Publications by authors named "Leyan Zhang"

With the innovation of modern electronics, heat dissipation in the devices faces several problems. In our work, boron nitride (BN) with good thermal conductivity (TC) was successfully fabricated by constructing the BN along the axial direction and the surface-grafted BN hybrid composite fibers via the wet-spinning and hot-pressing method. The unique inter-outer and inter-interconnected hybrid structure of composite fibers exhibited 176.

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Bisphenol A (BPA) is a typical food chemical contaminant with various detrimental effects, especially on reproductive system. Male prostate damage is also one of its major adverse health effects, of which mode of action (MOA) remains unclear. This study aims to explore the MOA for prostate toxicity of BPA using human normal prostate epithelial cell RWPE-1 for 28-day human-relevant-level exposure.

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Article Synopsis
  • Bisphenol A (BPA) is identified as an endocrine disruptor linked to cardiovascular toxicity, necessitating an exploration of its adverse outcome pathway (AOP).
  • The study utilized bioinformatics to analyze interactions between BPA, genetic factors, and cardiac effects, uncovering key target genes (like ESR2 and MAPK1) and related heart phenotypes.
  • The proposed AOP suggests that BPA activates specific signaling pathways, leading to calcium imbalance and inflammation, ultimately impairing cardiac function and increasing the risk of heart diseases, with a QWOE score indicating moderate confidence in the findings.
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  • - The study presents a novel fabric made from basalt fibers and cotton yarns designed for solar evaporation and power generation to tackle issues of water and electricity scarcity.
  • - The fabric allows efficient water transport and thermal management, achieving a high evaporation rate and impressive energy efficiency under sunlight, significantly outperforming traditional methods.
  • - When paired with a thermoelectric module, the system demonstrates substantial power output potential, suggesting that this integrated approach can lead to large-scale desalination and energy production in outdoor settings.
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  • Natural revegetation (VR) shows a greater increase in soil organic carbon (SOC) accumulation compared to cropping over 24 years, primarily due to a higher contribution of plant-derived carbon.
  • The study reveals that recalcitrant organic carbon plays a larger role in SOC variation than easily oxidizable carbon, while microbial necromass percentages are similar between the two land use types.
  • Key factors influencing SOC formation include microbial and plant-derived sources, with soil nitrogen being significant in both VR and cropland; however, phosphorus content is crucial in cropland, whereas climatic factors are more important in VR.
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The combined application of chemical and organic fertilizers has been recognized to enhance soil fertility and foster the soil microbial ecosystem. However, the optimal ratio of chemical and organic fertilizers in oilseed rape cultivation is still uncertain, and the role of rhizosphere effect is still unclear. Thus, this study aimed to elucidate the impacts of varying ratios of chemical and organic fertilizers on the structure and potential functionalities of rhizosphere and non-rhizosphere soil microbial communities.

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Water and fertilizer managements are the most common practices to maximize crop yields, and their long-term impact on soil microbial communities has been extensively studied. However, the initial response of microbes to fertilization and soil moisture changes remains unclear. In this study, the immediate effects of nitrogen (N)-fertilizer application and moisture levels on microbial community of paddy soils were investigated through controlled incubation experiments.

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Peste des petits ruminants virus (PPRV) is an important pathogen that seriously influences the productivity of small ruminants worldwide. PPRV is lymphotropic in nature and SLAM was identified as the primary receptor for PPRV and other Morbilliviruses. Many viruses have been demonstrated to engage extracellular vesicles (EVs) to facilitate their replication and pathogenesis.

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Purpose: To investigate the epidemiological features of infection of the hepatobiliary system of patients in Yantai, China.

Methods: This retrospective study was conducted from January to December 2019 in Yantai Yuhuangding Hospital. Patients for whom was isolated from the hepatobiliary system were considered for inclusion.

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Cefoperazone/sulbactam (CSL) and piperacillin/tazobactam (TZP) are commonly used in clinical practice in China because of their excellent antimicrobial activity. CSL and TZP-nonsusceptible are typically resistant to extended-spectrum cephalosporins such as ceftriaxone (CRO). However, 11 nonrepetitive strains, which were resistant to CSL and TZP yet susceptible to CRO, were collected from January to December 2020.

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Peste des petits ruminants virus (PPRV) is an important pathogen that seriously influences the productivity of small ruminants worldwide. We showed previously that PPRV induced sustained autophagy for their replication in host cells. Many studies have shown that exosomes released from virus-infected cells contain a variety of viral and host cellular factors that are able to modulate the recipient's cellular response and result in productive infection of the recipient host.

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Aim: Leukocyte-associated immunoglobulin-like receptor-1 (LAIR-1) is an immune inhibitory receptor which is expressed within most types of hematopoietic cells and negatively regulates immune responses. Recently, we found LAIR-1 expression to be present within tumors of nonhematopoietic lineages. However, the roles of LAIR-1 in hepatocellular carcinoma (HCC) have yet to be examined.

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