A NiCo alloy particle-decorated TiO nanoarray as an efficient electrocatalyst for nitrite reduction to ammonia.

Electrocatalytic nitrite (NO) reduction (NORR) is a potential environmentally friendly method for producing NH efficiently. Herein, a hybrid catalyst with NiCo alloy particles uniformly decorated on a TiO nanograss array (NiCo-TiO) is reported to display excellent NORR performance. In alkaline media, NiCo-TiO possesses a large NH yield of 18 736.

Tailoring Presynthesized Amorphous SbS Particles Enables High-Efficiency Pure Antimony Sulfide Solar Cells.

At present, hydrothermal deposition techniques are unique to attain high-efficiency antimony sulfide (SbS) solar cells. It is very common that during the mixing of antimony and sulfur sources before the hydrothermal reaction, the solution quickly changes from colorless to yellow due to the formation of amorphous SbS particles. However, the effect of presynthesized SbS particles on the deposition kinetics of SbS absorber layers and the device performance is completely unknown.

Dilated cardiomyopathy signature metabolic marker screening: Machine learning and multi-omics analysis.

Objects: Our aim was to identify changes in the metabolome in dilated cardiomyopathy (DCM) as well as to construct a metabolic diagnostic model for DCM.

Methods: We utilized non-targeted metabolomics with a cross-sectional cohort of age- and sex-matched DCM patients and controls. Metabolomics data were analyzed using orthogonal partial least squares-discriminant analysis (OPLS-DA) and pathway analysis.

An exploration of the interaction, structural characterization and anti-oxidative properties of proanthocyanidin and beta-lactoglobulin complex.

Proanthocyanidin (PC) is with antioxidant, anticancer and neuroprotective effects. Cow's milk beta-lactoglobulin (β-Lg) is reported with higher immunoregulatory activity but lower antioxidative function. In this study, a β-Lg-PC complex was prepared, and the interaction and structural characterization of β-Lg-PC complex were investigated by fluorescence spectral analysis, infrared spectroscopy and molecular docking, etc.

Application of the three-phase T1-derived model in staging liver fibrosis in chronic hepatitis: a comparative study with magnetic resonance elastography.

Objective: This study aims to evaluate the accuracy of a three-phase T1-derived model in staging liver fibrosis in patients with chronic hepatitis, in comparison with magnetic resonance elastography (MRE).

Methods: A total of 174 patients with chronic hepatitis were enrolled. The acquisition of three-phase longitudinal relaxation times (T1-Unenh = A, T1-DLP = B, T1HBP = C) from magnetic resonance enhancement examinations, as well as magnetic resonance elastography (MRE) and liver biopsy information for patients.

Transoral vestibular robotic thyroidectomy in pediatric thyroid disease: 5 case reports.

Background: The safety and feasibility of transoral endoscopic thyroidectomy vestibular approach in pediatric patients has been clinically proven, and its cosmetic results have been recognized by children and their families. However, there are no reports on using transoral robotic in pediatric thyroid surgery. In this study, we report the experience of 5 cases of transoral vestibular robotic thyroidectomy in treating of thyroid disease in children.

Lobopaucinoids A-Q, bioactive terpenoids from the soft coral Lobophytum pauciflorum collected in the South China Sea.

Two undescribed rearranged diterpenoids, lobopaucinoids A and B (1 and 2), along with thirteen undescribed lobane-type diterpenoids lobopaucinoids C-O (3-15) including a C (11) and two C (12 and 13) undescribed norditerpenoids, were isolated from the soft coral Lobophytum pauciflorum Ehrenberg (Sarcophytidae family) collected from Xisha Islands of the South China Sea. Additionally, two undescribed prenyleudesmane-type diterpenoids, lobopaucinoids P and Q (16 and 17), as well as two known lobane diterpenoids (18 and 19), were also obtained. Their structures were elucidated based on comprehensive spectroscopic data, Mosher's method, Mo(OAc) or Rh(OCOCF)-induced circular dichroism experiment, quantum chemical calculations, and single-crystal X-ray diffraction and literature comparison.

Wnt3a Enhances Mesenchymal Stem Cell Engraftment and Differentiation in a Chronic Obstructive Pulmonary Disease Rat Model.

Background: Bone marrow mesenchymal stem cell (BMSC) therapy is a novel approach for treating COPD. However, the difficulty in engraftment and easy clearance of BMSCs in vivo has hindered their clinical application. Hence, exploring effective methods to improve the engraftment and differentiation rates of BMSCs in vivo is urgent.

Facile Synthesis of a CuMoO Nanosheet Array for Electrochemical Reduction of Nitrite to Ammonia in Neutral Solution.

Electrochemical nitrite (NO) is a promising technology for NO removal and a sustainable method for generating valuable ammonia (NH), but this process is intricate and generates other byproducts. In this work, we propose a facile and low-cost method for the preparation of a CuMoO nanosheet array, which can serve as an efficient electrocatalyst for the reduction of NO to NH. The morphology of CuMoO can be adjusted by controlling the synthesis conditions.

Impact of Glycosylation of Apolipoprotein D on Its Interaction with Gold Nanoparticles: Insights from Molecular Dynamics Simulations.

Efficient delivery of nanoparticles (NPs) as carriers for biochemical substances is crucial in various biomedical applications. In this study, we systematically investigate the interactions between glycosylated and nonglycosylated forms of Apolipoprotein D (ApoD) with gold nanoparticles (AuNPs) functionalized with different polymer coatings, including polyethylene glycol (PEG) and zwitterionic polymers. Using all-atom molecular dynamics simulations, we demonstrate that glycosylation significantly enhances the adsorption behavior of ApoD on AuNP surfaces, with the extent of this enhancement being dependent on the type (especially the charge property) of the polymer coatings.

Thermal sensitivity and niche plasticity of generalist and specialist leaf-endophytic bacteria in Mangrove Kandelia obovata.

Leaf endospheres harbor diverse bacterial communities, comprising generalists and specialists, that profoundly affect ecosystem functions. However, the ecological dynamics of generalist and specialist leaf-endophytic bacteria and their responses to climate change remain poorly understood. We investigated the diversity and environmental responses of generalist and specialist bacteria within the leaf endosphere of mangroves across China.

Human induced pluripotent stem cell line XXMUFAi001-A generated from a patient harboring KCNH2 mutation (c. 2690 A>C).

Long QT syndrome type 2 (LQT2), caused by mutations in the KCNH2 gene, is an inherited ion channel disorder associated with sudden death in adolescents. In this study, we generated a patient-specific induced pluripotent stem cell (iPSC) line XXMUFAi001-A using non-integrative Sendai reprogramming technology from an individual carrying a heterozygous point mutation (c.2690 A>C) in KCNH2.

Exploring the Conductive Dynamics of Sb(S,Se)-Based Memristors for Non-Volatile Memory and Neuromorphic Applications.

Advancing the development of novel materials or architectures for random access memories, coupled with an in-depth understanding of their intrinsic conduction mechanisms, holds the potential to transcend the conventional von Neumann bottleneck. In this work, a novel memristor based on the Sb(S,Se) material with an alloy of S and Se was fabricated. A systematic investigation of the correlation between the Se/(S + Se) ratio and memristive performance revealed that Ag/Sb(S,Se)/FTO memristive behavior is uniquely associated with the formation and disruption of anion vacancies and silver filaments.

Polypyrrole-Derived Nitrogen-Doped Tubular Carbon Materials as a Promising Cathode for Aqueous Aluminum-Ion Batteries.

The advantages of aluminum-ion batteries in the area of power source systems are: inexpensive manufacture, high capacity, and absolute security. However, due to the limitations of cathode materials, the capacity and durability of aluminum-ion batteries ought to be further advanced. Herein, we synthesized a nitrogen-doped tubular carbon material as a potential cathode to achieve advanced aqueous aluminum-ion batteries.

[Study on the regularity of acupoint selection and compatibility of acupuncture and moxibustion in the treatment of Parkinson's disease based on complex network analysis].

Objectives: To analyze the regularity of acupoint selection and compatibility of acupuncture and moxibustion for Parkinson's disease (PD) using complex network analysis technology, so as to provide the basis and treatment strategies for clinical acupuncture and moxibustion treatment of PD.

Methods: Relevant literature published in databases of China National Knowledge Infrastructure (CNKI), Wanfang, VIP, PubMed, and Web of Science from the inception to December of 2023 was retrieved. The literature was screened based on inclusion and exclusion criteria to establish a prescription database for acupuncture treatment of PD.

HBV Remodels PP2A Complexes to Rewire Kinase Signaling in Hepatocellular Carcinoma.

Hepatitis B virus (HBV) infections promote liver cancer initiation by inducing inflammation and cellular stress. Despite a primarily indirect effect on oncogenesis, HBV is associated with a recurrent genomic phenotype in hepatocellular carcinoma (HCC), suggesting that it impacts the biology of established HCC. Characterization of the interaction of HBV with host proteins and the mechanistic contributions of HBV to HCC initiation and maintenance could provide insights into HCC biology and uncover therapeutic vulnerabilities.

R-loop formation contributes to mTORC1 activation-dependent DNA replication stress induced by p53 deficiency.

DNA replication stress is a significant contributor to spontaneous DNA damage and genome instability. While the impact of p53 deficiency on increasing DNA replication stress is known, the specific molecular mechanism underlying this phenomenon remains poorly understood. This study explores how p53 deficiency induces DNA replication stress by activating mTORC1 through R-loop formation, which is facilitated by the upregulation of RNR.

Effects of rock content and spatial distribution on the stability of soil rock mixture embankments.

Soil-rock mixture embankments are essential for infrastructure stability, particularly in high-fill construction projects. This study evaluates the effects of rock content and spatial distribution of rock blocks on the bearing capacity, stability, and failure sliding surfaces of SRM embankments through static load model tests. An Equation for Sliding Surface of Block-Rock Content and Distribution was developed to calculate sliding surfaces based on rock content and distribution, and validated it through numerical simulation experiments.

Perovskite-Type CaVO Nanocomposite as High-Performance Anode Material for Lithium-Ion Batteries.

Electric vehicles' rapid development has put higher requirements on the performance of lithium-ion batteries (LIBs). However, the specific capacity of a commercial graphite anode (372 mAh g) has become the bottleneck for further improvement. Therefore, it is urgent to develop novel anode materials with superior performance.

Engineered Biomimetic Nanoparticles-Mediated Targeting Delivery of Allicin Against Myocardial Ischemia-Reperfusion Injury by Inhibiting Ferroptosis.

Background: Cardiac microvascular damage is substantially related with the onset of myocardial ischaemia-reperfusion (IR) injury. Reportedly, allicin (AL) effectively protects the cardiac microvascular system from IR injury. However, the unsatisfactory therapeutic efficacy of current drugs and insufficient drug delivery to the damaged heart are major concerns.

Deposition of Imidazole into Mesoporous Zirconium Metal-Organic Framework for Iodine Capture.

Efficient capture of radioiodine is essential for the protection of the ecological environment and the sustainable development of nuclear energy generation. Metal-organic frameworks (MOFs) and their derivatives provide alternative potential for overcoming the limitations of traditional iodine adsorbents. Herein this work, imidazole (Im) is dispersed into a robust mesoporous zirconium MOF by the heat deposition method, forming a high-uniformity composite .

Crystal structure regulation of trititanium pentoxide for advanced zero-strain lithium storage anode.

Significant advancements have been made in electric vehicles and consumer devices. However, lithium-ion batteries with commercial graphite anodes still face challenges owing to their sluggish lithium-ion kinetics, low lithiation potential, and limited cycle stability. Consequently, there is a considerable research interest in developing new anode materials with rich resources, "zero-strain" characteristics for long-term cycling, and outstanding electrochemical properties.

Cloning and Functional Study of in .

Keng is a diploid perennial grass of triticeae in gramineae. It has strong drought resistance and developed roots that can effectively fix the soil and prevent soil erosion. GDSL lipase or esterases/lipase has a variety of functions, mainly focusing on plant abiotic stress response.