Synopsis of recent research by authors named "Lewins Walter"
- Lewins Walter's recent research focuses on the interactions between oral epithelial cells and the SARS-CoV-2 virus, revealing that cells expressing low levels of angiotensin-converting enzyme 2 are particularly susceptible to infection.
- His investigations into familial adenomatous polyposis (FAP) indicate that combining sulindac (a nonsteroidal anti-inflammatory drug) with bexarotene (a rexinoid) may effectively reduce polyp formation and prevent colorectal cancer in FAP patients.
- The studies on matrix metalloproteinases (MMP9) demonstrate their complex role in colitis-associated cancer, where MMP9 both mediates inflammation and acts protectively by maintaining epithelial barrier function, suggesting new therapeutic targets for inflammatory bowel disease-related cancers.
