Couple-Group Consensus of Cooperative-Competitive Heterogeneous Multiagent Systems: A Fully Distributed Event-Triggered and Pinning Control Method.

This article discusses the couple-group consensus for heterogeneous multiagent systems via event-triggered and pinning control methods. Considering cooperative-competitive interaction among the agents, a novel group consensus protocol is designed. As inducing the time-correlation threshold function, a class of fully distributed event-triggered conditions without depending on any global information is proposed.

[Therapeutic effect of photodynamic treatment for psoriasis vulgaris in guinea pigs].

Objective: To observe the efficacy of 5-aminolevulinic acid photodynamic therapy (ALA-PDT) for treating psoriasis vulgaris in guinea pigs.

Methods: Experimental psoriasis vulgaris was induced in guinea pigs by application of 5% propranolol on the ear skin. After dressing of the skin lesion with 20% ALA solution for 4 h, the lesions were irradiated with a semiconductor laser at the wavelength of 635 nm and energy density of 12 J/cm(2).

Large-scale asymmetric synthesis of the bioprotective agent JP4-039 and analogs.

JP4-039 is a novel nitroxide conjugate capable of crossing lipid bilayer membranes and scavenging reactive oxygen species (ROS). An efficient and scalable one-pot hydrozirconation-transmetalation-imine addition methodology has been developed for its asymmetric preparation. Furthermore, this versatile methodology allows for the synthesis of cyclopropyl and fluorinated analogs of the parent lead structure.

Copper-catalyzed enantioselective intramolecular conjugate addition/trapping reactions: synthesis of cyclic compounds with multichiral centers.

The Cu-catalyzed enantioselective conjugate addition of dialkylzinc to bis-alpha,beta-unsaturated carbonyl compounds followed by the intramolecular trapping of the zinc enolate in the presence of chiral phosphoramidite ligands was investigated. Cyclic and heterocyclic compounds with multichiral centers were formed as a mixture of two diastereomers with excellent diastereoselectivities (up to 99:1) and enantioselectivities (up to 94 % ee, ee=enantiomeric excess). The stereochemistry was determined to be trans,trans for the major products and trans,cis for the minor products.