Publications by authors named "Leyton A"

Article Synopsis
  • Marine thraustochytrids, like Thraustochytrium sp. RT2316-16, are important for producing beneficial lipids, particularly omega-3 fatty acids, and their growth relies on amino acids in the culture medium.
  • This study examines how individual amino acids affect biomass and lipid production, utilizing a metabolic network model to link nutrient consumption to growth rates.
  • Findings show a correlation between ATP production for cell maintenance and glucose consumption, which was used in optimization to accurately predict growth rates under various conditions.
View Article and Find Full Text PDF

Intimate partner violence (IPV) is a major public health issue in Honduras and other low- and middle-income countries, with few victims seeking help. While structural factors, such as lack of services and economic barriers, are often cited as reasons for not seeking help, social and cultural factors may also play a role. This study aims to describe the normative social environment that may hinder women's help-seeking behaviors for IPV.

View Article and Find Full Text PDF

The psychrophilic marine microorganism sp. RT2316-16 can produce carotenoids as well as lipids containing the omega-3 polyunsaturated fatty acids (PUFA) eicosapentaenoic acid and docosahexaenoic acid. This work reports on the effects of the composition of the culture medium, including certain amino acids, on growth and lipid synthesis by RT2316-16.

View Article and Find Full Text PDF

The carotenogenic thraustochytrid sp. RT2316-16 was grown in batch and repeated-batch cultures using different feeds containing glucose, or glycerol, and yeast extract, for the production of lipids, phospholipids and carotenoids. RT2316-16 produced canthaxanthin, astaxanthin and β-carotene.

View Article and Find Full Text PDF

Eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and carotenoids are needed as human dietary supplements and are essential components in commercial feeds for the production of aquacultured seafood. Microorganisms such as thraustochytrids are potential natural sources of these compounds. This research reports on the lipid and carotenoid production capacity of thraustochytrids that were isolated from coastal waters of Antarctica.

View Article and Find Full Text PDF

Seaweed processing generates liquid fraction residual that could be used as a low-cost nutrient source for microbial production of metabolites. The strain is able to produce antimicrobial compounds known as sophorolipids. Our aim was to evaluate sophorolipid production, with antibacterial activity, by marine using liquid fraction residual (LFR) from the brown seaweed as the nutrient source.

View Article and Find Full Text PDF

This study examined the effectiveness of anti-smoking messages in positively shifting perceptions of risks related to smoking among adolescents in urban Ghana, both directly through exposure to messaging and indirectly through catalyzing discussions among peers and adults. We used data from two waves of a population-based survey of 3775 adolescent girls and 3279 adolescent boys aged 13-16 years in the urban areas of Accra, Teshie, Kumasi and Sunyani in Ghana. Using an interviewer-directed questionnaire, information was collected on sociodemographic characteristics, tobacco knowledge, exposure to messages about tobacco, frequency of conversations with peers and adults about the health risks associated with smoking, as well as beliefs and attitudes towards smoking.

View Article and Find Full Text PDF

RT2316-13 synthesizes lipids rich in eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). The content of these fatty acids in the total lipids depended on growth temperature. Sequencing technology was used in this work to examine the thraustochytrid's response to a decrease in growth temperature from 15 °C to 5 °C.

View Article and Find Full Text PDF

Background: Given the long-term health effects of smoking during adolescence and the substantial role that tobacco-related morbidity and mortality play in the global burden of disease, there is a worldwide need to design and implement effective youth-focused smoking prevention interventions. While smoking prevention interventions that focus on both social competence and social influence have been successful in preventing smoking uptake among adolescents in developed countries, their effectiveness in developing countries has not yet been clearly demonstrated. SKY Girls is a multimedia, empowerment and anti-smoking program aimed at 13-16-year old girls in Accra, Ghana.

View Article and Find Full Text PDF

Background: Women are under-represented in many mid-career infectious diseases research fellowships, including a TDR fellowship for low- and middle-income country (LMIC) researchers. TDR solicited creative ideas as part of a challenge contest to increase the number of women fellowship applicants. The purpose of this study is to examine themes from submitted ideas and the impact of implementing the top three ideas on the number of women applicants.

View Article and Find Full Text PDF

Background: Intimate Partner Violence (IPV) against women is a complex phenomenon with long-term consequences for victims and their families.

Objective: The goals of this study are two-fold: to identify common patterns of co-occurring and/or successive experiences with IPV; and to study the association between these IPV patterns and outcomes of Early Childhood Development (ECD) among the victim's children.

Data And Participants: Data was obtained from the 2011-12 Honduras Demographic Health Survey (DHS).

View Article and Find Full Text PDF

Production of biomass and lipids in batch cultures of the Antarctic thraustochytrid Oblongichytrium sp. RT2316-13, is reported. The microorganism proved capable of producing nearly 67% docosahexaenoic acid (DHA) and 15% eicosapentaenoic acid (EPA) in its total lipid fraction.

View Article and Find Full Text PDF

The experience of intimate partner violence (IPV) is influenced by individual, relationship, community, and societal-level factors, including the prevalence and acceptance of societal violence in which the victim lives. These factors transcend a woman's present circumstances and personal history and the gender and power relationships within her household. This is particularly relevant in Honduras, where a high level of IPV occurs within a traditionally patriarchal society and growing societal violence and crime.

View Article and Find Full Text PDF

Thraustochytrids have been isolated from different aquatic systems; however, few studies have reported their occurrence in Antarctica. In this study, 13 strains close to strains belonging to the genera Oblongichytrium, Thraustochytrium, and Aurantiochytrium were isolated from seawater samples collected near the Antarctic Base Professor Julio Escudero (S 62°12'57' E 58°57'35″). Docosahexaenoic acid (DHA) was found in the total lipids of all the isolates; DHA content of the biomass (dry weight) varied between 3.

View Article and Find Full Text PDF

In 2004, a global spread of Chikungunya fever affected most tropical and subtropical regions of the world. In 2016, an outbreak occurred in Northeast Brazil with hundreds of cases documented. Solid organ transplant recipients have a modified immune response to infection and the clinical course is usually different from immunocompetent patients.

View Article and Find Full Text PDF

Aims: To evaluate an aqueous extract of Macrocystis pyrifera as a nutrient source for the production of carotenoids by a marine Rhodotorula mucilaginosa isolated from seaweed samples.

Materials And Results: The effect of different culture conditions on the concentration of biomass and total pigments was evaluated using a Box-Behnken experimental design. The seaweed extract contained 15% w w of protein and 20% w w of carbohydrate; the main sugar in this fraction was trehalose (78%).

View Article and Find Full Text PDF

Total lipids and docosahexaenoic acid (DHA) production by a Chilean isolated thraustochytrid were evaluated under different growth conditions in shake flasks. The analyzed strain was identified as Thraustochytrium striatum according to an 18S rRNA gene sequence analysis. The strain (T.

View Article and Find Full Text PDF

Background: Population-based measures of intervention coverage are used in low- and middle-income countries for program planning, prioritization, and evaluation. There is increased interest in effective coverage, which integrates information about service quality or health outcomes. Approaches proposed for quality-adjusted effective coverage include linking data on need and service contact from population-based surveys with data on service quality from health facility surveys.

View Article and Find Full Text PDF

Phlorotannins are secondary metabolites produced by brown seaweed, which are known for their nutraceutical and pharmacological properties. The aim of this work was to determine the type of macroporous resin and the conditions of operation that improve the purification of phlorotannins extracted from brown seaweed, Macrocystis pyrifera. For the purification of phlorotannins, six resins (HP-20, SP-850, XAD-7, XAD-16N, XAD-4 and XAD-2) were assessed.

View Article and Find Full Text PDF

Objective: To examine the efficacy of topical chlorhexidine as an intervention on neonatal umbilical cord stumps and its association with neonatal mortality and omphalitis.

Study Design: Meta-analysis of randomized controlled trials (RCTs).

Method: PubMed, EMBASE, CINAHL, IMSEAR, Google Scholar, Cochrane Central Register of Controlled Trials, Cochrane Pregnancy and Childbirth Group's Trials Register and Clinicaltrials.

View Article and Find Full Text PDF

Colletotrichum species have been rarely implicated in human disease. We describe a case of deep soft tissue mycosis following a penetrating injury with a lemon tree thorn. Direct Blankophor BA (Bayer) stain from intraoperative tissue showed fungal elements.

View Article and Find Full Text PDF

Objective: The objective of this study was to assess the prevalence and characteristics of medication errors in pediatric and neonatal inpatients and to measure the impact of interventions to reduce medication errors.

Methods: A preintervention and postintervention cross-sectional study was conducted of a sample of prescriptions that were ordered by physicians and medications that were administered by nurses to patients at the NICU, PICU, and general pediatric settings at the Hospital Italiano de Buenos Aires Department of Pediatrics in 2002 and 2004. Number and type of errors, time shift on which they occurred, and whether they had any kind of adverse event on the patient were recorded.

View Article and Find Full Text PDF

Background: Tomato has a high antioxidant capacity due to its high content of vitamin C, vitamin E and lycopene that is a powerful free radical scavenger. However, the effects of tomato on plasma lipoproteins is not well known, and there is little evidence about the relationship between tomato consumption and oxidative state changes in humans.

Aim: To assess in vivo the effects of dietary supplementation with pure concentrated tomato juice on short term changes in oxidative state and plasma lipoproteins in healthy volunteers.

View Article and Find Full Text PDF