Publications by authors named "Li Ying Wong"
J Community Genet
November 2024
Article Synopsis
- The study investigates the prevalence of the HLA-B*58:01 allele, which is linked to severe skin reactions from allopurinol, among gout patients in Malaysia's multiethnic population.
- A total of 547 patients from Malay, Chinese, and Indian backgrounds were tested, revealing an overall allele prevalence of 16.8%, with the highest at 21.8% in Chinese patients.
- Notably, despite having the HLA-B*58:01 allele, none of the patients who used allopurinol developed severe cutaneous reactions, indicating the need for a better predictive model for these reactions.
