[A process-based model and simulation system of dynamic change and spatial variation in large-scale terrestrial ecosystems].

More attention has been paid to the monitoring, assessment, prediction, early warning and sustainable management of regional ecological environment and the changes of ecosystem state in recent years. It is an important scientific and technological task to develop quantitative methods and numerical simulation techniques for ecosystem modelling, and to construct the continental scale numerical simulator with the characteristics of multi-process coupling, multi-technology integration, and multi-objective application for stimulating research on ecosystem and global change and its resources, environment and disaster effects, based on the in-depth understanding of the components, processes, functions, patterns, and their interaction mechanism of terrestrial ecosystem. Here, we reviewed the current status and future direction of terrestrial ecosystem models, and discussed the conceptual framework of developing the simulation system of dynamic change and spatial variation in large-scale terrestrial ecosystems and its resource and environment effect, as well as basic issues on the function orientation and structure design of the simulation system, which would provide reference for constructing Chinese terrestrial ecosystem numerical simulator.

[Effects of decitabine on biological behavior of U266 cells].

This study was aimed to explore the effects of decitabine on the biological behaviour of U266 cells in vitro so as to provide a new thinking and experiment basis, as well as new evidences for the pathogenesis of multiple myeloma. MTT and colony formation assays were used to evaluate the impact of decitabine on the ability of proliferation of U266 cells; flow cytometry was used to analyze the cell distribution in cell cycle; transwell chamber and matrigel assays were used to observe the ability of migration and invasion. The results indicated that decitabine could significantly suppress the proliferation of U266 cells in time-and dose-dependent manners.