Effects of clonidine and dopamine on gastric tone.

Background And Objective: The effects of clonidine and dopamine, both alone and together, on gastric tone were studied using an electronic barostat. This enabled volume changes to be measured in an intragastric bag with a constant preset pressure.

Methods: Nine healthy male volunteers were each studied on two occasions in a randomized order.

Dopamine reduces gastric tone in a dose-related manner.

Background: Dopamine may have effects on gastrointestinal motility. The aim of this study was, therefore, to determine whether dopamine reduces gastric tone and whether the effects of dopamine can be blocked by a dopamine antagonist.

Methods: Eight healthy male volunteers were studied on two occasions in a randomized order.

Dopamine delays gastric emptying and prolongs orocaecal transit time in volunteers.

Dopamine decreases gastric tone and may therefore influence gastrointestinal motility. The aim of this investigation was to study the effects of a continuous infusion of dopamine on gastric emptying and orocaecal transit time. Nine healthy male volunteers were studied on two occasions in a randomized order.