Effect of concentric exercise-induced fatigue on proprioception, motor control and performance of the upper limb in handball players.

Background: The last phases of a competitive game are when shoulder injuries most commonly happen, and fatigue is thought to be a major contributing factor, perhaps because of reduced proprioception and motor control. The purpose of this study was to investigate the effect of concentric fatigue on proprioception, motor control, and performance of the upper limb in handball players.

Methods: Forty-six right-handed handball players (all males, age 26.

DEK::AFF2 Fusion Sinonasal and Skull Base Nonkeratinizing Squamous Cell Carcinoma: A Clinical Outcome Study Compared With Conventional Sinonasal Squamous Cell Carcinoma.

DEK::AFF2 fusion nonkeratinizing squamous cell carcinoma (NKSCC) is an emerging entity in the sinonasal tract, temporal bone, and skull base. However, the clinical behavior of these tumors has not been well studied. Here, we report the largest cohort of DEK::AFF2 carcinomas to determine if morphology, mitotic rate, and/or Ki-67 IHC are associated with patient outcomes, including a comparison with high-risk human papillomavirus (HPV)-associated and independent patients.

Digital mapping of resected cancer specimens: The visual pathology report.

Background: The current standard-of-care pathology report relies only on lengthy written text descriptions without a visual representation of the resected cancer specimen. This study demonstrates the feasibility of incorporating virtual, three-dimensional (3D) visual pathology reports to improve communication of final pathology reporting.

Materials And Methods: Surgical specimens are 3D scanned and virtually mapped alongside the pathology team to replicate grossing.

Mass spectrometric detection of neutrophil elastase cleaved corticosteroid binding globulin and its association with Asn347 site glycosylation, in septic shock patients.

Background: Corticosteroid-binding globulin (CBG) modulates tissue cortisol availability via modification of cortisol:CBG binding affinity in response to multiple factors, including neutrophil elastase (NE) cleavage of the reactive centre loop (RCL), converting high affinity CBG (haCBG) to low affinity CBG (laCBG). In vitro, glycosylation of the RCL at Asn347 affects NE cleavage susceptibility. To date, no direct measurement of laCBG, which would verify NE cleavage, has been reported.

Impacts of the Bonnet Carré Spillway on common bottlenose dolphins in the Mississippi Sound from 2010 to 2021.

In the last decade, the frequency of the use of the Bonnet Carré Spillway (BCS) to divert water from the Mississippi River by the United States Army Corps of Engineers (USACE) has dramatically increased. The BCS is designed to protect the city of New Orleans, Louisiana from levee breaches and devastating floods. In 2011 and 2019, during extreme flood events, the USACE diverted 6.

Fracture Dynamics in Silicon Anode Solid-State Batteries.

Solid-state batteries (SSBs) with silicon anodes could enable improved safety and energy density compared to lithium-ion batteries. However, degradation arising from the massive volumetric changes of silicon anodes during cycling is not well understood in solid-state systems. Here, we use X-ray computed microtomography to reveal micro- to macro-scale chemo-mechanical degradation processes of silicon anodes in SSBs.

I-RANT: Training session on a novel, scripted, bystander microaggression intervention tool for medical students.

Background: Microaggressions, subtle and often unintentional acts of hostility, have been recognized as a significant issue in healthcare, adversely affecting learners' emotional and physical well-being. Current strategies for addressing microaggressions are broad frameworks without empirical substantiation that leave learners without a clear direction for intervention. This study introduces a novel scripted, succinct, bystander intervention tool to combat microaggressions.

A brief effective screening protocol for identifying cataract patients with binocular vision anomalies.

Background: To compare the effectiveness of a brief binocular vision screening protocol to a comprehensive examination for detecting binocular vision anomalies before and after cataract surgery.

Methods: A comprehensive binocular vision test battery as a gold standard were administered on recruited patients before the first surgery and at the third visit after surgery on the second eye. A receiver operating characteristic (ROC) curve was plotted to illustrate the diagnostic ability of each test.

Real-world Clinical Outcomes and Prognostic Factors in Neuroendocrine Prostate Cancer.

Background: Neuroendocrine prostate cancer (NEPC) encompasses pure NEPC and tumors with mixed adenocarcinoma and neuroendocrine histology. While NEPC is thought to confer a poor prognosis, outcome data are sparse, making risk stratification and treatment decisions difficult for clinicians.

Methods: This retrospective study identified patients with morphological and/or immunohistochemical NEPC features on pathological review of high-grade prostate cancer cases.

Genome sequences of two phages isolated from wastewater treatment samples that infect a clinical isolate.

We announce the complete genomes of phages ValerieMcCarty03 and ValerieMcCarty04 isolated from wastewater treatment plant samples that infect a multidrug-resistant clinical isolate. These phages belong to the T4-like cluster and fall within the genus.

Recognizing Variations in Primary Palatoplasty Billing: A Review of 9827 Cases.

Objective: Identify unbundling trends in primary palatoplasty.

Design: Retrospective study utilizing the American College of Surgeon Pediatric National Surgical Quality Improvement Program (PNSQIP).

Setting: Records available from 2016 to 2021.

"It's not a pain you can fix": A qualitative exploration of working with vulnerably positioned current and bereaved carers across sectors of health and social care.

Caring for someone with a life-limiting illness is associated with complex psychosocial sequelae; amplified for carers experiencing structural vulnerability. Workers across sectors of health and social care provide support for vulnerably positioned carers, yet exploration of the impacts of this work has predominantly focused on health professionals directly engaged with death and dying. This qualitative study explored ways in which palliative care and welfare workers experience work with current and bereaved carers of people with life-limiting illness, in a region associated with socioeconomic disadvantage.

Bilateral Cochlear Implants and Bimodal Hearing: A Comparison of Quality of Life.

Background:  Despite significant advances in the field of cochlear implants (CIs), there is no widely accepted criterion for when to counsel on bilateral CIs in adults. This is partly due to conflicting findings on the advantages of bilateral CIs versus bimodal hearing (i.e.

Semaglutide and Postoperative Outcomes in Non-Diabetic Patients Following Body Contouring Surgery.

Background: Semaglutide is a medication used for weight loss in obese patients. Recently, many plastic surgeons have recommended its use of semaglutide following bariatric surgery to increase one's weight loss. However, postoperative complications such as wound dehiscence, delayed healing, and infection pose significant risks.

Bio-Interventional Cyclodialysis and Allograft Scleral Reinforcement for Uveoscleral Outflow Enhancement in Open-Angle Glaucoma Patients: One-Year Clinical Outcomes.

Background: To evaluate the one-year safety and effectiveness of bio-interventional cyclodialysis and scleral reinforcement in open-angle glaucoma (OAG) patients undergoing cataract surgery.

Methods: An ab-interno approach was used to create a sectoral cyclodialysis in OAG patients who were prospectively followed in a consecutive case series. Subsequent visco-cycloplasty with scleral reinforcement using homologous minimally modified allograft scaffold was completed to maintain patency of the cyclodialysis reservoir and increase uveoscleral outflow.

National partnerships address critical needs in infection prevention and control.

The COVID-19 pandemic highlighted gaps in infection control knowledge and practice across health settings nationwide. The Centers for Disease Control and Prevention, with funding through the American Rescue Plan, developed Project Firstline. Project Firstline is a national collaborative aiming to reach all aspects of the health care frontline.

New York State Climate Impacts Assessment Chapter 04: Buildings.

New York State has nearly 5.3 million buildings, and all of them are vulnerable in some way to the impacts of climate change. Understanding these impacts is critical, because risks to buildings not only threaten individual lives but also pose threats to community-level resilience.

Visual pathology reports for communication of final margin status in laryngeal cancer surgery.

Background: Positive margins are frequently observed in total laryngectomy (TL) specimens. Effective communication of margin sampling sites and final margin status between surgeons and pathologists is crucial. In this study, we evaluate the utility of multimedia visual pathology reports to facilitate interdisciplinary discussion of margin status in laryngeal cancer surgery.

Correction: Problem-solving interventions and depression among adolescents and young adults: A systematic review of the effectiveness of problem-solving interventions in preventing or treating depression.

[This corrects the article DOI: 10.1371/journal.pone.