has emerged as a significant fungal threat due to its rapid worldwide spread since its first appearance, along with its potential for antimicrobial resistance and virulence properties. This study was designed to examine virulence characteristics, the efficacy of ceragenins, and biofilm-derived drug resistance in seven strains isolated from Turkish intensive care patients. It was observed that none of the tested strains exhibited proteinase or hemolysis activity; however, they demonstrated weak phospholipase and esterase activity.
View Article and Find Full Text PDFIntroduction: Rapid and accurate diagnosis is critically important in invasive and disseminated fungal infections for appropriate antifungal treatment.
Hypothesis: MALDI-TOF MS systems are effective for fast and accurate identification of Candida species.
Aim: We aimed to compare two MALDI-TOF MS systems for the rapid identification of non-albicans Candida and rare clinical yeast species.
Sisli Etfal Hastan Tip Bul
March 2021
Objectives: Hepatitis C virus (HCV), which has no protective vaccine, is a common cause of chronic hepatitis, which is a severe public health threat. There are differences in nucleotide and amino acid sequences in different regions of the HCV genome. As a result of these differences, HCV has been shown to have at least seven major genotypes and many subtypes.
View Article and Find Full Text PDFBackground: Although Methicillin resistant Staphylococcus aureus (MRSA) is one of the major pathogens of healthcare associated infections, we had only sporadic cases in our intensive care unit (ICU) for years.
Aims: To investigate the sudden increase in the number of MRSA cases in ICU.
Study Design: Descriptive study.