Publications by authors named "Leyla H Shigapova"
Article Synopsis
- Two new Arctic incirrate octopus species are identified, with one, Muusoctopus aegir, receiving formal description due to distinct characteristics like absence of stylets and unique funnel organ morphology.
- The study also explores morphology and reproductive biology of related species, contributing important data on gill lamellae counts and reproductive system structure.
- It includes tools for species identification and equations to estimate physical measurements of the new species, expanding knowledge on the diversity and distribution of Muusoctopus in Arctic waters.
Genome instability-the increased tendency of acquiring mutations in the genome and ability of a cell to tolerate high mutation burden-is one of the drivers of cancer. Genome instability results from many causes including defects in DNA repair systems. Previously, it has been shown that germline pathogenic mutations in DNA Mismatch Repair (MMR) pathway cause cancer-predisposing Lynch Syndrome.
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- The text discusses a specific strain of a gram-negative bacterium, NK-1, that can cause catheter-associated urinary tract infections (CAUTIs).
- It provides details about the strain's genome, which is 6,232,464 base pairs long and contains genes linked to virulence factors like drug resistance and adhesion.
- The study includes the strain's sequence type (ST 216) and mentions the project's data is available in a genetic database for further research.
Objectives: Staphylococcus species of the family Staphylococcaceae are facultatively anaerobic Gram-positive cocci growing in clusters, pairs and occasionally in short chains. Staphylococci can be detected in different environments. They are common commensals, but some can also cause infections in humans.
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- Bacillus species, particularly B. pumilus, are resilient Gram-positive bacteria that can withstand harsh environmental conditions and are valuable for biotechnological applications like waste treatment and food production.
- The study focuses on the genomics of a specific strain, EZ-C07, isolated from agricultural waste, which has a draft genome of 3.7 million base pairs and contains a significant number of coding sequences.
- The strain was confirmed to be B. pumilus through genetic analysis, and its genome is available for public access in several scientific databases.
Immune mechanisms recently emerged as important contributors to migraine pathology with cytokines affecting neuronal excitation. Therefore, elucidating the profile of cytokines activated in various forms of migraine, including those with a known genetic cause, can help in diagnostic and therapeutic approaches. Here we (i) performed exome sequencing to identify the causal gene mutation and (ii) measured, using Bio-Plex technology, 22 cytokines in serum of patients with familial migraine (two with hemiplegic migraine and two with migraine with aura) from a Russian family that ethnically belongs to the Tatar population.
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