New observations on three cases of ossifying fibromyxoid tumor of soft parts.

Three cases of a recently established entity named "ossifying fibromyxoid tumor of soft parts" (OFMT) were studied histologically, ultrastructurally and by immunohistochemistry. All three tumors were stated in women from 48 to 54 years of age. One tumor was situated superficially in the skin and subcutaneous tissue.

[Familial dilated cardiomyopathy with autosomal mode of inheritance. Case report].

Familial occurrence of dilated cardiomyopathy is estimated by 2-20%. We present a family with dilated cardiomyopathy inherited in an autosomal dominant way. We examined 9 members of the family, most of them are asymptomatic.

Stress-induced injury of pig myocardium is accompanied by increased lipid peroxidation and depletion of mitochondrial ATP.

The aim of the study was to investigate the mechanisms of myocardial lesions induced by stress in conscious, intact pigs. The animals were subjected to 24 h immobilization, controls were kept in normal conditions. The pigs were killed by electric shock and exsanguination.

Prognostic significance of certain factors in the haemolytic-uraemic syndrome.

The prognostic significance of certain factors in the outcome of the haemolytic-uraemic syndrome (HUS) was evaluated. Seventy-three children with HUS were observed; 35 recovered without residual abnormalities, 6 had normal renal function with hypertension (HT) and/or urinary abnormalities, 5 had chronic renal failure, 1 child required chronic dialysis treatment, 4 children died of end-stage renal failure, and 22 died of acute renal failure (ARF). To identify the risk factors which influence prognosis, a logistic discrimination method was used to analyse the clinical and laboratory data.

Studies on the regeneration of rat intestinal epithelium after exposure to cyclophosphamide.

Cyclophosphamide caused changes in Paneth cells. The relationship of these changes to the proliferative reaction of the intestinal epithelium requires a more complete knowledge of various physiological functions of Paneth cells.

Effect of nisoldipine on stress-induced myocardial damage in the conscious pig.

1. The effect of the calcium channel blocker nisoldipine on the myocardial content of lipid peroxidation products (malondialdehyde (MDA), conjugated double bonds (CDB), fluorescent end-products (RF) and mitochondrial adenine nucleotides) was investigated in conscious pigs (n = 14) subjected to 24 h of immobilization stress. Histoenzymatic and electron microscopic studies of the myocardium were also performed.

Acute lymphoblastic leukemia in children below two years of age.

From among 1464 children with ALL 167 (11.4%) at diagnosis had two or less than two years, 53 of them were infants. Most of them had a great tumor bulk, 15 had initial CNS infiltration and 31 WBCc greater than or equal to 100000/ML.

Intestinal epithelium regeneration in rats receiving methotrexate and a trial of regulating this regeneration with pentagastrin and glucagon.

The study was carried out in three groups of rats: group I of 36 rats received methotrexate, group II of 36 rats were given methotrexate, pentagastrin and glucagon, group III of 12 rats served as control. For histological examination the ileum was taken from the animals killed on days 1, 2, 3, 4, 7 and 9 after the last injection of methotrexate. Besides histological examinations the mitotic index and the number of cells in crypt longitudinal-section were determined.

[Dynamics of lesions to the myocardium in experimental hyper- cholesterolemia].

Dynamics of changes in the myocardium of rabbits subjected to food hypercholesterolemia lasting from 6 to 16 weeks was investigated. An intensification of coronary atheromatosis was proportional to the duration of the high-cholesterol diet. There were observed focal and growing in time damages of cardiomyocytes.