a major concern. Wee1 is a G2/M phase regulator that controls the DNA damage response to chemotherapy in -mutant cancers. The combination of Wee1 blockade with cisplatin has shown synergistic efficacy in several types of cancers, but little is known regarding UC.
View Article and Find Full Text PDFInt J Environ Res Public Health
January 2018
Low-carbon logistics meets the requirements of a low-carbon economy and is the most effective operating model for logistic development to achieve sustainability by coping with severe energy consumption and global warming. Low-carbon logistics aims to reduce carbon intensity rather than simply reduce energy consumption and carbon emissions. Human resources are an important part of the great competition in the logistics market and significantly affect the operations of enterprises.
View Article and Find Full Text PDFFinancial supervision means that monetary authorities have the power to supervise and manage financial institutions according to laws. Monetary authorities have this power because of the requirements of improving financial services, protecting the rights of depositors, adapting to industrial development, ensuring financial fair trade, and maintaining stable financial order. To establish evaluation criteria for bank supervision in China, this study integrated fuzzy theory and the decision making trial and evaluation laboratory (DEMATEL) and proposes a fuzzy-DEMATEL model.
View Article and Find Full Text PDFR&D professionals are the impetus behind technological innovation, and their competitiveness and capability drive the growth of a company. However, high-tech industries have a chronic shortage of such indispensable professionals. Accordingly, reducing R&D personnel turnover has become a major human resource management challenge facing innovative companies.
View Article and Find Full Text PDFIEEE Trans Image Process
July 2015
In this paper, a halftoning-based multilayer watermarking of low computational complexity is proposed. An additional data-hiding technique is also employed to embed multiple watermarks into the watermark to be embedded to improve the security and embedding capacity. At the encoder, the efficient direct binary search method is employed to generate 256 reference tables to ensure the output is in halftone format.
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