Light-induced transformation of all-inorganic mixed-halide perovskite nanoplatelets: ion migration and coalescence.

When exposed to light, the colloidal perovskite nanoplatelets (NPLs) in the film can fuse into larger grains, and this phenomenon was thought to be closely related to ion migration. However, the available CsPbBr NPLs are not conducive to directly distinguishing this hypothesis. Herein, we prepare mixed-halide perovskite CsPbBrI NPLs by a ligand-assisted reprecipitation method and investigate the photoluminescence evolution of NPLs under laser irradiation.

Impact of intravenous infusion of lidocaine on intrapulmonary shunt and postoperative cognitive function in patients undergoing one-lung ventilation.

Background: Intravenous infusion of lidocaine as an anesthesia adjuvant can improve patient outcomes, but its impact on intrapulmonary shunt during one-lung ventilation (OLV) has not been clarified.

Objectives: To determine the effect of intravenous lidocaine infusion on intrapulmonary shunt during OLV and postoperative cognitive function in video-assisted thoracoscopic surgery (VATS).

Material And Methods: Sixty patients who underwent OLV for thoracic surgery were randomized to receive intravenous infusion of lidocaine (lidocaine group, n = 30) or normal saline (control group, n = 30) for anesthesia induction.

Homoplantaginin alleviates high glucose-induced vascular endothelial senescence by inhibiting mtDNA-cGAS-STING pathway via blunting DRP1-mitochondrial fission-VDAC1 axis.

Vascular endothelial senescence is a major risk factor for diabetic vascular complications. Abnormal mitochondrial fission by dynamically related protein 1 (DRP1) accelerates vascular endothelial cell senescence. Homoplantaginin (Hom) is a flavonoid in Salvia plebeia R.

Improving AGB estimations by integrating tree height and crown radius from multisource remote sensing.

Precise estimation of forest above ground biomass (AGB) is essential for assessing its ecological functions and determining forest carbon stocks. It is difficult to directly obtain diameter at breast height (DBH) based on remote sensing imagery. Therefore, it is crucial to accurately estimate the AGB with features extracted directly from RS.

Balancing Flexible Side Chains on 2D Conjugated Acceptors Enables High-Performance Organic Solar Cell.

Balancing the rigid backbones and flexible side chains of light-harvesting materials is crucially important to reach optimized intermolecular packing, micromorphology, and thus photovoltaic performance of organic solar cells (OSCs). Herein, based on a distinctive CH-series acceptor platform with 2D conjugation extended backbones, a series of nonfullerene acceptors (CH-6F-Cn) are synthesized by delicately tuning the lengths of flexible side chains from n-octyl to n-amyl. A systemic investigation has revealed that the variation of the side chain's length can not only modulate intermolecular packing modes and crystallinity but also dramatically improve the micromorphology of the active layer and eventual photovoltaic parameters of OSCs.

Continuous Nanomanufacturing of Inorganic Lead Halide Perovskite Nanocrystals with High-Concentration Precursors.

The microscale flow preparation scheme has been widely used in the preparation of inorganic perovskite nanocrystals (NCs). It is considered to be the most promising method for large-scale production. Recently, it has been suggested that increasing the precursor concentration can further improve efficiency, but there is still a lack of understanding of high-concentration synthesis.

Propofol modulates neural dynamics of thalamo-cortical system associated with anesthetic levels in rats.

Unlabelled: The thalamocortical system plays an important role in consciousness. How anesthesia modulates the thalamocortical interactions is not completely known.  We simultaneously recorded local field potentials(LFPs) in thalamic reticular nucleus(TRN) and ventroposteromedial thalamic nucleus(VPM), and electrocorticographic(ECoG) activities in frontal and occipital cortices in freely moving rats ( = 11).

Propeller vs Quasi-Planar 6-Cantilever Small Molecular Platforms with Extremely Two-Dimensional Conjugated Extension.

Two exotic 6-cantilever small molecular platforms, characteristic of quite different molecular configurations of propeller and quasi-plane, are established by extremely two-dimensional conjugated extension. When applied in small molecular acceptors, the only two cases of CH25 and CH26 that could contain six terminals and such broad conjugated backbones have been afforded thus far, rendering featured absorptions, small reorganization and exciton binding energies. Moreover, their distinctive but completely different molecular geometries result in sharply contrasting nanoscale film morphologies.

IKVAV peptide-containing hydrogel decreases fibrous scar after spinal cord injury by inhibiting fibroblast migration and activation.

Fibrous scar is one of the major factors that hinder functional recovery in patients with spinal cord injury (SCI). Studies have shown that the laminin α1 peptide chain ile-les-val-ala-Val (IKVAV) promoted axonal growth and motor function recovery in rats after SCI. However, whether IKVAV could ameliorate SCI via reducing the formation of fibrous scar was not clear.

Effects of dexmedetomidine on dynamic lung compliance in general anesthesia with desflurane: A randomized controlled study.

Objective: The aim of this study was to evaluate the effect of dexmedetomidine on lung compliance in patients under general anesthesia with desflurane.

Methods: This prospective, randomized, double-blind, controlled trial included 51 patients who received general anesthesia undergoing lower limb fracture surgery. Participants were assigned to either the experimental (loading dose of 0.

Dynamics of macroplastics and microplastics formed by biodegradable mulch film in an agricultural field.

Conventional plastic mulch brings agronomic and economic benefits to crop production, but a large amount of plastic waste amasses when the mulch is removed from the fields after harvest. Soil-biodegradable plastic mulch (BDM) has emerged as a promising alternative to conventional plastic mulch as it can be tilled into the soil after harvest, thereby alleviating disposal problems. However, direct evidence on complete degradation of biodegradable mulch under natural conditions is still lacking.

Intraoperative right heart function with individualized mechanical ventilation in laparoscopic surgery with Trendelenburg positioning: A randomized-controlled study.

Background: The intraoperative effects of mechanical ventilation with individualized positive end-expiratory pressure guided by dynamic compliance on right heart function remains undefined.

Objectives: To investigate whether individualized ventilation is superior to standard ventilation in protecting the right heart during abdominal laparoscopic surgery in the Trendelenburg position.

Methods: Forty patients who underwent abdominal laparoscopic surgery were randomly divided into two groups: Group T (titrimetric positive end-expiratory pressure [PEEP]) and Group I (intentional PEEP, 5 cmHO).

Altered functional and directed connectivity in propofol-induced loss of consciousness: A source-space resting-state EEG study.

Objective: General anesthesia might disrupt neuronal network communications measured by functional connectivity (FC; undirected connectivity) and directional information flow (directed connectivity). We sought to characterize the state-dependent effects of propofol on cortico-cortical undirected and directed FC.

Methods: We collected 256-channel high-density EEGs from 14 patients undergoing surgery while awake (AWA) or in propofol-induced moderate sedation (SED) or loss of consciousness (LOC) states.

Management of Donor and Acceptor Building Blocks in Dopant-Free Polymer Hole Transport Materials for High-Performance Perovskite Solar Cells.

The dominant hole transport material (HTM) in state-of-the-art perovskite solar cells (PSCs) is Spiro-OMeTAD, which needs to be doped using hydrophilic dopants to improve its hole mobility and conductivity, resulting in inferior device stability. Here, we propose an effective molecular design strategy to construct dopant-free polymer HTMs by selecting four structurally related polymers and investigating their structure-property relationship. It is found that the donor and acceptor units with longitudinal conjugate extension, such as BDT-T and BDD, could not only enhance the planarity of the conjugated polymer backbone and tune the energy levels but also promote the face-on orientation, resulting in superior charge extraction and transport.

Synthesis, Biological Evaluation, and Molecular Docking Studies of Hydrazones as Novel Xanthine Oxidase Inhibitors.

A series of hydrazones, 2-cyano-N'-(4-diethylamino-2-hydroxybenzylidene)acetohydrazide (1), N'-(5-bromo-2-hydroxy-3-methoxybenzylidene)-3-chlorobenzohydrazide monohydrate (2·H2O), N'-(2-hydroxy-3-methylbenzylidene)-4-nitrobenzohydrazide (3), and N'-(2-hydroxy-3-trifluoromethoxybenzylidene)-4-nitrobenzohydrazide (4), were prepared and structurally characterized by elemental analysis, IR and 1H NMR spectra, and single crystal X-ray determination. Xanthine oxidase inhibitory activities of the compounds were studied. Among the compounds, 2-cyano-N'-(4-diethylamino-2-hydroxybenzylidene)acetohydrazide shows the most effective activity.

Intelligent Algorithm-Based Echocardiography to Evaluate the Effect of Lung Protective Ventilation Strategy on Cardiac Function and Hemodynamics in Patients Undergoing Laparoscopic Surgery.

The aim of this study was to analyze the effect of optimal pulmonary compliance titration of PEEP regimen on cardiac function and hemodynamics in patients undergoing laparoscopic surgery. 120 patients undergoing elective laparoscopic radical resection of colorectal cancer were included as the study subjects and randomly divided into the experimental group ( = 60) and the control group ( = 60). The control group had a fixed positive end-expiratory pressure (PEEP) = 5 cmHO.

Achieving over 18 % Efficiency Organic Solar Cell Enabled by a ZnO-Based Hybrid Electron Transport Layer with an Operational Lifetime up to 5 Years.

Although organic solar cells (OSCs) have delivered an impressive power conversion efficiency (PCE) of over 19 %, most of them demonstrated rather limited stability. So far, there are hardly any effective and universal strategies to improve stability of state-of-the-art OSCs. Herein, we developed a hybrid electron-transport layer (ETL) in inverted OSCs using ZnO and a new modifying agent (NMA), and significantly improved the stability and PCEs for all the tested devices.

Dezocine relieves the postoperative hyperalgesia in rats through suppressing the hyper-action of Akt1/GSK-3β pathway.

The relieving role of dezocine in pain after surgery was previously reported, while the potential mechanism was not completely clear. Therefore, the current research probed into the regulatory mechanism of dezocine in pain after surgery. A postoperative pain model was established by performing plantar incision surgery on the juvenile Sprague-Dawley rats.

Impact of Succinylcholine vs. Rocuronium on Apnea Duration for Rapid Sequence Induction: A Prospective Cohort Study.

Objective: The present study aimed to evaluate the impact of 1.5 mg/kg succinylcholine or 1.2 mg/kg rocuronium, vs.

Macro- and microplastic accumulation in soil after 32 years of plastic film mulching.

Plastic film mulch (PFM) is a double-edged-sword agricultural technology, which greatly improves global agricultural production but can also cause severe plastic pollution of the environment. Here, we characterized and quantified the amount of macro- and micro-plastics accumulated after 32 years of continuous plastic mulch film use in an agricultural field. An interactive field trial was established in 1987, where the effect of plastic mulching and N fertilization on maize yield was investigated.

Identification of independent risk factors for intraoperative gastroesophageal reflux in adult patients undergoing general anesthesia.

Background: Gastroesophageal reflux (GER) affects up to 20% of the adult population and is defined as troublesome and frequent symptoms of heartburn or regurgitation. GER produces significantly harmful impacts on quality of life and precipitates poor mental well-being. However, the potential risk factors for the incidence and extent of GER in adults undergoing general anesthesia remain unclear.

Transversus abdominis plane block provides effective and safe anesthesia in the cesarean section for an amyotrophic lateral sclerosis parturient: A case report.

Rationale: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease with the fatal course of muscle weakness. The published experience of anesthesia management in the cesarean section with ALS parturient is scant.

Patient Concerns: A 34-year-old woman was admitted to our center complaining of obvious dysphagia together with atrophy and weakness of quadriceps at 24 weeks of her pregnancy.

Exosomes Derived from ADSCs Attenuate Sepsis-Induced Lung Injury by Delivery of Circ-Fryl and Regulation of the miR-490-3p/SIRT3 Pathway.

Sepsis-induced lung injury is a clinical syndrome characterized by injury of alveolar epithelium cells (AECs). Previous investigations illustrate that exosomes secreted from adipose-derived stem cells (ADSCs) have therapeutic effects in a variety of disease treatments, but roles and mechanisms regarding ADSC-derived exosomes in sepsis-induced lung injury are unclear. In this study, high-throughput sequencing was used to explore the molecular delivery of ADSC exosomes.

Concurrently Improved , Fill Factor, and Stability in a Ternary Organic Solar Cell Enabled by a C-Shaped Non-fullerene Acceptor and Its Structurally Similar Third Component.

A ternary strategy is recognized as a promising approach that enjoys both the simplicity of fabrication conditions and potential to improve performance in organic solar cells. Herein, a C-shaped narrow band gap non-fullerene acceptor GL1 with a C symmetry based on a new core was designed and synthesized. A power conversion efficiency (PCE) of 11.