Effect of electrical stimulation in the treatment on patients with foot drop after stroke: a Systematic Review and Network Meta-analysis.

Objective: To systematically evaluate the efficacy of electrical stimulation (ES) in the treatment of patients with foot drop (FD) after stroke, and to compare the efficacy of different types of ES.

Data Sources: We searched 5 English database (PubMed, Web of Science, Embase, Cochrane Library and Scopus) and 4 Chinese databases (China National Knowledge Infrastructure (CNKI), SinoMed (CBM), VIP and Wanfang Data) from inception to June, 2024.

Data Synthesis: Traditional meta-analysis and network meta-analysis were performed using RevMan5.

Distinct assembly processes of intestinal and non-intestinal microbes of bark beetles from clues of metagenomic insights.

Ips (Curculionidae: Scolytinae) bark beetles (BBs) are ecologically and economically devastating coniferous pests in the Northern Hemisphere. Although the microbial diversity associated with these beetles has been well studied, mechanisms of community assembly and the functional roles of key microbes remain poorly understood. This study investigates the microbial community structures and functions in both intestinal and non-intestinal environments of five Ips BBs using a metagenomic approach.

Fast reconstruction and optical-sectioning three-dimensional structured illumination microscopy.

Three-dimensional structured illumination microscopy (3DSIM) is a popular method for observing subcellular/cellular structures or animal/plant tissues with gentle phototoxicity and 3D super-resolution. However, its time-consuming reconstruction process poses challenges for high-throughput imaging and real-time observation. Moreover, traditional 3DSIM typically requires more than six layers for successful reconstruction and is susceptible to defocused backgrounds.

Natural variation in the GmVPE1 promoter contributes to phosphorus re-translocation to seeds and improves soybean yield.

Phosphorus (P) is an essential yet frequently deficient plant nutrient. Optimizing P distribution and recycling between tissues is vital for improving P utilization efficiency (PUE). Yet, the mechanisms underlying the transport and re-translocation of P within plants remain unclear.

The influence of temperature and pressure on the self-diffusion characteristics and mechanical sensitivity of DNTF: a molecular dynamics study.

Context: 3,4-Bis(3-nitrofurazan-4-yl) furoxan (DNTF) is a typical low-melting-point, high-energy-density compound that can serve as a cast carrier explosive. Therefore, understanding the safety of DNTF under different casting processes is of great significance for its efficient application. This study employed molecular dynamics simulations to investigate the effects of temperature and pressure on the self-diffusion characteristics and mechanical sensitivity of DNTF.

Correction: Potentiating light-harvesting tactics through an A-D-A structure: repolarization of tumor-associated macrophages through phototherapy.

Correction for 'Potentiating light-harvesting tactics through an A-D-A structure: repolarization of tumor-associated macrophages through phototherapy' by Pai Liu , , 2024, , 7870-7878, https://doi.org/10.1039/D4TB00814F.

Displacement Measurement Based on the Missing-Order Talbot Effect.

Displacement measurement is a crucial application, with laser-based methods offering high precision and being well established in commercial settings. However, these methods often come with the drawbacks of significant size and exorbitant costs. We introduce a novel displacement measurement method that utilizes the missing-order Talbot effect.

Bio-inspired space-filling fractal metamaterial.

Inspired by mammal cranial sutures with spatiotemporal morphological variation, two-phase space-filling fractal metamaterial was designed. Designs with different levels of complexity are fabricated via multi-material polymer jetting. Mechanical tests and systematic finite element (FE) simulations are conducted to evaluate the mechanical performance of the designs.

Development and validation of the ethnic trust scale in China.

Background: Considerable research has shown that ethnic trust reflects the existence of friendly relations among all ethnic groups and ethnic individuals, and can help in resolving ethnic conflicts and contradictions, promoting exchanges among various ethnic groups, which is highly relevant to social stability.

Methods: This research, including three studies, aimed to explore the conceptual structure of ethnic trust in China, and develop and validate a measurement of the ethnic trust scale. In the first study, we used free association and in-depth interview methodology, applied cluster analysis, multidimensional scaling analysis, and grounded theory to construct the theoretical framework of Chinese people's ethnic trust concept.

Ethnic sensitivity analyses of pharmacokinetics, efficacy and safety in polycythemia vera treatment with ropeginterferon alfa-2b.

Ropeginterferon alfa-2b (Ropeg) is approved for the treatment of adults with polycythemia vera (PV). This report aims to analyze the ethnic sensitivity of Ropeg for the treatment of PV, comparing the pharmacokinetics (PK), efficacy, and safety profiles across diverse ethnic groups. We conducted a relevant review of PV and analysis of data obtained from clinical studies involving Ropeg.

Susceptibility of Lymantria dispar to Beauveria bassiana under short-term Cd stress: Humoral immunostimulation cannot offset cellular immunotoxicity.

Heavy metal is a serious environmental pollutant with all kinds of biotoxic effects. The immunomodulatory effects of Cd stress on Lymantria dispar larvae and its underlying mechanisms were investigated. The susceptibility of Cd-treated larvae to Beauveria bassiana (Bb) was significantly increased by 27.

Strain-tunable electronic anisotropy of the AlSb double-layer honeycomb structure.

Two-dimensional (2D) materials show promising applications in nanoelectronic devices due to their excellent physical and chemical properties, large specific surface area, and good flexibility. 2D AlSb, a representative of a new class of two-dimensional materials with a double-layer honeycomb (DLHC) structure was recently obtained in experiments and was reported to be a direct band gap semiconductor. Strain engineering is an effective way of tuning the properties of 2D materials.

Systemic immune-inflammation and prognostic immune nutritional index in oral squamous cell carcinoma patients.

To investigate the systemic immune-inflammation index and prognostic immune nutritional index in the prognostic evaluation of oral squamous cell carcinoma. We analyzed retrospectively the relationship between systemic immune-inflammation index, prognostic immune nutritional index and clinicopathological variables and the overall survival of 262 patients who underwent radical surgery. Multivariate analysis showed high systemic immune-inflammation index (Hazard ratio = 3.

Sex Differences in Antennal Transcriptome of and Analysis of Odorant Receptor Expression Profiles.

Insects rely on olfaction for mating, finding oviposition sites, and locating hosts. is a serious pest that severely damages forests. Differential expression analysis of olfactory-related genes between males and females is the basis for elucidating the functions of olfactory-related proteins in .

On-demand auxeticity and co-existing pre-tension induced compression stage in a sandwich design with kinematically constrained 3D suture tiles.

By incorporating concepts from auxeticity, kinematic constraints, pre-tension induced compression (PIC), and suture tessellations, tiled sandwich composites are designed, demonstrating behaviors attributed to the synergy between auxeticity and pre-tension induced contact and compression, simultaneously triggered by a threshold strain. The designs can theoretically achieve on-demand Poisson's ratio in the widest range (-∞, +∞), and once triggered, the Poisson's ratio is stable under large deformation. Also, once the overall strain goes beyond the threshold, the designs enter into a PIC stage, ensuring the middle soft layer takes the tensile load, while the tiles are under compression via contact and the 3D articulation of the tooth-channel pairs.

GDNF-induced phosphorylation of MUC21 promotes pancreatic cancer perineural invasion and metastasis by activating RAC2 GTPase.

Perineural invasion (PNI) is an adverse prognostic feature of pancreatic ductal adenocarcinoma (PDAC). However, the understanding of the interactions between tumors and neural signaling within the tumor microenvironment is limited. In the present study, we found that MUC21 servers as an independent risk factor for poor prognosis in PDAC.

Potentiating light-harvesting tactics through an A-D-A structure: repolarization of tumor-associated macrophages through phototherapy.

Aiming to decrease the recurrence of tumors and achieve patient satisfaction, the elicitation of immunotherapy and its integrated synergistic employment is a bright new direction in oncotherapy, yet an emergently challenging task. In particular, tumor-associated macrophage (TAM) regulation though light-induced photodynamic and photothermal therapy (PDT and PTT) is regarded as a powerful approach, which focuses on the systemic immune system instead of the tumor itself. Herein, this study reports an acceptor-donor-acceptor (A-D-A) aggregation-induced emission luminogen (AIEgen), named TPA-2CN, which was applied as a photosensitizer (PS) and photothermal agent (PTA).

Molecular Engineering of Hydrogen-Bonded Organic Framework for Enhanced Nitrate Electroreduction to Ammonia.

Electrocatalytic nitrate reduction is an efficient way to produce ammonia sustainably. Herein, we rationally designed a copper metalloporphyrin-based hydrogen-bonded organic framework (HOF-Cu) through molecular engineering strategies for electrochemical nitrate reduction. As a result, the state-of-the-art HOF-Cu catalyst exhibits high NH Faradaic efficiency of 93.

Direction-dependent bending resistance of 3D printed bio-inspired composites with asymmetric 3D articulated tiles.

Inspired by the protective armors in nature, composites with asymmetric 3D articulated tiles attached to a soft layer are designed and fabricated via a multi-material 3D printer. The bending resistance of the new designs are characterized via three-point bending experiments. Bending rigidity, strength, and final deflection of the designs are quantified and compared when loaded in two different in-plane and two different out-of-plane directions.

Manganese/Enzyme Sequential Catalytic Pathway for the Production of Optically Active γ-Functionalized Alcohols.

A brief, practical catalytic process for the production of optically active γ-functionalized alcohols from relevant alkenes has been developed by using a robust Mn(III)/air/(MeSiH)O catalytic system combined with lipase-catalyzed kinetic resolution. This approach demonstrates exceptional tolerance toward proximal functional groups present on alkenes, enabling the achievement of high yields and exclusive enantioselectivity. Under this sequential catalytic system, the chiral alkene precursors can also be converted into γ-functionalized alcohols and related acetates as separable single enantiomers.

Sonodynamic Therapy-Driven Immunotherapy: Constructing AIE Organic Sonosensitizers Using an Advanced Receptor-Regulated Strategy.

Benefit from the deeper penetration of mechanical wave, ultrasound (US)-based sonodynamic therapy (SDT) executes gratifying efficacy in treating deep-seated tumors. Nevertheless, the complicated mechanism of SDT undeniably hinders the exploration of ingenious sonosensitizers. Herein, a receptor engineering strategy of aggregation-induced emission (AIE) sonosensitizers (TPA-Tpy) with acceptor (A)-donor (D)-A' structure is proposed, which inspects the effect of increased cationizations on US sensitivity.

Physiotherapeutic Scoliosis-Specific Exercise for the Treatment of Adolescent Idiopathic Scoliosis: A Systematic Review and Network Meta-analysis.

Objective: The aim of the study is to compare the rehabilitative efficacy of different physiotherapy scoliosis-specific exercises for adolescent idiopathic scoliosis using a network meta-analysis.

Design: PubMed, Cochrane Library, Web of Science, Embase, VIP Database for Chinese Technical Periodicals, China National Knowledge Infrastructure, Chinese Biomedical Literature Database, and Wan Fang Data were searched until October 2023. Meta-analysis and network meta-analysis were conducted using RevMan 5.