Publications by authors named "Li-Cai Mo"
Front Oncol
November 2022
Article Synopsis
- The study focuses on improving predictions of clinically significant prostate cancer (csPCa) using multiparametric MRI (mpMRI) and the Prostate Health Index (PHI) in a group of 315 men scheduled for prostate biopsies.
- A nomogram was developed based on a multivariate model that combined PHI, mpMRI assessments (using PI-RADS V2), free PSA (fPSA), and prostate volume to enhance prediction accuracy.
- The results indicated that the proposed model significantly outperforms traditional methods, reducing unnecessary biopsies while effectively identifying csPCa.*
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Hum Vaccin Immunother
December 2022
Article Synopsis
- - The study investigated how health behaviors correlated with COVID-19 vaccination among healthcare workers in Taizhou, China, using an online survey conducted in May 2021.
- - Out of 660 staff members, 592 responded, with findings indicating no major differences in health behaviors pre and post-vaccination, except for glove usage, which was higher among vaccinated individuals.
- - Interestingly, those vaccinated earlier reported improved health behaviors, showing increased mask-wearing, handwashing, and glove use after vaccination, suggesting that risk compensation did not occur in this group.
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Article Synopsis
- The study investigates the expression of inhibin βE (INHBE) in clear-cell renal cell carcinoma (ccRCC) patients to determine its role in cancer progression.
- Researchers analyzed RNA sequencing data and conducted immunohistochemistry on tumor samples, finding increased levels of INHBE mRNA and protein in cancer tissues compared to normal samples.
- The findings suggest that higher inhibin βE levels are associated with worse tumor grades and shorter survival rates, indicating its potential role as a tumor promoter in ccRCC.
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World J Clin Cases
June 2021
Article Synopsis
- Pelvic lipomatosis (PL) is a rare condition characterized by abnormal fat growth that compresses pelvic organs, often causing lower urinary tract symptoms (LUTS) and is associated with cystitis glandularis (CG).
- A patient with PL and CG was treated with a procedure called transurethral resection of bladder tumor (TUR-BT) and oral celecoxib, which relieved LUTS and improved bladder examination results.
- This case suggests that celecoxib, a COX-2 inhibitor, might be an effective treatment option for PL in combination with refractory CG, highlighting the potential role of COX-2 in this condition.
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