Publications by authors named "Li Hui Lai"
Article Synopsis
- A multi-day haze event took place in Shijiazhuang from November 18-26, 2014, where researchers analyzed air quality using a single particle aerosol mass spectrometer (SPAMS) to identify pollutant sources.
- The study identified seven primary sources of fine particulate matter in the air, including coal combustion, industrial activities, vehicle emissions, dust, biomass burning, secondary inorganic sources, and dining activities, with organic carbon (OC) and elemental carbon (EC) being the most significant contributors.
- During the haze, the concentration of ammonium (NH4+) and other pollutants like sulfates (SO4-) and nitrates (NO3-) rose sharply, particularly under stagnant weather conditions, leading to a high degree of
Colorectal cancer (CRC) is one of the leading cancer-related causes of death in the world. Recently, downregulation of microRNA-143 (miR-143) has been observed in CRC tissues. Here in this study, we found that miR-143 expression was downregulated both in CRC patients' blood samples and tumor specimens.
View Article and Find Full Text PDF[The expression pattern and possible function of microRNA-34a in neurons].
Fen Zi Xi Bao Sheng Wu Xue Bao
June 2009
Using Northern blotting, ISH and FISH, we demonstrated miR-34a expresses with aging in the brain of rhesus monkey and rat. Correspondingly, the same trend was found in the primary cultures of cortical neurons. Moreover, we found that induction of miR-34a led to neuronal apoptosis by targeting BCL-2.
View Article and Find Full Text PDF[Knockdown and overexpression of miR-219 lead to embryonic defects in zebrafish development].
Fen Zi Xi Bao Sheng Wu Xue Bao
October 2008
MicroRNAs (miRNAs) are important post-transcriptional modulators of gene expression, which have been implicated in many physiological and pathological processes. In this study, we found that miR-219 expressed since early segmentation stages (16s) in spinal cord and mid-, hindbrain in zebrafish using Northern blotting and whole mounts ISH technologies. Moreover, knockdown or overexpression of miR-219 led to specific embryonic defects.
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