Comparing Multivisceral Resection with Tumor-only Resection of Liposarcoma Using the Win Ratio.

Background: Multivisceral resection of retroperitoneal liposarcoma (LPS) is associated with increased morbidity and may not confer a survival benefit compared with tumor-only (TO) resection. We compared both approaches using a novel statistical method called the "win ratio" (WR).

Methods: Patients who underwent resection of LPS from 2004 to 2015 were identified from the National Cancer Database.

Liver Transplant as a Treatment of Primary and Secondary Liver Neoplasms.

Importance: Liver malignancies are an increasing global health concern with a high mortality. We review outcomes following liver transplant for primary and secondary hepatic malignancies.

Observations: Transplant may be a suitable treatment option for primary and secondary hepatic malignancies in well-selected patient populations.

Locoregional Therapy for Intrahepatic Cholangiocarcinoma: The Role of Intra-Arterial Therapies.

Intrahepatic cholangiocarcinoma (ICC) is a rare disease with a rising incidence. While surgical resection is the only curative option, the disease process is often identified in advanced stages, as this malignancy often remains clinically silent in early development. Only one-third of patients are eligible for resection at the time of diagnosis.

Dermatofibrosarcoma protuberans: a case report of an abdominal wall mass and review of the literature.

Dermatofibrosarcoma protuberans (DFSP) is a rare, slow-growing malignancy that often presents with an ambiguous clinical presentation due to its nonspecific findings. We present the case of a 41-year-old male who presented with a slow-growing mass on his abdomen that became protuberant and firm, prompting his desire to pursue excision. Upon return of histologic examination, the specimen was noted to be DFSP.

Mutational Landscape and Precision Medicine in Hepatocellular Carcinoma.

Hepatocellular carcinoma (HCC) is the fourth most common malignancy worldwide and exhibits a universal burden as the incidence of the disease continues to rise. In addition to curative-intent therapies such as liver resection and transplantation, locoregional and systemic therapy options also exist. However, existing treatments carry a dismal prognosis, often plagued with high recurrence and mortality.

Syringocystadenoma papilliferum: case series and review of the literature.

Syringocystadenoma papilliferum (SCAP) is a rare, hamartomatous tumor of the apocrine glands, which typically manifests in the head and neck region. We present a case of 60-year-old male with a several-year history of the lesion located on the abdominal wall and a second case of a 58-year-old male with a history of a slow-growing lesion located on the tragus. Despite varying presentations and locations, both patients were identified to have SCAP on pathological evaluation.

Hamartomatous polyps: Diagnosis, surveillance, and management.

Hereditary polyposis syndrome can be divided into three categories: Ade-nomatous, serrated, and hamartomatous polyps. Hamartomatous polyps, malformations of normal tissue presenting in a disorganized manner, are characterized by an autosomal dominant inheritance pattern. These syndromes exhibit hamartomatous gastrointestinal polyps in conjunction to extra-intestinal manifestations, which require conscientious and diligent monitoring.

Surgical Treatment of Distal Cholangiocarcinoma.

Distal cholangiocarcinoma (dCCA) is a rare malignancy arising from the epithelial cells of the distal biliary tract and has a poor prognosis. dCCA is often clinically silent and patients commonly present with locally advanced and/or distant disease. For patients identified with early stage, resectable disease, surgical resection with negative margins remains the only curative treatment strategy available.

Adenoid Cystic Carcinoma of the Breast: A Case Report.

Adenoid cystic carcinoma (ACC), characterized by proliferating glands and stromal and basement membrane elements, is a tumor most commonly occurring in the salivary glands; very rarely does this tumor present as a primary tumor in the breast. We present the case of a 53-year-old female who presented with a breast mass noted to be concerning on imaging and confirmed to be ACC on biopsy. The mass was amenable to surgical excision with referrals to medical and radiation oncology.

Flood syndrome: a rare case of spontaneous rupture of umbilical hernia in a cirrhotic patient.

Flood syndrome is a rare and potentially fatal complication of long-standing ascites resulting from a spontaneous rupture of an umbilical hernia. We present the case of a 67-year-old male with a medical history of diastolic heart failure, cocaine abuse, hepatitis C and cirrhosis secondary to daily alcohol consumption who presented to the emergency department with spontaneous rupture of an umbilical hernia with continuous, perfuse drainage of ascites from a 3 cm hernia defect. In this case report, we highlight the successful temporizing and definitive management of flood syndrome, as the patient presented to and was temporized a community hospital and was subsequently transferred to a tertiary care center for definitive management.

Blunt cerebrovascular injury of cervical and petrous ICA with stroke: A case study.

This case report documents treatment of a 32-year-old male patient after being extricated from an extensively damaged motor vehicle after a collision. On first presentation, the patient had a Glascow Coma Score of 14 and a pan-scan revealed a severely comminuted fracture of the proximal left femoral shaft, a fracture of the left patella, and multiple rib fractures. A neurological exam on a later evaluation showed global aphasia and sharp decline in movements of the right upper and lower extremities even with painful stimuli.

A case of sporadic Peutz-Jeghers syndrome presenting as multiple intussusceptions.

Peutz-Jeghers syndrome (PJS) is an autosomal dominant mutation of the STK11/LKB1 gene on chromosome 19 often characterized by mucocutaneous pigmentation, hamartomatous polyps, anemia, gastrointestinal bleeding and intussusception. We present the case of a 21-year-old female with no pertinent family history who received the diagnosis of PJS after presenting to the hospital with two episodes intussusception. Patients with PJS have an increased lifetime risk of developing stomach, small bowel, colon, pancreatic, breast, cervical, uterus and testicular cancer requiring religious surveillance at an early age.

Case report-successful management of acute buried bumper syndrome.

Percutaneous gastrostomy (PEG) tube placement is often the preferred approach to addressing nutritional deficits in patients requiring long-term feeding access. Numerous major and minor complications may occur with PEG tube insertion; buried bumper syndrome is a rare, long-term outcome of PEG tube placement, comprising <2.4% of complications.