Publications by authors named "Levy-Bohbot N"
Context: Multiple endocrine neoplasia Type-1 (MEN1) in young patients is only described by case reports.
Objective: To improve the knowledge of MEN1 natural history before 21 years old.
Methods: Obtain a description of the first symptoms occurring before 21 years old (clinical symptoms, biological or imaging abnormalities), surgical outcomes related to MEN1 Neuro Endocrine Tumors (NETs) occurring in a group of 160 patients extracted from the "Groupe d'étude des Tumeurs Endocrines" MEN1 cohort.
Article Synopsis
- - The study investigates the long-term effectiveness of different surgical methods for patients with insulinomas related to Multiple Endocrine Neoplasia type 1 (MEN1), analyzing data from surgeries performed between 1957 and 2010.
- - Out of 73 patients analyzed, distal pancreatectomy (DP) was found to have the lowest risk of recurrent hypoglycemia compared to total pancreatectomy/cephalic duodenopancreatectomy (TP/CDP) and enucleation (E).
- - Although E showed no long-term complications, DP was prioritized due to its lower recurrence rate of hypoglycemia, suggesting it as the best surgical option for these patients.
[Chronic use of proton-pump inhibitors associated with giardiasis: A rare cause of hypomagnesemic hypoparathyroidism?].
Ann Endocrinol (Paris)
November 2008
Hypomagnesemia is a rare cause of hypoparathyroidism that can have a very serious clinical presentation. We report the case of a 62-year-old woman hospitalized for exploration of acute tetraparesis with vomiting and swallowing disorders associated with a severe hypocalcemia. Biological explorations revealed hypoparathyroidism (PTH=16ng/L) related to low plasma and erythrocyte magnesium (0.
View Article and Find Full Text PDFDigestive calcitonin-secreting tumors of the foregut: comparison with non-calcitonin-secreting tumors.
Eur J Gastroenterol Hepatol
September 2006
Objectives: Digestive calcitonin-secreting endocrine tumors are very rare lesions of the foregut. This study was undertaken to compare the characteristics and the prognosis of these tumors and those of non-calcitonin-secreting endocrine tumors.
Methods: All patients with a digestive endocrine tumor of the foregut followed up in Reims University Hospital and whose serum calcitonin levels were determined between 1988 and 2004 were included.
Purpose: Today, calcitonin assay is used for the diagnosis of thyroid medullary cancer in the context of nodular thyroid disease. Calcitonin is an excellent marker of thyroid medullary cancer but some hypercalcitoninemia can also be related to other diseases, such as renal failure, endocrine tumors other than thyroid medullary cancer and sometimes to C cell hyperplasia, which is a not well-defined situation. Recent studies contributed to define calcitoninemia thresholds, which guide decision and avoid excessive invasive treatment.
View Article and Find Full Text PDFUnlabelled: Few studies have concerned the rare functioning endocrine pancreatic tumors associated with multiple endocrine neoplasia type 1 (MEN 1). When sporadic, these tumors have a poor prognosis.
Aim: To analyze the frequency, characteristics and prognosis of MEN 1-associated glucagonomas, VIPomas and somatostatinomas recorded in the GTE (Groupe des Tumeurs Endocrines) registry.