Publications by authors named "Li Jiang Ze"
Research Progress of nucleic acid delivery vectors for gene therapy.
Biomed Microdevices
January 2020
Article Synopsis
- Gene therapy shows promise for treating cancers and hereditary diseases, but the effective delivery of nucleic acids like DNA and siRNA is challenging due to their degradation in the body.
- Currently, delivery vectors are categorized into viral (high efficiency but safety concerns) and non-viral (lower immunogenicity and easier to produce).
- The review evaluates existing delivery systems and highlights a new delivery method using RNTs, detailing their properties, delivery process, and current applications.