Publications by authors named "Leyla Guven"

Astragalus species are traditionally used for diabetes, ulcers, leukemia, wounds, stomachaches, sore throats, abdominal pain, and toothaches. Although the preventive effects of Astragalus species against diseases are known, there is no record of the therapeutic effects of . In this study, we aimed to evaluate the in vitro antiglaucoma, antidiabetic, anti-Alzheimer's disease, and antioxidant activities of the methanolic (MEAA) and water (WEAA) extracts of the aerial part of .

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Propolis is a complex natural compound that honeybees obtain from plants and contributes to hive safety. It is rich in phenolic and flavonoid compounds, which contain antioxidant, antimicrobial, and anticancer properties. In this study, the chemical composition and antioxidant activities of propolis were investigated; ABTS, DPPH and DMPD were prepared using radical scavenging antioxidant methods.

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Article Synopsis
  • Magnofluorine, a plant-derived secondary metabolite, demonstrates significant antioxidant activity through various bioanalytical assays, outperforming some common synthetic antioxidants.
  • The compound exhibits inhibition effects on key metabolic enzymes associated with diseases like diabetes and Alzheimer's, suggesting potential therapeutic applications.
  • Molecular docking studies indicate Magnofluorine's interactions with these enzymes, highlighting its promise for future industrial and medicinal use.
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Wound is tissue damage that occurs in the skin. species (Altınotu) are rich in phenolic compounds used in traditional medicine for wound healing. The main component in their flower head (capitulum) is phenolic compounds.

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The aim of this study was to investigate the effects of Achillea millefolium extract in paclitaxel-induced testicular toxicity in rats. The groups were designed as (1) control, (2) paclitaxel (8 mg/kg, intraperitoneally), (3) paclitaxel (8 mg/kg, intraperitoneally) + Achillea millefolium (200 mg/kg, orally for 14 consecutive days) and (4) paclitaxel (8 mg/kg, intraperitoneally) + Achillea millefolium (400 mg/kg, orally for 14 consecutive days). Serum levels of testosterone, luteinising hormone and follicle-stimulating hormone, as well as total antioxidant capacity and total oxidant status were measured one day after receiving the last dose of Achillea millefolium extract.

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