Publications by authors named "Li-Chaoyue Sun"
Hum Genomics
December 2024
Article Synopsis
- Recent studies have focused on the link between genetic variations (polymorphisms) and aspirin resistance (AR) in patients with ischemic diseases, aiming to identify potential biomarkers for genetic testing before prescribing aspirin.
- The research involved analyzing 75 articles and evaluating 94 candidate gene polymorphisms, with 25 genes undergoing meta-analysis, revealing 23 significant associations with AR, including notable genes like PTGS2 and ITGA2.
- Subgroup analyses further highlighted specific genetic variations associated with AR across different populations, emphasizing the need for tailored approaches in aspirin therapy based on genetic profiles.
