Publications by authors named "Lewei Jin"
Article Synopsis
- Limited treatment options for breast cancer brain metastases (BCBM) highlight the need for new therapies, leading researchers to investigate an engineered oncolytic herpes simplex virus (oHSV) that expresses an anti-CD47 monoclonal antibody.* -
- The combination of this engineered virus (OV-αCD47-G1) with the chemotherapy drug temozolomide (TMZ) showed improved effectiveness in preclinical models, increasing macrophage and NK cell activity against breast tumor cells.* -
- Results indicated that this combination therapy not only enhanced immune response but also significantly extended survival in tumor-bearing mice, suggesting potential benefits for BCBM patients.*
Backgrounds: 3D simulation is increasingly used in rhinoplasty. However, during the operation, there is no tool to directly link the 3D simulation results with the intraoperative operation. Doctors rely on 3D simulation results only according to their intuition.
View Article and Find Full Text PDFBackground Aims: Several studies have shown the efficacy of mesenchymal stem cell (MSC) therapy for lower extremity vascular disease (LEVD) in diabetic patients, but the results are not consistent. Therefore, the authors conducted a meta-analysis of randomized controlled trials (RCTs) to examine the safety and efficacy of MSC therapy in diabetic patients with LEVD.
Methods: Eight available databases were searched in both English and Chinese to identify RCTs comparing MSC therapy-based conventional treatment with conventional treatment alone in diabetic patients with LEVD.
Background: Scars exposed on the body surface lead to a large psychological burden on patients. However, no satisfactory scar treatments exist. Botulinum toxin type A is a neurotoxin that has been widely applied in the plastic and cosmetic surgery field.
View Article and Find Full Text PDF