Publications by authors named "Li Xin Xu"

This paper proposes a dual-band patch antenna with combined self-decoupling and filtering properties, designed to suppress mutual coupling between two antenna elements both within the same dual-band and across different dual-bands. Initially, a dual-band aperture-coupled filtering patch antenna is designed, featuring a forked short-circuited SIR feedline with a quarter-wavelength open-ended stub and a U-shaped patch with two U-slots, which generate three controllable radiation nulls while introducing two additional resonant modes. The design steps are also provided in detail.

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  • * A study comparing 54 AA patients to 66 controls found increased CRHR1 expression primarily in circulating monocytes of AA patients, suggesting a strong immunological component linked to stress.
  • * Higher CRHR1 levels were correlated with chronic AA and larger lesion sizes, indicating that stress factors may worsen the condition and highlighting the importance of immune system interactions in AA progression.
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Objective: To evaluate the clinical efficacy of digital subtraction angiography (DSA) performed via femoral artery and radial artery approaches.

Methods: This retrospective study included 480 patients requiring cerebral vascular angiography at the First People's Hospital of Changde City from March 2020 to February 2022. Patients were divided into the femoral artery group (transfemoral approach, n=400) and the radial artery group (transradial approach, n=80) according to the surgical route.

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Aims/hypothesis: The relationship between metabolic dysfunction-associated steatotic liver disease (MASLD) and type 2 diabetes mellitus, insulin resistance and the metabolic syndrome is well established. While zinc finger BED-type containing 3 (ZBED3) has been linked to type 2 diabetes mellitus and the metabolic syndrome, its role in MASLD remains unclear. In this study, we aimed to investigate the function of ZBED3 in the context of MASLD.

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As a plant-specific transcription factor, lateral organ boundaries domain (LBD) protein was reported to regulate plant growth and stress response, but the functional research of subfamily II genes is limited. SlMYC2, a master regulator of Jasmonic acid response, has been found to exhibit high expression levels in fruit and has been implicated in the regulation of fruit ripening and resistance to Botrytis. However, its role in fruit expansion remains unknown.

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. In this study, we propose a model called DEPMSCNet (a multiscale self-calibration network) that has a high sensitivity and low false positive rate for detecting pulmonary nodules..

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The epidemic of avian coccidiosis seriously threatens the animals' welfare and the economic gains of the poultry industry. Widespread in avian coccidiosis, () could obviously impair the production performance of the infected chickens. So far, few effective vaccines targeting have been reported, and the nanovaccines composed of nanospheres captured our particular attention.

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  • Haemonchus contortus proteins Hc-ARF1 and Hc-HCA59 are crucial in regulating immune responses in host cells, but their protective effectiveness remains largely unexplored.
  • Researchers combined recombinant Hc-HCA59 and Hc-ARF1 proteins with PLGA nanoparticles to test their protective potential against H. contortus in goats.
  • Results showed significant increases in immune markers and a notable decrease in worm burdens and fecal eggs in the group receiving the combined proteins, indicating their potential as candidates for developing nano vaccines against goat haemonchosis.
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With a worldwide distribution, Eimeria spp. could result in serious economic losses to the poultry industry. Due to drug resistance and residues, there are no ideal drugs and vaccines against Eimeria spp.

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Caused by , toxoplasmosis has aroused great threats to public health around the world. So far, no effective vaccine or drug is commercially available, and the demands for a safe and effective therapeutic strategy have become more and more urgent. In the current study, we constructed a DNA vaccine encoding ribosomal P2 protein (TgP2) and denoted as TgP2-pVAX1 plasmid.

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  • Trehalose-6-phosphate phosphatase (TPP6) is crucial for the trehalose biosynthesis pathway and its accumulation in the body harms the pathogen Haemonchus contortus, although little is known about TPP6 from this parasite.
  • The study involved cloning the HcGOB gene from H. contortus and expressing the rHcGOB protein, followed by assessing its transcription during various developmental stages and its effects on goat immune cells (PBMCs).
  • Results indicated that HcGOB is most active in eggs and infective larvae, binds to PBMCs, and modulates immune responses by activating certain pathways while suppressing others, highlighting its potential as a vaccine
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Purpose: Little is known about how biomechanics governs the biological nature for humeral motion dynamically. Elbow motion ought to be investigated based on a musculoskeletal model and evidence the physiologic principle of upper limbs.

Method: A humeral model was reconstructed by MIMICS after CT images input in *.

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Introduction: Anterior serratus muscle plane block is a novel regional block technique for blockade of the sensory plane of the lateral cutaneous branch of the intercostal nerve (T2-T9), which effectively relieves the pain of patients and improves the quality of recovery. This study aimed to observe the early effectiveness and safety of serratus anterior plane block combined with general anesthesia and patient-controlled serratus anterior plane block in early postoperative recovery in breast cancer.

Methods: The study involved a total of 84 patients undergoing radical mastectomy in our hospital.

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Silent information regulator 2 (SIR2) in histone deacetylase (HDAC) is particularly conserved and widely expressed in all eukaryotic cells. HDAC is a crucial post-translational modification protein regulating gene expression. In the present study, a Toxoplasma gondii (T.

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Previously, it was found that several proteins of Haemonchus contortus were involved in the stimulation of the host immune system. However, the information about the selection of superlative antigens with immunogenic efficacies on host DCs is lacking. In the current study, the stimulatory effects of five recombinant proteins (elongation factor-1α, arginine kinase, ES-15, ES-24, and ADP-ribosylation factor 1) of H.

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  • HCA59, an important protein from the parasite Haemonchus contortus, shows potential to modulate the immune response in goats but its protective capabilities are not well understood.
  • Researchers tested a vaccine using recombinant HCA59 combined with PLGA nanoparticles on goats to evaluate its effectiveness against H. contortus infection.
  • The results revealed that vaccinated goats had a significant increase in antibody and cytokine levels, and a notable reduction in fecal egg counts and worm burdens, indicating that the vaccine could offer partial protection against the parasite.
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Suppression and modulation of the host immune response to parasitic nematodes have been extensively studied. In the present study, we cloned and produced recombinant electron transfer flavoprotein α subunit (ETFα) protein from Haemonchus contortus (rHCETFα), a parasitic nematode of small ruminants, and studied the effect of this protein on modulating the immune response of goat peripheral blood mononuclear cells (PBMCs) and monocytes. Immunohistochemical tests verified that the HCETFα protein was localized mainly in the intestinal wall and on the body surface of worms.

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Background And Objectives: To compare mechanical properties of femoral tumor treatments so that better operative strategy for limb tumors surgery is optimized.

Methods: Fourteen femoral CT images were randomly selected to rebuild 3D models by MIMICS. They were then executed by reverse engineering softwares for simulative modes.

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Background: Modulation of the host immune response by nematode parasites has been widely reported. Rhodaneses (thiosulfate: cyanide sulfurtransferases) are present in a wide range of organisms, such as archaea, bacteria, fungi, plants and animals. Previously, it was reported that a rhodanese homologue could be bound by goat peripheral blood mononuclear cells (PBMCs) in vivo.

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Background: The World Health Organization End TB Strategy meant that compared with 2015 baseline, the reduction in pulmonary tuberculosis (PTB) incidence should be 20 and 50% in 2020 and 2025, respectively. The case number of PTB in China accounted for 9% of the global total in 2018, which ranked the second high in the world. From 2007 to 2019, 854 672 active PTB cases were registered and treated in Henan Province, China.

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Suppression and modulation of the host immune response to parasitic nematodes have been extensively studied. In the present study, we cloned and produced recombinant phosphotyrosyl phosphatase activator protein from Haemonchus contortus (rHCPTPA), a parasitic nematode of small ruminants, and studied the effect of this protein on modulating the immune response of goat peripheral blood mononuclear cells. Enzymatic assays revealed that rHCPTPA enhanced the p-nitrophenylphosphate phosphatase activity of bovine PP2A.

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  • The study focuses on how standardized cancer pain management affects lung cancer patients with bone metastasis in China.
  • It compares two groups: one receiving conventional pain management and the other receiving standardized pain management, analyzing demographics, pain relief, and satisfaction levels.
  • Results show that patients in the standardized group experienced greater pain relief and higher satisfaction, highlighting the benefits of consistent pain management strategies.
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Brain edema is a common and serious complication of ischemic stroke with limited effective treatment. We previously reported that methylene blue (MB) attenuated ischemic brain edema in rats, but the underlying mechanisms remained unknown. Aquaporin 4 (AQP4) in astrocytes plays a key role in brain edema.

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Glioblastoma is a common, malignant brain tumor whose disease incidence increases with age. Glioblastoma stem-like cells (GSCs) are thought to contribute to cancer therapy resistance and to be responsible for tumor initiation, maintenance, and recurrence. This study utilizes both SNP array and gene expression profiling to better understand GSCs and their relation to malignant disease.

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  • The study compares the mechanical behaviors of five common fixation methods for Pauwels-III fractures, including Locking Plate (LP), Dynamic Hip Screw (DHS), Multiple Lag Screw (MLS), and a mixed fixture of DHS+MLS, alongside HemiArthroplasty (HA).
  • Using finite element modeling, researchers analyzed 20 CT scans of femurs to evaluate the performance of these fixation methods in terms of displacement and stress under load.
  • Results showed that while DHS and DHS+MLS had higher stress responses, all fixation methods, including HA and LP, were deemed suitable, with HA and LP recommended for optimal clinical treatment of Pauwels-III fractures.
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