Publications by authors named "Li-Chen Ni"
Org Biomol Chem
September 2012
Article Synopsis
- Researchers developed a method for creating optically active tetrahydroquinolines using a gold(I)/Brønsted acid system that combines aminobenzaldehydes or aminophenones with alkynes in one-step reactions.
- This new approach allows for efficient synthesis of compounds with varying chiral centers and functional groups, achieving good to excellent yields while maintaining high selectivity in terms of regio-, diastereo-, and enantioselectivity.
- Initial studies indicate that the stereochemistry of these compounds may influence their biological activity, highlighting their potential for use in drug discovery.
