Publications by authors named "Li Shuning"

Bermudagrass ( L.) is a warm-season grass species of significant ecological and economic importance. It is widely utilized in turf management and forage production due to its resilience to drought, salt, and other environmental stresses.

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Background: Obesity, depressive symptoms, and periodontitis are major worldwide health concerns. Despite separate studies on both illnesses, no research has directly examined the link between depressive symptoms and periodontitis in obese people. Given the close correlation between obesity and chronic illnesses, as well as the possibility of a bidirectional impact between depressive symptoms and periodontitis, this study aims to investigate the link between depressive symptoms and periodontitis in an obese population.

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Purpose: To elucidate the genetic basis of primary angle-closure glaucoma (PACG) by identifying pathogenic tissue and critical tissue-specific variants.

Methods: The correlations among PACG susceptibility, axial length (AL), and anterior chamber depth (ACD) were evaluated using meta-analyses. Propensity score matching was utilized on 2161 participants from the Handan Eye Study to determine the risk factors independent of ACD and AL for PACG.

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Objective: Repetitive transcranial magnetic stimulation (rTMS) to the left dorsolateral prefrontal cortex (L-DLPFC) has an improving effect in cognitive function, but it is still not clear in what specific cognitive domains. We here combined a single session of TMS (HF-rTMS/iTBS) with electroencephalography (EEG) to clarify the effects of magnetic stimulation techniques on executive function, working memory, and visuospatial attention in healthy participants, and to investigate the underlying neurophysiological mechanisms.

Methods: Fifty-one healthy participants were randomly assigned to three stimulation groups (HF-rTMS, iTBS, and sham groups).

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Article Synopsis
  • The study investigates the relationship between lipid metabolism and hyperuricemia (HUA) in middle-aged and elderly Chinese individuals, identifying 123 lipids linked to uric acid levels.
  • The prevalence of HUA in the sampled population was found to be 10.4%, with specific lipid types like diacylglycerols and phosphatidylcholines showing a positive association with HUA risk.
  • Dietary intake, such as aquatic products increasing HUA risk and dairy reducing it, alongside the mediation role of retinol-binding protein 4 (RBP4), highlights the complex interplay between lipids, diet, and HUA.
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Cardiometabolic index (CMI) is a novel anthropometric metric that integrates lipid and adiposity characteristics. The correlation between periodontitis development and CMI is ambiguous. The objective of this study was to establish the association between CMI and periodontitis by analyzing data from the NHANES (National Health and Nutrition Examination Survey) database.

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Article Synopsis
  • - Outcomes for patients with relapsed/refractory diffuse large B-cell lymphoma (R/R DLBCL) are generally poor; however, the FDA approved Loncastuximab-teserine (Lonca) based on the LOTIS-2 trial results for those who have undergone at least two prior treatments.
  • - A retrospective study analyzed 187 patients from 21 US centers treated with Lonca, revealing a complete response rate of 14% and an overall response rate of 32%, indicating lower efficacy in a real-world setting compared to the original trial.
  • - Patients in this study had higher risk features, including bulky disease and high-grade B-cell histology, leading to poorer median event-free survival (2.1 months
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Background: Dental informatics is an emerging discipline. Although the accreditation agency governing dental education programs asserts the importance of informatics as foundational knowledge, no well-defined dental informatics courses currently exist within the standard predoctoral dental curriculum. There is a nationwide lack of dental informatics academic programs.

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Article Synopsis
  • The study aimed to compare the 24-hour intraocular pressure (IOP) fluctuations between patients newly diagnosed with ocular hypertension (OHT) and primary open-angle glaucoma (POAG).
  • It involved monitoring IOP every 2 hours over a full day, finding that POAG patients had a steeper increase in IOP during the daytime and a faster decrease at night compared to OHT patients.
  • The findings suggest that larger IOP fluctuations might indicate a higher risk of POAG, but the study has limitations, including relying on a single 24-hour measurement and needing further research for confirmation.
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Purpose: To assess the interactive relationship between blood pressure status and diabetic mellitus (DM) with ganglion cell complex (GCC) thickness in elderly individuals in rural China.

Methods: Participants aged 50 years and older in a rural area of Daxing District, Beijing, were recruited in this study from October 2018 to November 2018. All subjects underwent a comprehensive systemic and ocular examination.

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Objective: To investigate the correlations between choroidal parameters and primary angle-closure suspect (PACS) in different age subgroups.

Methods And Analysis: Participants aged 50 years or older in a rural area of Daxing District, Beijing, were recruited. Swept-source optical coherence tomography was used to measure the choroidal parameters.

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Article Synopsis
  • - The study aimed to create and validate a deep learning model called CMD-Net that can effectively identify and classify mechanisms of angle-closure (AC) in eye images obtained from anterior segment optical coherence tomography (AS-OCT).
  • - Researchers analyzed 11,035 AS-OCT images from 1,455 participants, comparing the deep learning model's performance against human ophthalmologists in classifying AC mechanisms, ultimately showing CMD-Net's superior accuracy with mean AUC scores of up to 0.988.
  • - Findings indicate that CMD-Net may serve as a reliable tool for classifying AC mechanisms in clinical settings, although further testing is necessary to confirm its effectiveness.
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Objective: To investigate the characteristics of beta parapapillary atrophy (β-PPA) in patients with primary angle-closure suspect (PACS).

Methods And Analysis: In total, 215 and 259 eyes with PACS and non-PACS (NPACS), respectively, were enrolled in this observational, cross-sectional study. Stereoscopic fundus and optical coherence tomography images were used to characterise β-PPA; the former was also used to measure the major β-PPA parameters.

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Purpose: To compare the efficacy of morning and evening latanoprost/timolol fixed-combination (LTFC) dosing in patients with primary open-angle glaucoma (POAG) and ocular hypertension.

Methods: In this double-blind, randomized clinical trial, 63 untreated Chinese patients with POAG and ocular hypertension were enrolled. All patients received LTFC and were randomized (1:1) to group 1, morning (8 AM) dosing, or group 2, evening (8 PM) dosing.

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Background: The integration of medical and dental records is gaining significance over the past 2 decades. However, few studies have evaluated the opinions of practicing dentists on patient medical histories. Questions remain on dentists' information needs; their perception of the reliability of patient-reported medical history; satisfaction with the available information and the methods to gather this information; and their attitudes to other options, such as a health information exchange (HIE) network, to collect patient medical history.

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Currently, reported aqueous electrochromic batteries (ECBs) show only limited capacity with insufficient energy density and power density. Such a limitation is naturally imposed by the rationale that the cathode of ECBs stores charge by an ion intercalation/deintercalation mechanism, where the inherent inhibition of ion diffusion and structural collapse of cathode materials through repetitive charge/discharge cycles lead to low areal capacity and unsatisfactory electrochemical performance with short lifetime. Herein, we decouple the dual functions of electrochromism and energy storage in conventional cathodes of ECBs by introducing a polyaniline/triiodide composite cathode that is formed by direct electrolysis of an iodide-based quasi-solid-state aqueous electrolyte during charging.

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Electric vehicles have received extensive attention due to their unique energy efficiency and good emission reduction effects. While a large-scale of electric vehicles are gradually replacing traditional fuel vehicles, it is necessary to ensure the energy efficiency of electric vehicles and the effectiveness of their emission reduction effects. This study conducted a bibliometric analysis of scientific publications on energy efficiency and emission reduction effects of electric vehicles from 2003 to 2022, using a variety of bibliometric tools such as R Studio, biblioshiny and VOSviewer.

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Brentuximab vedotin (BV) in combination with doxorubicin, vinblastine, and dacarbazine (AVD) is increasingly used for frontline treatment of stage III/IV classical Hodgkin lymphoma (cHL). Peripheral neuropathy (PN) was the most common and treatment-limiting side effect seen in clinical trials but has not been studied in a nontrial setting, in which clinicians may have different strategies for managing it. We conducted a multisite retrospective study to characterize PN in patients who received BV + AVD for newly diagnosed cHL.

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Article Synopsis
  • The study evaluates a convolutional neural network (CNN) model for identifying primary angle-closure disease (PACD) and differentiating its stages using anterior segment swept-source OCT images.
  • Participants included a total of 1,141 eyes from different eye centers in China and Singapore, classified into various groups including control and different PACD stages.
  • Results showed that while one classifier performed well in distinguishing PACD stages, others had a drop in accuracy when tested on data from Singapore, indicating varying generalizability of the CNN model.
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Purpose: To investigate the corneal endothelial damage caused by acute primary angle closure (APAC) and related risk factors for severe corneal endothelial cell damage in Chinese subjects.

Methods: In this multicentre retrospective study, 160 Chinese patients (171 eyes) diagnosed with APAC were recruited. Endothelial cell density (ECD) and morphological changes short after APAC were studied.

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Purpose: To investigate whether the retinal nerve fiber layer (RNFL) and ganglion cell complex (GCC) change with optic nerve head (ONH) size in healthy eyes.

Methods: This cross-sectional observational study recruited participants aged ≥50 years. Participants underwent optical coherence tomography-assisted measurements of the peripapillary RNFL and macular GCC and were divided into small, medium, and large ONH groups according to optic disc area (≤1.

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Iodous acid (HIO) has been shown to play a stabilizing role in the nucleation of iodic acid (HIO) (He et al., 2021). However, the stabilization effect and specific stabilizing mechanism of HIO on HIO nucleation under different atmospheric conditions remain unclear.

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Non-syndromic retinitis pigmentosa (NSRP) is a clinically and genetically heterogeneous group of disorders characterized by progressive degeneration of the rod and cone photoreceptors, often leading to blindness. The evolving association of syndromic genes to cause NSRP and the increasing role of intronic variants in explaining missing heritability in genetic disorders present challenges in establishing conclusive clinical and genetic diagnoses. This study sought to identify and validate the causative genetic variant(s) in a 13-year-old male initially diagnosed with NSRP.

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