Publications by authors named "Li Ming Jia"

Article Synopsis
  • Diabetes raises the risk of severe COVID-19 outcomes, with Cathepsin L (CTSL) linked to complications like nephropathy and retinopathy.
  • Research shows that higher blood levels of CTSL in diabetic patients enhance SARS-CoV-2 infection, influenced by chronic and acute hyperglycemia.
  • Studies indicate that elevated glucose levels, not insulin, increase CTSL activity and promote virus infection, as demonstrated through experiments with human and mouse cells.
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Carbon supplementation strategies still have certain practical application constraints. Zn/Fe-based metal-organic frameworks (MOFs) nanoparticles that which are not toxic to Scenedesmus obliquus were successfully introduced into microalgal solutions to overcome low CO solubility. The maximum specific surface area of MOFs reached 342.

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Neutral aqueous organic redox flow batteries (AORFBs) hold the potential to facilitate the transition of renewable energy sources from auxiliary to primary energy, the commercial production of anolyte materials still suffers from insufficient performance of high-concentration and the high cost of the preparation problem. To overcome these challenges, this study provides a hydrothermal synthesis methodology and introduces the charged functional groups into hydrophobic naphthalene diimide cores, and prepares a series of high-performance naphthalene diimide anolytes. Under the synergistic effect of π-π stacking and H-bonding networks, the naphthalene diimide exhibits excellent structural stability and the highest water solubility (1.

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A series of chalcogenophene viologens (, , and ) as anolytes for neutral aqueous organic redox flow batteries (AORFBs) via a combination of chalcogenophenes (furan, thiophene, and selenophene) and viologens are reported. The chalcogenophene viologens showed narrow HOMO-LUMO energy gap, high solubility, and stable electrochemical properties. Compared with the parent , the introduction of π-conjugated chalcogenophene groups reduced the redox potential and enhanced the stability of their free radical state, which endowed the -based AORFBs with a higher theoretical battery voltage of 1.

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The spike (S) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an important target for vaccine and drug development. However, the rapid emergence of variant strains with mutated S proteins has rendered many treatments ineffective. Cleavage of the S protein by host proteases is essential for viral infection.

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A new hybrid system is proposed to capture CO as well as generate electricity with the low CO inlet condition of confined space. Within the system, a novel photocatalytic porous framework coated by g-CN/TiO is prepared to avoid the inhibition of microalgae growth caused by the direct addition of photocatalyst. Under 0.

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We explored the coupling effects of water and nitrogen in furrow irrigation on the growth and absorption and utilization of water and nitrogen in young poplar trees (triploid ), under three irrigation levels (W, W, W; when the soil water potential of 40 cm under the ditch reaches -20, -33 and -45 kPa respectively, irrigate), four N application levels (N, N, N and N; the fertilization amount was 120, 190, 260 and 0 kg·hm·a), and natural conditions (CK). Based on the growth status of trees, the optimal combination of irrigation level and nitrogen application rate under furrow irrigation conditions was determined. The results showed that WN (high water and low fertilizer; soil water potential threshold for initiating irrigation was -20 kPa and N application rate was 120 kg·hm·a) had the strongest effect on the stand productivity, with a value of 33.

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Article Synopsis
  • A field experiment was conducted using surface drip irrigation to assess how different levels of water and nitrogen influenced poplar tree growth and soil nitrogen content over two growing seasons.
  • Three irrigation levels and three nitrogen addition levels were tested, leading to significant increases in tree diameter, height, and stem volume, particularly when both water and nitrogen were maximally applied.
  • Increases in total nitrogen content in the soil were observed, showing a strong positive correlation with tree growth, although irrigation alone did not significantly impact tree size.
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To examine the reproduction fitness coefficients and individual-level fitness of Toona ciliata var. pubescens, their sexual reproduction and natural regeneration were investigated during 2006-2016, with four natural populations in Jiulianshan National Reserve as test objects. The results showed that there were only 2-10 trees for the natural populations of T.

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Exacerbation of pain by chronic stress and comorbidity of pain with stress-related psychiatric disorders, including anxiety and depression, represent significant clinical challenges. However, the underlying mechanisms still remain unclear. Here, we investigated whether chronic forced swim stress (CFSS)-induced exacerbation of neuropathic pain is mediated by the integration of stress-affect-related information with nociceptive information in the central nucleus of the amygdala (CeA).

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Improper treatment of organic waste may result in environmental pollution and harm to plant growth due to the high concentration of phytotoxin. Composting has widely been used for recycling organic waste and reducing phytotoxin to improve soil properties. Assessing the phytotoxicity grades of compost products is essential for achieving high quality compost to guarantee its marketability.

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To study the variation of PM2.5 concentration in scenic recreational plantations and its response to meteorological factors, and to analyze the regulation effect of different stands on PM2.5 concentration, in the summer, autumn and winter of 2013, PM2.

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Dibromoacetic acid (DBAA), a haloacetic acid found in drinking water as a disinfection by-product, can cause many adverse effects, including immunotoxicity. In a previous study, we confirmed that DBAA can induce obvious immunotoxicity in mice but that the underlying mechanisms are not clearly understood. In our current study, we confirmed that DBAA induced cytotoxicity and apoptosis in thymocytes isolated from mice by a range of DBAA concentrations (0, 5, 10, 20, or 40 μM).

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A field experiment was conducted to investigate the effects of fertilization methods, i.e., drip (DF) and furrow fertilization (GF), and nitrogen (N) application rates (25, 50, 75 g N · plant(-1) · time(-1)) on the dynamics of soil N vertical migration in a Populus x euramericana cv.

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In this work, the influence of temperature and humidity environment on the water vapor adsorption capacity and effective thermal conductivity of silica nano-porous material is conducted within a relative humidity range from 15% to 90% at 25 °C, 40 °C and 55 °C, respectively. The experiment results show that both the temperature and relative humidity have significant influence on the adsorption capacity and effective thermal conductivity of silica nano-porous materials. The adsorption capacity and effective thermal conductivity increase with humidity because of the increases of water vapor concentration.

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Taking Populus tomentosa as an example, a methodology called elution-weighing-particle size-analysis (EWPA) was proposed to evaluate quantitatively the ability of retaining fine particulate matter (PM2.5, diameter d ≤ 2.5 μm) and atmospheric particulate matter by plant leaves using laser particle size analyzer and balance.

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Based on the observed data of triploid Populus tomentosa root distribution, a one-dimensional root water uptake model was proposed. Taking the root water uptake into account, the soil water dynamics in triploid P. tomentosa root zone under subsurface drip irrigation was simulated by using HYDRUS model, and the results were validated with field experiment.

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By combination of two defect structures with positive and negative birefringence, we design a holey fiber with a beat length that is less sensitive to wavelength. The influence of different structural parameters on birefringence of holey fiber is calculated by the finite-difference beam propagation method. A stable beat length can be achieved at some given wavelength window by adjusting the parameters.

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Activation of N-methyl-d-aspartate (NMDA) receptors in the spinal dorsal horn has been shown to be essential for the initiation of central sensitization and the hyperexcitability of dorsal horn neurons in chronic pain. However, whether the spinal NR2B-containing NMDA (NMDA-2B) receptors are involved still remains largely unclear. Using behavioral test and in vivo extracellular electrophysiological recording in L5 spinal nerve-ligated (SNL) neuropathic rats, we investigate the roles of spinal cord NMDA-2B receptors in the development of neuropathic pain.

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Objective: An attempt was made to provide a better insight into endoscopic and histological features and to enhance the understanding of the diagnostic value of colonoscopy combined with biopsy for colonic Crohn's disease.

Methods: As presented in our 27 cases of colonic Crohn's disease (Crohn's colitis), the endoscopic findings and histological changes of biopsy specimens were analyzed. As collated with correspondent results of biopsy and surgical specimens, the diagnostic accuracy of endoscopy was evaluated.

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Objective: An attempt was made to provide a better insight into endoscopic and histological features and/or problems encountered when establishing a diagnosis of colonic Crohn's disease (Crohn's colitis).

Methods: As presented in our 27 cases with Crohn's colitis, the endoscopic findings and histological changes of biopsy specimens were summarized. As collated with correspondent results of biopsy and surgical specimens, the diagnostic accuracy of endoscopy was evaluated.

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Background: An increasing incidence of Crohn's disease has been found in China in recent years. Our study has been focused on evaluating the diversity of the clinical manifestations of Crohn's disease in order to improve early diagnostic accuracy and therapeutic efficacy.

Methods: Thirty patients with active Crohn's disease were enrolled and their clinical data, including diagnostic and therapeutic results, were analyzed.

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