Publications by authors named "Lewis V Rodriguez"
Environ Mol Mutagen
July 2003
Article Synopsis
- MGP residues, or coal tars, are byproducts from historic gas production and have been shown to cause tumors in mouse liver and lung.
- A study was conducted on mouse pulmonary tumors for loss of heterozygosity (LOH) to understand the effects of these residues on cancer development.
- Analysis revealed that 30-40% of tumors had allelic losses on specific chromosomes, suggesting the potential existence of unknown tumor suppressor genes linked to lung cancer in mice.
