Creep Properties and Corrosion Behavior of TP347H Stainless Steel with Al in Molten Carbonate Salt.

Molten carbonate salts are a promising candidate for next-generation concentrated solar power technology owing to their excellent heat storage and heat transfer properties. This represents overcoming several problems that structural materials exhibit, including severe corrosion and high-temperature creep. Alloys with an aluminum element are alternatives in this regard as they are highly resistant to corrosive environments.

Assessing U.S. public perceptions of global warming using social survey and climate data.

This paper presents a methodological approach for assessing the relationship between weather patterns, regional climate trends, and public perceptions of global warming in the United States with control of socioeconomic, political, and ideological variables. We combined social survey data from the Gallup Poll Social Series (GPSS) with environmental data from the National Oceanic and Atmospheric Administration (NOAA) and the PRISM Climate Group. Logistic regression models were employed, enhanced by Eigenvector Spatial Filtering (ESF) to address spatial autocorrelation.

[The Prognostic Predictive Value of mutation Variant Allele Frequency in Diffuse Large B-Cell Lymphoma].

Objective: To explore the effect of mutation variant allele frequency(VAF) on the prognosis of diffuse large B-cell lymphoma(DLBCL) patients.

Methods: This study included 155 patients with DLBCL who were first diagnosed in the People's Hospital of Xinjiang Uygur Autonomous Region from March 2009 to March 2022. Complete clinical data and paraffin-embedded tumor tissue samples were obtained, and DNA was extracted from tumor tissues.

An atlas of the shared genetic architecture between atopic and gastrointestinal diseases.

Comorbidity among atopic diseases (ADs) and gastrointestinal diseases (GIDs) has been repeatedly demonstrated by epidemiological studies, whereas the shared genetic liability remains largely unknown. Here we establish an atlas of the shared genetic architecture between 10 ADs or related traits and 11 GIDs, comprehensively investigating the comorbidity-associated genomic regions, cell types, genes and genetically predicted causality. Although distinct genetic correlations between AD-GID are observed, including 14 genome-wide and 28 regional correlations, genetic factors of Crohn's disease (CD), ulcerative colitis (UC), celiac disease and asthma subtypes are converged on CD4 T cells consistently across relevant tissues.

Occurrence, bioaccumulation and trophodynamics of per- and polyfluoroalkyl substances (PFAS) in terrestrial and marine ecosystems of Svalbard, Arctic.

Per- and polyfluoroalkyl substances (PFAS) enter the Arctic through long-range transport and local pollution. To date, little is known about their behavior in plant and benthic marine food webs in remote Arctic. In this study, we analyzed the environmental distribution and nutrient transfer of 20 PFAS in soil, sediment, plant and benthic biota samples collected between 2014 and 2016 in Svalbard, Arctic.

Novel insights into non-coding RNAs and their role in hydrocephalus.

A large body of evidence has highlighted the role of non-coding RNAs in neurodevelopment and neuroinflammation. This evidence has led to increasing speculation that non-coding RNAs may be involved in the pathophysiological mechanisms underlying hydrocephalus, one of the most common neurological conditions worldwide. In this review, we first outline the basic concepts and incidence of hydrocephalus along with the limitations of existing treatments for this condition.

Circulating tumor cells are associated with lung cancer subtypes: a large-scale retrospective study.

Background: Circulating tumor cells (CTCs) provide a unique resource to decipher cell molecular properties of lung cancer. However, the clinicopathologic and radiological features associated with CTCs in different lung cancer subtypes remain poorly characterized. The aim of this study was to explore the clinicopathological and radiological features of CTCs in different lung cancer subtypes.

Carboplatin combined with arsenic trioxide versus carboplatin combined with docetaxel treatment for LACC: A randomized, open-label, phase II clinical study.

Purpose: This study compared the efficacy and safety of carboplatin combined with arsenic trioxide versus carboplatin combined with docetaxel in treating locally advanced cervical cancer (LACC).

Methods: A total of 48 patients were enrolled between January 2019 and December 2022 and randomly assigned to the experimental group (carboplatin + arsenic trioxide, = 24) or control group (carboplatin + docetaxel, = 24). The clinical efficacy, adverse reactions, and serological markers were analyzed.

Regenerative Potential Nanomedicine of Adipocyte Stem Cell-Derived Exosomes in Senescent Skin Tissue.

Introduction: Skin is the first-line barrier defense against infection, irradiation, and toxins, but is prone to natural aging (intrinsic aging) and environmental factors (extrinsic aging). Hence, there is an increasing urgency to explore an effective treatment for aging skin. This study was focused on testing the potential of utilizing adipocyte stem cell derived exosomal as nanomedicine to regenerate the dermal layer and counteract signs of skin aging.

Histone Methylation, Energy Metabolism, and Alzheimer's Disease.

Alzheimer's disease (AD) is an insidious, progressive, and irreversible neurodegenerative disease characterized by the deposition of extracellular amyloid β-protein (Aβ) to form senile plaques and abnormal phosphorylation of intracellular tau protein to form neuronal fiber tangles. The pathogenesis of AD is complex, and there are several hypotheses, primarily including the Aβ cascade hypothesis, the neurofibrillary tangle hypothesis, the inflammatory hypothesis, and the cholinergic hypothesis. It has been suggested that the dysregulation of multiple energy metabolic pathways, especially mitochondria metabolism, may be related to the severity of AD pathology and disease symptoms in the brain.

Optimizing geographical traceability models of Chinese Lycium barbarum: Investigating effects of region, cultivar, and harvest year on nutrients, bioactives, elements and stable isotope composition.

Lycium barbarum is a type of "medicine-food homology" whose geographical origin has attracted strong interest from consumers due to different regional quality characteristics. A sophisticated OPLS-DA model to verify Lycium barbarum origin was developed using 266 samples gathered from five cultivars in two regions between 2020 and 2022, which was based on 67 indices, including nutrients, bioactives, elements and stable isotopes. Twelve variables (fructose, δH, glucose, tartaric acid, Mo, Na, Sr, His, Phe, Mn, Lys and Rb) were selected to refine models that could distinguish Lycium barbarum origin without being impacted by cultivar or year.

Development and Validation of a Screening Tool for Generalized Anxiety and Major Depressive Disorder in Patients with Chronic Obstructive Pulmonary Disease.

Purpose: Anxiety and depression are often underdiagnosed in patients with chronic obstructive pulmonary disease (COPD). This study aimed to develop and validate a screening tool for anxiety and depression in COPD patients.

Methods: Stable COPD patients were consecutively recruited from November 2021 to October 2023 and underwent a psychiatric interview to diagnose generalized anxiety disorder (GAD) and/or major depressive disorder (MDD) based on the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition.

Corrigendum: Myricetin suppresses TGF-β-induced epithelial-to-mesenchymal transition in ovarian cancer.

[This corrects the article DOI: 10.3389/fphar.2023.

Deciphering Water Oxidation Catalysts: The Dominant Role of Surface Chemistry over Reconstruction Degree in Activity Promotion.

Water splitting hinges crucially on the availability of electrocatalysts for the oxygen evolution reaction. The surface reconstruction has been widely observed in perovskite catalysts, and the reconstruction degree has been often correlated with the activity enhancement. Here, a systematic study on the roles of Fe substitution in activation of perovskite LaNiO is reported.

Role of immune dysregulation in peri-implantitis.

Peri-implantitis, a complex condition that can lead to dental implant failure, is characterized by inflammatory destruction resulting from immune dysregulation. Oral microbial dysbiosis and foreign body stimulation are the main factors contributing to such dysregulation, impairing immune cell function and triggering an inflammatory response. Immune dysregulation plays a critical role in the pathophysiology of peri-implantitis, impacting the balance of T cell subsets, the production of inflammatory factors, and immune-related molecular signaling pathways.

Volume of detonation determination based on gaseous products of energetic materials by time resolved LIPS combined with schlieren image.

The safe and fast measurement of volume of detonation (VoD) is always a hard task for macroscale explosion even though it is one of the important parameters to evaluate the explosion performance. Therefore, a promising technology to determine the VoD is highly desirable for evaluation of energetic materials. Herein, a new method of VoD determination based on gaseous products via small dose energetic materials by time correlated laser induced plasma spectroscopy (LIPS) combined with schlieren image was proposed.

Hermetic hydrovoltaic cell sustained by internal water circulation.

Numerous efforts have been devoted to harvesting sustainable energy from environment. Among the promising renewable resources, ambient heat exhibits attractive prospects due to its ubiquity and inexhaustibility, and has been converted into electricity through water evaporation-induced hydrovoltaic approaches. However, current hydrovoltaic approaches function only in low-humidity environments and continuously consume water.

Authenticating the Geographical Origin of Jingbai Pear in Northern China by Multiple Stable Isotope and Elemental Analysis.

The Jingbai pear is one of the best pear species in China with high quality and nutrition values which are closely linked to its geographical origin. With the purpose of discriminating the PGI Mentougou Jingbai pear from three other producing regions, the stable isotope ratios and elemental profiles of the pears ( = 52) and the corresponding soils and groundwater were determined using isotope ratio mass spectrometry (IRMS) and inductively coupled plasma mass spectrometry (ICP-MS), respectively. The results revealed that δN, δO, and Li were significantly different ( < 0.

Taxifolin ameliorates the D-galactose-induced aging of mouse hippocampal neurons HT-22 cells through modulating SIRT1/p53 and PI3K/AKT signaling pathways.

By establishing an model of D-Gal-induced brain neuronal cell (HT-22) senescence, it was found that TAX treatment significantly increased the activities of SOD and GSH, while decreasing MDA levels in aging HT-22 cells, indicating that TAX effectively restored the total antioxidant capacity and antioxidant enzyme activity of aging HT-22 cells induced by D-Gal, and attenuated cellular oxidative stress injury. In addition, taxifolin could also protect HT-22 cells from aging by up-regulating SIRT1 while reducing the expression of Ac-p53, indicating that TAX may be an active substance that can effectively delay cell aging.