Publications by authors named "Li Luming"

Background: Abnormal rapid eye movement (REM) sleep, including REM sleep behavior disorder (RBD) and reduced REM sleep, is common in Parkinson's disease (PD), highlighting the importance of further study on REM sleep. However, the biomarkers of REM disturbances remain unknown, leading to the lack of REM-specific neuromodulation interventions.

Objective: This study aims to investigate the neurophysiological biomarkers of REM disturbance in parkinsonian patients.

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Aqueous biphasic systems (ABSs) with water-in-salt electrolytes are gaining significant attention for their role in aqueous biphasic interphase studies, particularly in energy storage devices. Aqueous salt-salt biphasic electrolytes are considered a promising alternative to replace traditional liquid electrolytes commonly used in battery technologies, for example, membrane-less redox flow batteries, owing to their low cost and high ionic conductivity. However, the stability of the interphase over time must be considered, as it can impact the long-term electrochemical performance in various applications.

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In the quest to replace fossil fuels and reduce carbon dioxide emissions, developing energy technologies based on clean catalytic processes is fundamental. However, the cost-effectiveness of these technologies strongly relies on the availability of efficient catalysts made of abundant elements. Herein, this study presents a one-step hydrothermal method to obtain a series of NiSe nanoparticles with a layer of amorphous selenium on their surface.

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Deep brain stimulation (DBS) is an effective treatment for neurological disorders, and accurately reconstructing the DBS lead trajectories is crucial for MRI compatibility assessment and surgical planning. This paper presents a novel fully automated framework for reconstructing DBS lead trajectories from postoperative CT images. The leads were first segmented by thresholding, but would be fused together somewhere.

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Among renewable energy technologies, particular attention is paid to electrochemically transforming methanol into valuable formate and storing energy into supercapacitors. In this study, we detailed a simple colloidal-based protocol for synthesizing a series of alloy nanoparticles with tuned Ni/Co atomic ratios, thereby optimizing their electrochemical performance. With the addition of 1 M methanol in 1 M KOH, the optimized composition was able to electrochemically produce formate at 0.

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Developing energy- and time-efficient strategies to derive high-performance non-precious electrocatalysts for anodic oxygen evolution reaction (OER), especially stably working at industrial-demanding current density, is still a big challenge. In this work, a concise molten salt erosion scenario was devised to rapidly modulate the smooth surface of the commercial NiMo foam substrate into the rough, electronically coupled, and hierarchically porous Ni/Fe/Mo(oxy)hydroxide catalyst layer assembled by the nanosphere array. This self-supported catalyst is super-hydrophilic for the alkaline electrolyte and distinguished by a balanced Mo leaching/surface-readsorption process to tune the metal d band center and electronic perturbation.

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Telemedicine and video-based diagnosis have raised significant concerns regarding the protection of facial privacy. Effective de-identification methods require the preservation of diagnostic information related to normal and pathological facial movements, which play a crucial role in the diagnosis of various movement, neurological, and psychiatric disorders. In this work, we have developed FaceMotionPreserve , a deep generative model-based approach that transforms patients' facial identities while preserving facial dynamics with a novel face dynamic similarity module to enhance facial landmark consistency.

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Background: The study focuses on thermal management in tumor-treating fields (TTFields) therapy, crucial for patient compliance and therapeutic effectiveness. TTFields therapy, an established treatment for glioblastoma, involves applying alternating electric fields to the brain. However, managing the thermal effects generated by electrodes is a major challenge, impacting patient comfort and treatment efficiency.

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Aims: To predict the vagus nerve stimulation (VNS) efficacy for pediatric drug-resistant epilepsy (DRE) patients, we aim to identify preimplantation biomarkers through clinical features and electroencephalogram (EEG) signals and thus establish a predictive model from a multi-modal feature set with high prediction accuracy.

Methods: Sixty-five pediatric DRE patients implanted with VNS were included and followed up. We explored the topological network and entropy features of preimplantation EEG signals to identify the biomarkers for VNS efficacy.

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Background: Although previous studies have suggested a possible association between bone mineral density (BMD) and intervertebral disc degeneration (IDD), the causal relationship between them remains unclear. Evidence from accumulating studies indicates that they might mutually influence one another. However, observational studies may be affected by potential confounders.

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Sleep disturbances profoundly affect the quality of life in individuals with neurological disorders. Closed-loop deep brain stimulation (DBS) holds promise for alleviating sleep symptoms, however, this technique necessitates automated sleep stage decoding from intracranial signals. We leveraged overnight data from 121 patients with movement disorders (Parkinson's disease, Essential Tremor, Dystonia, Essential Tremor, Huntington's disease, and Tourette's syndrome) in whom synchronized polysomnograms and basal ganglia local field potentials were recorded, to develop a generalized, multi-class, sleep specific decoder - BGOOSE.

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Background: Sleep fragmentation is a persistent problem throughout the course of Parkinson's disease (PD). However, the related neurophysiological patterns and the underlying mechanisms remained unclear.

Method: We recorded subthalamic nucleus (STN) local field potentials (LFPs) using deep brain stimulation (DBS) with real-time wireless recording capacity from 13 patients with PD undergoing a one-night polysomnography recording, 1 month after DBS surgery before initial programming and when the patients were off-medication.

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Article Synopsis
  • Idiopathic scoliosis is a condition affecting children's physical and mental health, with a study conducted in Yunnan Province, China, to determine its prevalence and associated miRNA profiles.
  • The study screened 84,460 students from ages 7 to 19, finding an overall prevalence of 1.10%, with higher rates in females (1.32%) than in males (0.87%), peaking at age 13.
  • Genetic analysis revealed 56 upregulated and 153 downregulated exosome-derived miRNAs in patients with idiopathic scoliosis, which could help understand the condition better and potentially lead to new diagnostic methods.
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Demand for mental health services has dramatically increased in recent years, raising concerns about the availability of service providers to meet these increased needs. One approach to expanding access to care is the use of highly qualified board-certified psychiatric pharmacists (BCPPs). However, the implementation of programs for integrating BCPPs has not been well characterized in community mental health settings.

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Renewable electricity-powered nitrate/carbon dioxide co-reduction reaction toward urea production paves an attractive alternative to industrial urea processes and offers a clean on-site approach to closing the global nitrogen cycle. However, its large-scale implantation is severely impeded by challenging C-N coupling and requires electrocatalysts with high activity/selectivity. Here, cobalt-nanoparticles anchored on carbon nanosheet (Co NPs@C) are proposed as a catalyst electrode to boost yield and Faradaic efficiency (FE) toward urea electrosynthesis with enhanced C-N coupling.

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Article Synopsis
  • Advanced lithium-ion batteries for implantable medical devices and spacecraft face challenges at zero-volt storage (ZVS), including potential Cu dissolution and solid-electrolyte interphase (SEI) degradation at 37 °C.
  • By adjusting the dosage of LiCoO cathode additives, researchers demonstrated a way to keep the anode potential under control, maintaining it below 2.0 V and improving capacity retention.
  • The study identified the limiting conditions for long-term ZVS use and established an optimized potential range, achieving the highest capacity retention ratios recorded while minimizing Cu dissolution and SEI degradation.
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Magnetic superhydrophobic materials have broad application prospect in oil-water separation. In this study, a magnetic and superhydrophobic aerogel with lamellar structure was successfully prepared using cellulose nanofibrils (CNF) as the skeleton, FeO as the magnetic ion, 1H, 1H, 2H, 2H trialkylfluorooctane triethoxysilane (FS) and 3-(2-aminoethyl amino)-propyl trimethoxysilane (AS) as the combined modifier. The prepared aerogel shows lower density (38.

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Electrochemical upgrading methanol into value-added formate at the anode in alkaline media enables the boosting production of hydrogen fuel at the cathode with saved energy. To achieve such a cost-effective and efficient electrocatalytic process, herein this work presents a Mn-doped nickel iron layered double hydroxides supported on nickel foam, derived from a simple hydrothermal synthesis. This developed electrocatalyst could act as an efficient bifunctional electrocatalyst for methanol-to-formate with a high faradaic efficiency of nearly 100 %, and for hydrogen evolution reaction, at an external potential of 1.

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Seawater electrolysis holds tremendous promise for the generation of green hydrogen (H). However, the system of seawater-to-H faces significant hurdles, primarily due to the corrosive effects of chlorine compounds, which can cause severe anodic deterioration. Here, a nickel phosphide nanosheet array with amorphous NiMoO layer on Ni foam (NiP@NiMoO/NF) is reported as a highly efficient and stable electrocatalyst for oxygen evolution reaction (OER) in alkaline seawater.

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Article Synopsis
  • Electrochemical conversion of nitrite to green ammonia addresses nitrogen cycle issues, but slow reaction rates and the need for effective catalysts are major challenges.
  • The study highlights a new catalyst: molybdenum doped cobalt oxide nanoarray on titanium mesh (Mo-CoO/TM), which achieves a Faradaic efficiency of 96.9% and a NH yield of 651.5 μmol h cm at -0.5 V.
  • Density functional theory shows that molybdenum enhances electron distribution and NO adsorption on cobalt, improving catalytic performance, and the Mo-CoO/TM system shows potential for practical applications in batteries.
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Seawater electrolysis is gaining recognition as a promising method for hydrogen production. However, severe anode corrosion caused by the high concentration of chloride ions (Cl) poses a challenge for the long-term oxygen evolution reaction. Herein, an anti-corrosion strategy of oxalate anions intercalation in NiFe layered double hydroxide on nickel foam (NiFe-CO LDH/NF) is proposed.

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Article Synopsis
  • * The presence of chlorine in seawater can corrode catalysts used in the electrolysis process, impacting their durability.
  • * Incorporating tungstate (WO) into NiFe layered double hydroxides (LDH) enhances the efficiency and stability of oxygen generation, achieving nearly perfect efficiency and minimal chlorine byproducts during prolonged tests.
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