Publications by authors named "Leya Qu"

Long-term consumption of high-carbohydrate feed may adversely affect intestinal health of fish; however, the underlying roles remain ambiguous. This study examined the effects of varying carbohydrate levels on the intestinal flora of common carp and assessed how microbial metabolites influence intestinal health. Two hundred seventy common carps were chosen and distributed randomly into three groups that fed diets containing starch at levels of 15% (low-carbohydrate diet [LCD]), 28% (medium-carbohydrate diet [MCD]), and 45% (high-carbohydrate diet [HCD]) for 60 days.

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Article Synopsis
  • Isthmin-1 (Ism1) is an adipokine that influences glucose uptake and metabolism, and researchers cloned its sequence in common carp (Cyprinus carpio), analyzing its expression in various tissues.
  • The study found Ism1 encoded a protein with 458 amino acids and showed high similarity with goldfish; it was most expressed in the heart, with varying levels during glucose tolerance and high-carb/high-fat feeding tests.
  • In vivo and in vitro experiments indicated that Ism1 helps lower serum glucose levels by upregulating certain glucose metabolism-related genes while downregulating others, highlighting its role in glucose metabolism in common carp.
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The Yellow River carp (Cyprinus carpio haematopterus) is a vital economically farmed fish of the Cyprinidae family. With the development of intensive aquaculture, carp production has increased dramatically, leading to the frequent occurrence of various diseases. Cell lines are considered the most cost-effective resource for in vitro studies and are widely used for physiological and pathological studies because of accessibility and convenience.

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This study sought to examine the role of bile acids in the regulation of glucose and lipid metabolism, intestinal flora, and growth in high-fat diet-fed common carp ( L.). Fish (6.

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A 56-day feeding trial was conducted to investigate the effects of genistein on growth, lipid metabolism, antioxidant capacity, and immunity of common carp fed with high-carbohydrate or high-fat diets. Five diets were used to feed fish: control diet (5% fat; CO), high-fat diet (11% fat; HF), high-carbohydrate diet (45% carbohydrate; HC), and HF or HC diet with 500 mg/kg genistein (FG or CG). Results showed that final body weight (FW) and specific growth rate (SGR) were significantly reduced, but the supplementation with genistein resulted in higher values of FW and SGR than the HF or HC group.

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