Publications by authors named "Lewis S Jones"

Biofabricating 3D cardiac tissues that mimic the native myocardial tissue is a pivotal challenge in tissue engineering. In this study, we fabricate 3D cardiac tissues with controlled, multidirectional cellular alignment and directed or twisting contractility. We show that multidirectional filamented light can be used to biofabricate high-density (up to 60 × 10 cells mL) tissues, with directed uniaxial contractility (3.

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Article Synopsis
  • - The COVID-19 pandemic has increased the demand for affordable and quickly available personal protective equipment (PPE), leading to the development of a modified snorkel mask that adds medical-grade filters and a 3D-printed adapter for enhanced protection.
  • - The mask offers full-face coverage, protecting the eyes, mouth, and nose, and effectively filters out airborne particles, including SARS-CoV-2, with a proven filtration efficiency reaching FFP2 standards (stopping at least 94% of airborne particles).
  • - This alternative mask is not only effective against particles smaller than 500 nm but is also economical, locally producible, and shows good resistance to various decontamination methods, helping alleviate the shortage of traditional F
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In this work, we present an injection molded soft total artificial heart (sTAH) produced from high-temperature vulcanizing silicone using an industrial metal injection mold. At 60 beats per minute, the sTAH exhibited a total cardiac output of over 16 L/min against physiological pressures on a mock circulation and was pumped continuously for 110,000 actuation cycles. Finite element analysis was used to identify stress concentrations within the sTAH, allowing an optimized design to be proposed.

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