Non-enveloped virus inactivation potency of sodium dodecyl sulfate with citric and glutamic acids.

Disinfection is one of the most important methods by which transmission of infectious diseases can be blocked, and efficacies differ depending on how they are used and the target organism. Small non-enveloped viruses are considerably less sensitive to disinfectants than enveloped viruses and vegetative bacteria or fungi and generally require strong protein-disrupting chemicals for effective inactivation, limiting their application in personal care products due to associated side effects. Sodium dodecyl sulfate (SDS) is a common anionic surfactant and relatively safe ingredient used in many personal care and hygiene products possessing protein-denaturing properties and has been reported to have antimicrobial efficacy against enveloped viruses and bacteria.