Fresh bamboo juice regulates the diversity of intestinal microflora in mice by promoting the function of ILC2 cells to mediate intestinal protection.

Background And Aim: Ulcerative colitis (UC) is a growing global health concern, with current treatments facing challenges like drug dependence and side effects. Fresh bamboo juice (FBJ), known for its antimicrobial and potential immune-modulating properties, has shown promise as a natural therapeutic agent. The present study aimed to explore the protective effects of FBJ against colitis and further analyze the changes of gut microbiota composition, metabolite profiles, and underlying immune mechanisms.

Analysis of the acoustoelectric response of SAW gas sensors using a COM model.

Surface acoustic wave (SAW) gas sensors based on the acoustoelectric effect exhibit wide application prospects for in situ gas detection. However, establishing accurate models for calculating the scattering parameters of SAW gas sensors remains a challenge. Here, we present a coupling of modes (COM) model that includes the acoustoelectric effect and specifically explains the nonmonotonic variation in the center frequency with respect to the sensing film's sheet conductivity.

Sexual violence against women remains problematic and highly prevalent around the world.

Background: Sexual violence is far more prevalent in most societies than is usually suspected in daily life. However, no study has systematically summarized the global prevalence rate and the major outcomes of sexual violence against women.

Methods: We directed a wide-raging search in the PubMed, Embase, and Web of Science, catalogs since the beginning to December 2022 for relevant reports about the incidence of sexual fighting touching females.

Optimal postoperative surveillance strategies for cancer survivors with gastric neuroendocrine carcinoma based on individual risk: a multicenter real-world cohort study.

Background: The best follow-up strategy for cancer survivors after treatment should balance the effectiveness and cost of disease detection while detecting recurrence as early as possible. Due to the low incidence of gastric neuroendocrine carcinoma and mixed adenoneuroendocrine carcinoma [G-(MA)NEC], high-level evidence-based follow-up strategies is limited. Currently, there is a lack of consensus among clinical practice guidelines regarding the appropriate follow-up strategies for patients with resectable G-(MA)NEC.

Highly Sensitive Chemiresistive HS Detection at Subzero Temperature over the Sb-Doped SnO@g-CN Heterojunctions under UV Illumination.

NASA has detected HS in the persistently shadowed region of the lunar South Pole through NIR and UV/vis spectroscopy remotely, but in situ detection is generally considered to be more accurate and convincing. However, subzero temperatures in space drastically reduce chemisorbed oxygen ions for gas sensing reactions, making gas sensing at subzero temperature something that has rarely been attempted. Herein, we report an in situ semiconductor HS gas sensor assisted by UV illumination at subzero temperature.

Target tumor therapy in human gastric cancer cells through the combination of docetaxel-loaded cationic lipid microbubbles and ultrasound-triggered microbubble destruction.

It is well accepted that ultrasound-induced microbubble (USMB) cavitation is a promising method for drug delivery. Ultrasound-targeted destruction of cytotoxic drug-loaded lipid microbubbles (LMs) is used to promote the treatment of cancer. This study aimed to investigate the antitumor effects from a combination of docetaxel-loaded cationic lipid microbubbles (DLLM) and ultrasound (US)-triggered microbubble destruction (UTMD) on gastric cancer (GC).

High-Performance Ppb Level NO Gas Sensor Based on Colloidal SnO Quantum Wires/TiCT MXene Composite.

Nitrogen dioxide is one origin of air pollution from fossil fuels with the potential to cause great harm to human health in low concentrations. Therefore, low-cost, low-power-consumption sensors for low-concentration NO detection are essential. Herein, heterojunction by SnO quantum wires, a traditional metal oxide NO sensing material, and TiCT MXene, a novel type of 2D layered material, was synthesized using a simple solvothermal method for enhancing gas-sensing performance and reducing operating temperature.

Highly Sensitive Love Mode Acoustic Wave Platform with SiO Wave-Guiding Layer and Gold Nanoparticles for Detection of Carcinoembryonic Antigens.

A highly sensitive and precise Love wave mode surface acoustic wave (SAW) immunosensor based on an ST-cut 90°X quartz substrate and an SiO wave-guiding layer was developed to detect cancer-related biomarkers of carcinoembryonic antigens (CEAs). A delay line structure of the SAW device with a resonant frequency of 196 MHz was designed/fabricated, and its surface was functionalized through CEA antibody immobilization. The CEA antibodies were bound with gold nanoparticles and CEA antibodies to form a sandwich structure, which significantly amplified the mass loading effect and enhanced the maximum responses by 30 times.

Activating transcription factor 3 protects alveolar epithelial type II cells from Mycobacterium tuberculosis infection-induced inflammation.

Activating transcription factor 3 (ATF3) is a stress-inducible gene reported with anti-inflammatory response effects against bacterial infections. This study focuses on the function of ATF3 in alveolar epithelial type II cells (A549) following Mycobacterium tuberculosis (MTB) infection. First, RT-qPCR results detected reduced ATF3 expression in broncho-alveolar lavage fluid (BALF) of MTB-infected patients, whereas the ATF3 level was upregulated in A549 cells at early stages after MTB infection but decreased later.

Interferon Regulatory Factor 4 (IRF4) Promotes Lipopolysaccharide-Induced Colonic Mucosal Epithelial Cell Proliferation by Regulating Macrophage Polarization.

Introduction: Ulcerative colitis (UC) is a chronic disease characterized by diffuse inflammation of the mucosa of colon and rectum. Interferon regulatory factor 4 (IRF4) mediates macrophage anti-inflammatory phenotype (alternatively activated macrophages [M2]). This study aimed to investigate the mechanism of IRF4 in lipopolysaccharide (LPS)-induced colonic mucosal epithelial cell proliferation via the regulation of macrophage polarization.

Extracting Lamb wave vibrating modes with convolutional neural network.

In recent years, micro-acoustic devices, such as surface acoustic wave (SAW) devices, and bulk acoustic wave (BAW) devices have been widely used in the areas of Internet of Things and mobile communication. With the increasing demand of information transmission speed, working frequencies of micro-acoustic devices are becoming much higher. To meet the emerging demand, Lamb wave devices with characteristics that are fit for high working frequency come into being.

Sponge-like loose and porous SnO microspheres with rich oxygen vacancies and their enhanced room-temperature gas-sensing performance.

Structure and surface modification of semiconductor materials are of great importance in gas sensors. In this study, a facile citric acid-assisted solvothermal method a precise calcination process was leveraged to synthesize sponge-like loose and porous SnO microspheres with rich oxygen vacancies (denoted as LP-SnO-O). When this material was used in a gas sensor, it exhibited an extremely high response to 10 ppm hydrogen sulfide gas at room temperature (/ = 9688), which was 54 times higher than that of commercial SnO.

An Algorithm for Solving the Phase Ambiguity Problem of SAW Delay-Line Sensor Systems.

Solving the phase ambiguity problem is crucial to achieving a wide-range and high-precision measurement for the frequency-domain sampling (FDS)-based surface acoustic wave (SAW) delay-line sensor systems. This study proposes an improved phase estimation algorithm called dual-band phase estimation (DBPE) to solve the problem. By using DBPE, the SAW sensor system can obtain an extensive and alterable measuring range without further requirements for sensor design or transmitted signals.

Development of Lamb Wave-Based Unidirectional Transducers Toward Highly Efficient Microfluidic Applications.

Acoustic wave devices have great potential for integration with lab-on-chip highly efficient microfluidics. This article investigates Lamb wave-based unidirectional transducers for application in acoustic wave-driven microfluidic devices with high efficiency. The simulation of the unidirectional transducer is performed via the finite element analysis.

Multiscale and hierarchical wrinkle enhanced graphene/Ecoflex sensors integrated with human-machine interfaces and cloud-platform.

Current state-of-the-art stretchable/flexible sensors have received stringent demands on sensitivity, flexibility, linearity, and wide-range measurement capability. Herein, we report a methodology of strain sensors based on graphene/Ecoflex composites by modulating multiscale/hierarchical wrinkles on flexible substrates. The sensor shows an ultra-high sensitivity with a gauge factor of 1078.

Research in Nonlinearity of Surface Acoustic Wave Devices.

Surface acoustic wave (SAW) devices are one of the indispensable components in the radio frequency (RF) front-end of mobile phones. With the development of mobile communication technology, the requirements for linear specification of devices are more and more strict. Nonlinear distortions of SAW devices have a serious influence on the application of mobile RF modules.

High-fidelity acoustic signal enhancement for phase-OTDR using supervised learning.

Phase-measuring phase-sensitive optical time-domain reflectometry (OTDR) has been widely used for the distributed acoustic sensing. However, the demodulated phase signals are generally noisy due to the laser frequency drift, laser phase noise, and interference fading. These issues are usually addressed individually.

Numerical Analysis of Viscous Dissipation in Microchannel Sensor Based on Phononic Crystal.

Phononic crystals with phononic band gaps varying in different parameters represent a promising structure for sensing. Equipping microchannel sensors with phononic crystals has also become a great area of interest in research. For building a microchannels system compatible with conventional micro-electro-mechanical system (MEMS) technology, SU-8 is an optimal choice, because it has been used in both fields for a long time.

High Performance Acoustic Wave Nitrogen Dioxide Sensor with Ultraviolet Activated 3D Porous Architecture of Ag-Decorated Reduced Graphene Oxide and Polypyrrole Aerogel.

Surface acoustic wave (SAW) devices have been widely explored for real-time monitoring of toxic and irritant chemical gases such as nitrogen oxide (NO), but they often have issues such as a complicated process of the sensing layer, low sensitivity, long response time, irreversibility, and/or requirement of high temperatures to enhance sensitivity. Herein, we report a sensing material design for room-temperature NO detection based on a 3D porous architecture of Ag-decorated reduced graphene oxide-polypyrrole hybrid aerogels (rGO-PPy/Ag) and apply UV activation as an effective strategy to further enhance the NO sensing performance. The rGO-PPy/Ag-based SAW sensor with the UV activation exhibits high sensitivity (127.

Comparison of Survival and Patterns of Recurrence in Gastric Neuroendocrine Carcinoma, Mixed Adenoneuroendocrine Carcinoma, and Adenocarcinoma.

Importance: Gastric neuroendocrine carcinoma and mixed adenoneuroendocrine carcinoma are rare pathological types of gastric cancer, and there is a lack of multicenter studies comparing the prognosis and recurrence patterns of gastric neuroendocrine carcinoma, gastric mixed adenoneuroendocrine carcinoma, and gastric adenocarcinoma.

Objective: To compare the differences in long-term survival and patterns of recurrence among gastric neuroendocrine carcinoma, gastric mixed adenoneuroendocrine carcinoma, and gastric adenocarcinoma.

Design, Setting, And Participants: This cohort study included patients with resectable gastric neuroendocrine carcinoma and gastric mixed adenoneuroendocrine carcinoma at 23 hospitals in China from January 2006 to December 2016.

Overexpression of microRNA-340-5p Ameliorates Inflammatory Response and Intracellular Survival of in Alveolar Type II Cells.

Background: The importance of microRNAs (miRs) has been documented in infections. This study estimated the role of miR-340-5p in (Mtb)-infected alveolar type II cells.

Methods: The microarray of GEO database was analyzed to find the differentially expressed miRs caused by Mtb infection, and miR-340-5p was selected as the research object.

IRF4 overexpression promotes the transdifferentiation of tregs into macrophage-like cells to inhibit the development of colon cancer.

Background: Interferon regulatory factor 4 (IRF4) is a transcription factor from the IRF factor family that exerts regulatory functions in the immune system and oncogenesis. However, the biological role of IRF4 in colon cancer is still unclear. The aim of this study is to investigate whether IRF4 participates in the immune response in colon cancer.

A 433-MHz surface acoustic wave sensor with Ni-TiO-poly(L-lysine) composite film for dopamine determination.

A ternary hybrid material composed of Ni nanoparticles (NPs), TiO NPs, and poly(L-lysine) (Ply) was used as a sensing material. It was electrodeposited in situ onto a commercial 433-MHz surface acoustic wave (SAW) resonator to construct a Ni-TiO-Ply/SAW sensor. The Ni-TiO-Ply sensing layer fully covered the resonant cavity of the SAW resonator.

Multi-institutional development and validation of a nomogram to predict recurrence after curative resection of gastric neuroendocrine/mixed adenoneuroendocrine carcinoma.

Objective: To establish a novel nomogram to predict individual 1, 3, and 5 years disease-free survival (DFS) of patients with gastric neuroendocrine carcinoma/mixed adenoneuroendocrine carcinoma [(MA)NEC].

Background: Among patients undergoing radical resection of gastric (MA)NEC, there is still a high tendency for relapse.

Methods: A retrospective analysis of 777 patients with gastric (MA)NEC at 23 centers in China from 2004 to 2015 was performed.