A systematic review of quality and consistency of clinical practice guidelines on the primary prevention of food allergy and atopic dermatitis.

Background And Aims: With an increasing number of Clinical Practice Guidelines (CPGs) addressing primary prevention of food allergy and atopic dermatitis, it is timely to undertake a comprehensive assessment of the quality and consistency of recommendations and evaluation of their implementability in different geographical settings.

Methods: We systematically reviewed CPGs from 8 international databases and extensive website searches. Seven reviewers screened records in any language and then used the AGREE II and AGREE REX instruments to critically appraise CPGs published between January 2011 and April 2022.

Food Proteins in Human Breast Milk and Probability of IgE-Mediated Allergic Reaction in Children During Breastfeeding: A Systematic Review.

Background: Previous reports suggested that food proteins present in human milk (HM) may trigger symptoms in allergic children during breastfeeding, but existing evidence has never been reviewed systematically.

Objective: To assess the probability of food proteins in HM to trigger allergic reactions in infants with IgE-mediated food allergy.

Methods: Electronic bibliographic databases (MEDLINE, EMBASE) were systematically searched from inception to November 3, 2021.

Stargardt disease-associated mutation spectrum of a Russian Federation cohort.

ABCA4-associated mutation screening is extensively performed in European, African, American and several other populations for various retinopathies. However, it has not been well studied in a Russian cohort. Using next-generation (325 genes inherited disease panel) and Sanger sequencing technologies for the first time we documented the spectrum of genetic variations in a Russian retinopathy cohort of 51 patients from 10 ethnic groups.

Blind normalization of speech from different channels.

We show how to construct a channel-independent representation of speech that has propagated through a noisy reverberant channel. This is done by blindly rescaling the cepstral time series by a nonlinear function, with the form of this scale function being determined by previously encountered cepstra from that channel. The rescaled form of the time series is an invariant property of it in the following sense: It is unaffected if the time series is transformed by any time-independent invertible distortion.

[Development and study of an experimental herpesvirus vaccine].

The strains suitable for the development of herpesvirus vaccine were selected as a result of studies on numerous herpes virus strains isolated from patients with relapsing herpes infection of various localizations. Infectious tissue culture antigens were obtained by roller cultivation of chick embryo fibroblast cultures infected with herpesvirus in the presence of 0.2% human serum albumin.

Use of duck embryo cell cultures for the study of arbovirus reproduction.

Duck embryo cell (DEC) cultures were used for the study of arbovirus reproduction. High sensitivity of DEC cultures to Japanese encephalitis, West Nile, Tyuleniy, Sakhalin and Baku viruses was established. DEC cultures are recommended for investigation of arbovirus reproduction.

[Cultivation of reovirus in human embryonic organ cultures].

Human embryo lung and intestine organ cultures were infected with reovirus type 3 isolated from the lungs of a newborn baby. In the lung organ culture the virus multiplied quite intensively producing in the bronchi characteristic 4-6 nuclei cells.

[A comparative study of primary human cell cultures of diffuse goiter and cancer of the thyroid gland].

Cells obtained from non-malignified tissues (diffuse struma) in 83 of 100 cases formed a continuous layer consisting of monomorphous epithelioid cells possessing a high adhesive capacity. Cells obtained from thyroid adenocarcinoma (in 5 of 7 cases) showed lowered adhesiveness and did not form a monolayer. The culture consisted of polymorphous cells.