Risk Assessment of Cyclaniliprole Resistance in Peach-Potato Aphid Myzus persicae: Laboratory Selection, Inheritance, and Cross-Resistance Patterns.

Cyclaniliprole, a type of the third-generation anthranilic diamide insecticide, was mainly used for management of various pests. Myzus persicae (Hemiptera: Aphididae), known as the peach-potato aphid, is an economically essential pest with worldwide distribution. However, the risk assessment of cyclaniliprole in M.

Multiple gene-deletion vaccinia virus Tiantan strain against mpox.

Monkeypox virus (MPXV) is an important zoonotic pathogenic virus, which poses serious threats to public health. MPXV infection can be prevented by immunization against the variola virus. Because of the safety risks and side effects of vaccination with live vaccinia virus (VACV) strain Tian Tan (VTT), we constructed two gene-deleted VTT recombinants (TTVAC7 and TTVC5).

The MC-LR induced neuroinflammation and the disorders of neurotransmitter system in zebrafish (Danio rerio): Oxidative stress as a key.

Microcystin-leucine-arginine (MC-LR) has been shown to induce neuroinflammation and disrupt neurotransmitter system. However, little is known about the mechanism of toxicity. In this study, male adult zebrafish (Danio rerio) were exposed to MC-LR at concentrations of 0, 0.

Multifocality increases the risk of central compartment lymph node metastasis but is not related to the risk of recurrence and death in papillary thyroid carcinoma.

Background: Multifocality is a distinctive feature of papillary thyroid carcinoma (PTC); however, the biological behavior of PTC and its optimal management strategy remain unclear. The aim of this study was to analyze the clinical features and prognostic differences of multifocal papillary carcinoma and to guide the precise treatment of multifocal papillary carcinoma.

Methods: The medical records of 1,139 patients with PTC who had undergone total or hemi-thyroidectomy between April and October 2013 at the Tianjin Medical University Cancer Institute and Hospital were reviewed.

Influence of microbial agents-loaded biochar on bacterial community assembly and heavy metals morphology in sewage sludge compost: Insights from community stability and complexity.

Enhancing the passivation of heavy metals and increasing organic matter content during the composting of sewage sludge poses significant challenges for maximizing its utilization value. Results indicated that in the control, biochar, microbial agents and microbial agents-loaded biochar (BCLMA) groups, BCLMA addition led to a higher composting temperature, with increases of 17-62% in humic acid, 25-73% in germination index, and 30-35% in organic matter consumption. And the residual fraction of Cu, Zn, Cr and Cd were increased by 30%, 12%, 22% and 17%, respectively.

Chemical cross-linking facilitates antigen uptake and presentation and provides improved protection from Mpox with a dual-antigen subunit vaccine.

Antigen uptake, processing, and presentation are crucial for the immune responses of protein-based vaccines. Herein, we introduced a reversible chemical cross-linking strategy to engineer protein antigens, which can be tracelessly removed upon antigen-presenting cell (APC) uptake and cellular reduction. The chemically cross-linked antigen proteins presented significantly enhanced uptake and epitope presentation by APC.

Identification of quantitative trait loci and candidate genes associated with growth curve parameters in chinese wenshang barred chickens.

The growth curve is a vital instrument for assessing and forecasting weight and developmental shifts in livestock and poultry, which reflects the changes of bodyweight traits with time and plays a key role in guiding breeding and production approaches. This study performed a genome-wide association study (GWAS) for growth curve parameters generated by nonlinear models which fit original weight-age records, to discover the SNPs and candidate genes correlated with growth traits. Data from 362 Chinese Wenshang Barred Chickens weighed at the age of 0, 2, 4, 6, 8, 10, 12, 14, 16, and 18 weeks were used to fit the Gompertz, Logistic, and von Bertalanffy growth models.

Sesamin Alleviates Allergen-Induced Diarrhea by Restoring Gut Microbiota Composition and Intestinal Barrier Function.

Food allergens are the key triggers of allergic diarrhea, causing damage to the immune-rich ileum. This weakens the mucosal barrier and tight junctions, increases intestinal permeability, and exacerbates allergen exposure, thereby worsening the condition. Sesamin, a natural lignan isolated from sesame seed, has shown potential in regulating immune responses, but its effects on intestinal health remain unclear.

Comparative Transcriptome Analysis Reveals Mechanisms of Differential Salinity Tolerance Between and .

Background: and have obvious morphological features and strongly tolerate saline-alkali environments. However, the mechanisms that lead to the differences in saline-alkali tolerance between them remain unclear.

Methods: In this study, we employed comparative transcriptome analysis to investigate and under saline-alkali stress.

Comparative Analysis of Intestinal Microbiota in Wild, Domesticated, and Cultured .

The impact of the living environments on the intestinal microbiota of was studied by analyzing intestinal microbiota diversity, composition, and potential function among wild, domesticated, and cultured groups. The results showed that the fish living in the wild environment exhibited the highest alpha diversity of intestinal microbiota. Intestinal microbial communities in the three groups clustered by living environment, with domesticated and cultured groups showing higher similarity.

Vertical directional coupling based grating emission engineering for optical phased arrays: publisher's note.

This publisher's note contains a correction to Opt. Lett.49, 3102 (2024)10.

Microcystin-LR induces fatty liver metabolic disease in zebrafish through the PPARα-NOD1 pathway: In vivo, in vitro, and in silico investigations.

Hepatic lipid metabolism dysfunction caused by cyanobacteria bloom-released microcystin-LR (MC-LR) contributes to the development of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis (NASH), thereby severely impacting the health and safety of animals and humans. In this study, the effects and mechanisms of different environmental concentrations of MC-LR (0, 0.1, 1, and 10 μg/L) on fatty liver metabolic disease in zebrafish were investigated using in vivo, in vitro, and in silico models.

Robust, Antifouling, and Hydrophilic Particle-Based Double-Network Hydrogel-PVDF Interpenetrating Microfiltration Membrane.

Poly(vinylidene fluoride) (PVDF) membranes with highly hydrophilic and antifouling properties are desirable for oily wastewater treatment. Herein, we report (1) a strategy of bulk modification of PVDF by integration of PVDF and a particle-based double-network (PDN) hydrogel, poly-2-acrylamido-2-methylpropanesulfonate/polyacrylamide (PAMPS/PAAm), via a strong PDN and PVDF interpenetrating polymer network (PDN-PVDF IPN) to obtain a PVDF/PDN solution and (2) the subsequent casting of it into a microfiltration membrane via spray-assisted non-solvent-induced phase separation (SANIPS). The IPN structure modulates the surface segregation behavior of the highly hydrophilic and robust PDN hydrogel in the process of SANIPS, endowing the resulting PVDF/PDN membrane with excellent bulk mechanical properties and much enhanced wettability and thereby high oil/water emulsion separation efficiency and antifouling performance.

Characterization of dipyridamole as a novel ferroptosis inhibitor and its therapeutic potential in acute respiratory distress syndrome management.

: Ferroptosis in lung epithelium and endothelium contributes to the pathogenesis of acute respiratory distress syndrome (ARDS), a critical and often fatal condition marked by acute inflammation and elevated pulmonary vascular permeability. Despite this, there are currently no FDA-approved therapeutics specifically targeting ferroptosis for ARDS management. : A screening of 259 FDA-approved drugs was conducted to identify an effective ferroptosis inhibitor in pulmonary epithelial and endothelial cells.

Glycogen-accumulating organisms promote phosphate recovery from wastewater by pilot-scale biofilm sequencing batch reactor: Performance and mechanism.

A high phosphate (P) recovery concentration was achieved in pilot-scale biofilm sequencing batch reactor (BSBR) with a low carbon source (C) cost. Especially, a high-abundance glycogen-accumulating organisms (GAOs) (13.93-31.

Case report: A follow-up report of omental packing and drug therapy for canine prostate adenocarcinoma.

Canine prostate is susceptible to diseases such as cysts, abscesses, and tumors. A 15-year-old male castrated Chinese rural dog underwent staged treatment. Preliminary diagnosis is based on examination results, including clinical symptoms (tenesmus, dysuria, frequent urination, and hematuria); hematology (elevated neutrophil count); X-rays (swelling of the prostate); ultrasound examination (less uniform echo in the prostate region, no echo effect in parenchyma); biopsy smear of prostate tissue (large number of neutrophils and rod-shaped bacteria).

Integrative analysis of non12-hydroxylated bile acid revealed the suppressed molecular map of alternative pathway in nonalcoholic steatohepatitis mice.

Bile acids (BAs) are significantly altered in the liver and serum of patients with nonalcoholic steatohepatitis (NASH). However, the underlying mechanisms of these changes, particularly BA alternative pathways (BAP) responsible for non12-OH BAs, remain unclear. RNA-seq data were initially analyzed to reveal the changes of gene expression in NASH patients.

Long-term effects of dead algal deposition on sediment surfaces: Behavior of endogenous phosphorus release in sediments.

Algae blooms are frequently triggered owing to the improvements in aquatic trophic levels. The aggregated algae from these blooms are eventually dead and accumulate on sediment surfaces, impacting the microenvironment and phosphorus cycling in aquatic systems. However, research on the effects of naturally dead algal deposition on endogenous P release from sediments is lacking.

An Artificial Intelligence-Driven Preoperative Radiomic Subtype for Predicting the Prognosis and Treatment Response of Patients with Papillary Thyroid Carcinoma.

Purpose: From 8% to 28% of patients with papillary thyroid carcinoma (PTC) experience recurrence, complicating risk stratification and treatment. We previously identified an inflammatory molecular subtype of PTC associated with poor prognosis. Based on this subtype, we aimed to develop and validate a noninvasive radiomic signature to predict prognosis and treatment response in patients with PTC.