Publications by authors named "Levent Ozturk"
Retrospective Evaluation of Anesthesia in Patients Undergoing Surgery after the February 6, 2023 Earthquake in Turkey.
Disaster Med Public Health Prep
January 2025
Throughout human history, numerous natural disasters, particularly earthquakes, have caused significant destruction to civilizations. On February 6, 2023, 2 major earthquakes struck Turkey. The first occurred at 04:17 local time with a magnitude of 7.
View Article and Find Full Text PDFPreoperative preparation and postoperative care in children in thoracic surgery.
Turk Gogus Kalp Damar Cerrahisi Derg
January 2024
Article Synopsis
- Pediatric patients have unique anatomical and physiological differences from adults, making their anesthesia for thoracic surgery distinctive.
- Proper preoperative preparation, effective tool selection for one-lung ventilation, and good pain management are crucial for improved postoperative care.
- This review will cover the perioperative anesthesia management for these patients, focusing on preoperative steps and the challenges of one-lung ventilation.
The effect of 24-hour sleep deprivation on subjective time perception.
Int J Psychophysiol
October 2023
In this study, we investigated the effect of 24-h total sleep deprivation on subjective time perception. Twenty-five participants aged 18-35 years (13 female and 12 male) were recruited. Time perception and cognitive assessments were performed twice: after a regular night's sleep and following a 24-h sleep deprivation.
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- Saddle block anesthesia (SBA) is commonly used for outpatient anorectal surgeries, and this study compared two doses of hyperbaric bupivacaine to assess their impact on recovery time and block characteristics.
- Patients aged 18 and over were divided into two groups: those receiving 5 mg and those receiving 3 mg of bupivacaine, focusing on discharge times and several secondary outcomes like sensory block duration and side effects.
- Results showed that the 3 mg group had faster recovery with shorter discharge and voiding times, indicating that lower doses of hyperbaric bupivacaine could be a better option for reducing complications and improving patient outcomes.
Article Synopsis
- - This study aimed to examine how one night of sleep deprivation impacts cognitive function in healthy young adults aged 18-30.
- - Twenty-one participants were tested on cognitive assessments before and after a night without sleep, compared to a control group that had normal sleep.
- - Results showed no significant changes in cognitive performance due to sleep deprivation, suggesting that a single night without sleep may not significantly affect cognitive abilities in healthy individuals.
Article Synopsis
- This study evaluated the effectiveness of the Sleep Disturbance Scale for Children (SDSC) for Turkish-speaking children by translating and validating the tool.
- A sample of 1903 children aged 5-15 participated, with assessments conducted through questionnaires filled out by their parents.
- The findings highlighted that the Turkish version of SDSC is both valid and reliable, showing high internal consistency and revealing a 4.15% prevalence of sleep disorders, mainly sleep hyperhidrosis.
Article Synopsis
- Recent studies show that sleep deprivation (SD) is a modifiable risk factor for hypertension, but the mechanisms behind this link are not fully understood.
- The study tested how SD affects blood pressure responses in healthy young males through various cardiac stress tests over three consecutive days.
- Results indicated that one night of SD impaired blood pressure reactivity to stress tests, although resting blood pressure levels remained unchanged, emphasizing the role of sleep in blood pressure regulation.
Repeated Doses of Ketamine Affect the Infant Rat Urogenital System.
Drug Des Devel Ther
October 2021
Article Synopsis
- - This study investigates the impact of long-term ketamine use on various organs, specifically focusing on potential damage to the kidneys, testicles, epididymis, and ductus deferens, in addition to the previously known bladder issues.
- - Male Wistar Albino rats were divided into two groups, one receiving ketamine and the other saline, for three weeks, after which their kidney and testicular tissues were analyzed for biochemical and histopathological changes.
- - Results indicated significant kidney and testicular damage in the ketamine group, marked by increased tissue congestion and altered enzyme activity, suggesting further clinical and research exploration is needed regarding the effects of repeated ketamine administration in medical settings.
Feed Composition Differences Resulting from Organic and Conventional Farming Practices Affect Physiological Parameters in Wistar Rats-Results from a Factorial, Two-Generation Dietary Intervention Trial.
Marcin Barański Dominika Średnicka-Tober Leonidas Rempelos Gultakin Hasanaliyeva Joanna Gromadzka-Ostrowska Levent Ozturk
Nutrients
January 2021
Article Synopsis
- Recent studies indicate that eating organic food may be linked to lower rates of obesity, cancer, and other diseases, but research supporting these claims is limited.
- A two-generation study with male Wistar rats examined how organic versus conventional feed affected growth, hormone levels, and immune responses, focusing on the impact of synthetic pesticides and fertilizers.
- Results showed significant differences in feed composition based on crop protection methods, leading to notable effects on feed intake, weight gain, and immune function, highlighting the complex interactions between diet and health outcomes.
Article Synopsis
- The study aimed to assess the impact of wearing FFP3 masks on venous blood gases and subjective symptoms in healthcare professionals.
- After 4 hours of mask usage, venous blood gas levels remained stable, with no significant changes detected.
- Although participants reported various symptoms like headaches and lightheadedness, the overall findings suggested that FFP3 masks were tolerated well without causing major discomfort.
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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- - The study explored the effects of cannabinoid systems and nesfatin-1 on sleep, metabolism, and food intake, specifically focusing on 72-hour REM sleep deprivation in mice and the role of specific cannabinoid receptors (CB1R and CB2R).
- - Mice were divided into different groups and received various injections to assess changes in nesfatin-1 levels and insulin resistance, with results indicating that cannabinoid treatment decreased brain nesfatin-1 positivity while blocking receptors prevented this reduction.
- - Findings suggested that increased insulin resistance was linked to CB2 receptor activation, which occurred independently of changes in central nesfatin-1 levels, indicating a complex interaction between these systems.
Article Synopsis
- The study compares the impact of two inhalation anesthetics, desflurane and sevoflurane, on oxidative status during laparoscopic cholecystectomy by evaluating thiol-disulfide homeostasis.
- It involved 71 patients who were divided into two groups, with blood samples collected at three different times to measure various thiol levels and ratios.
- The results indicated that sevoflurane showed a more significant reduction in oxidative stress markers, suggesting it may be more protective against oxidative damage during surgery than desflurane.
Article Synopsis
- - Agricultural intensification has boosted cereal yields over the past 40 years, but its impact on crop health and quality is not well understood.
- - The study found that mineral NPK fertilizers lower phenolic acid and flavonoid levels in wheat leaves, making them more prone to lodging and powdery mildew compared to composted FYM inputs.
- - While herbicides and fungicides help reduce lodging and disease, they don’t affect phenolic concentrations; using composted FYM may reduce grain yields without significantly controlling pathogens like Septoria.
Article Synopsis
- The study examines how the prestin gene might be involved in hearing loss caused by salicylate, a common drug, by looking at DNA methylation changes in guinea pigs.
- Fifteen guinea pigs were tested for hearing ability after being given either saline or sodium salicylate, with significant decreases in hearing function observed shortly after salicylate injections.
- Results indicated that while DNA methylation levels increased during the initial exposure to salicylate, they returned to normal over time, suggesting a link between these methylation changes and temporary hearing loss.
Article Synopsis
- Soil salinization and degradation due to climate change is a significant challenge for wheat production, necessitating the identification of salt tolerance genes and marker-assisted selection (MAS) for effective breeding.
- Researchers genotyped 154 wheat lines using a high-density linkage map, resulting in the identification of 49 quantitative trait loci (QTLs) associated with salt tolerance, including key QTLs for sodium exclusion on specific chromosomes.
- The study also mapped additional QTLs for essential mineral concentrations under salinity, revealing the genetic basis for salt tolerance and providing valuable insights for future breeding programs aimed at improving wheat resilience to salinity.
Article Synopsis
- Seed size and composition, crucial for soybean yield, are influenced by soil nutrient levels, particularly phosphorus (P), which is vital but non-renewable.
- A study using soybean recombinant inbred lines (RILs) revealed that while seed weight and number varied significantly with phosphorus availability, seed composition remained consistent even in low-P conditions.
- The identification of multiple quantitative trait loci (QTLs) for seed weight and protein under low-P environments highlights genetic regions that could enhance soybean growth in nutrient-poor soils, with heritability estimates suggesting strong potential for breeding.
Article Synopsis
- - The study investigates how medial olivocochlear efferent (MOCE) neurons affect outer hair cells in the cochlea, potentially influencing sound frequency discrimination independently from sound waves.
- - Eleven guinea pigs were tested using otoacoustic emissions and pure-tone acoustic trauma to evaluate cochlear response and OHC damage, with SEM examining the organ of Corti.
- - Results showed that even with OHC damage in one ear, the contralateral ear could still exhibit frequency-specific sound responses, suggesting MOCEs play a role in transmitting acoustic information between damaged and intact regions.
Article Synopsis
- - The study investigates healthy individuals' views on how much they should know about the serious risks associated with surgeries, revealing a mix of awareness and consent issues among participants.
- - Of the 330 surveyed, only 23.5% were fully informed about their surgical complications, with 44.9% lacking any preoperative consent regarding these risks; most expressed a desire for better information.
- - The findings suggest that involving relatives during the consent process could enhance patients' understanding and retention of surgical risks, as many participants preferred having a family member present when discussing potential complications.
Article Synopsis
- The study aimed to compare the effects of an interscalene brachial plexus block using bupivacaine or levobupivacaine along with general anesthesia on desflurane consumption in patients undergoing arthroscopic shoulder surgery.
- The research involved 60 patients, who were randomly assigned to receive either general anesthesia alone or in combination with one of the two blocks, measuring various recovery and pain-related outcomes.
- Results showed that both bupivacaine and levobupivacaine groups used less desflurane compared to the general anesthesia-only group, leading to quicker recovery times and better pain management post-surgery.
Article Synopsis
- This trial hypothesizes that cementless hemiarthroplasty will be better than cemented versions for elderly patients with femoral neck fractures, specifically looking at survival rates and complications.
- The study involved ASA class III patients aged 70 and older, divided into two groups: one receiving cementless surgery (Group A) and the other undergoing surgery with cement (Group B), with follow-ups averaging around 47 months.
- Results showed that cementless procedures had shorter operation times and lower intensive care unit stays, with fewer complications and better early outcomes, indicating cementless methods are at least as effective as cemented ones in treating these fractures.
Article Synopsis
- Malnutrition is prevalent in ICU patients and careful monitoring and management can significantly enhance their recovery.
- Enteral feeding is preferred over parenteral feeding due to its physiological benefits and lower risk of complications.
- A study of 198 ICU patients indicated that while most received nutritional support, many did not show improved albumin levels, highlighting the need for thorough nutritional assessments for effective treatment.
Article Synopsis
- - The study aimed to explore the differences in peak oxygen consumption (VO(2peak)), anaerobic test results, and knee muscle strength among different GNB3 genotype groups in male basketball players.
- - Seventy-two male athletes were divided into three genotype groups (CC, CT, TT) based on a specific GNB3 gene polymorphism and various performance metrics were compared among them.
- - Results showed that the TT genotype group performed worse in several measurements, indicating that the 825T-allele might negatively influence athletic performance and could act as a genetic predictor of lower performance in basketball players.