Toxin-antidote systems are selfish genetic elements composed of a linked toxin and antidote. The toxin-antidote system in consists of a transmembrane toxin protein PEEL-1 which acts cell autonomously to kill cells. Here we investigate the molecular mechanism of PEEL-1 toxicity.
View Article and Find Full Text PDFCentromeric histones (CenH3s) are essential for chromosome inheritance during cell division in most eukaryotes. CenH3 genes have rapidly evolved and undergone repeated gene duplications and diversification in many plant and animal species. In Caenorhabditis species, two independent duplications of CenH3 (named hcp-3 for HoloCentric chromosome-binding Protein 3) were previously identified in C.
View Article and Find Full Text PDFAlthough most unicellular organisms reproduce asexually, most multicellular eukaryotes are obligately sexual. This implies that there are strong barriers that prevent the origin or maintenance of asexuality arising from an obligately sexual ancestor. By studying rare asexual animal species we can gain a better understanding of the circumstances that facilitate their evolution from a sexual ancestor.
View Article and Find Full Text PDFIn microbial communities, bacteria chemically and physically interact with one another. Some of these interactions are mediated by secreted specialized metabolites that act as either intraspecies or interspecies signals to alter gene expression and to change cell physiology. is a well-characterized soil microbe that can differentiate into multiple cell types, including metabolically dormant endospores.
View Article and Find Full Text PDFBacillus luciferensis is a Gram-positive, facultatively anaerobic, motile rod. Here, we report the first draft genome sequence, to our knowledge, of a B. luciferensis strain (CH01), which will provide useful information for Bacillus and soil bacteria research.
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