Is intraoperative margin sampling necessary in inverted papilloma resection?

Purpose: To explore the association between intraoperative surgical margin sampling by the frozen sections and recurrence in inverted papilloma surgery.

Methods: A multicenter, retrospective study of patients who underwent attachment-oriented IP resection in four tertiary care medical centers with a minimal follow-up of 36 months.

Results: The study included 220 surgeries with a mean follow-up period of 49 months (range 36-204).

Can Computed Tomography Findings Predict the Recurrence of Sinonasal Inverted Papilloma?

Objective: To evaluate the correlation between the ability to predict the attachment site of sinonasal inverted papilloma by computed tomography and the long-term surgical outcome.

Study Design: Retrospective cohort study.

Setting: Five tertiary medical centers.

Recurrent pleomorphic adenoma: is treatment considerably delayed thus affecting surgical morbidity?

Objective: To examine the incidence of late presentation of patients with recurrent pleomorphic adenoma (RPA) of the parotid gland.

Methods: This is a retrospective analysis of patients treated in our center. We examined patients demographics, disease characteristics, treatment, and outcome and as well as the time period length from the first discovery of a recurrent mass until seeking treatment at our clinic and its effect on morbidity.

Prognostic Factors in Differentiated Thyroid Cancer Revisited.

Background: More than 90% of all thyroid cancers are differentiated thyroid carcinomas (DTC) with a 10 year survival rate greater than 90%. The commonly used risk stratification systems for DTC include: European Organization for Research and Treatment of Cancer (EORTC), AGES (Age, histologic Grade, Extent of tumor, Size), AMES (Metastasis) and MACIS (Completeness of resection, local Invasion). Other systems are also utilized.

Acute Invasive Fungal Rhinosinusitis in Children With Hematologic Malignancies: Outcome of Surgical Treatment.

The incidence of acute invasive fungal rhinosinusitis (AIFR) is rising due to more aggressive chemotherapy and longer survival of immunosuppressed patients. Early diagnosis and appropriate but nonmutilating surgical treatment are particularly problematic in the pediatric population. This study aimed to evaluate the outcome of surgery for pediatric AIFR.

Delayed Sino-nasal Complications of Radiotherapy for Nasopharyngeal Carcinoma.

Objective: There are only sporadic reports of delayed sino-nasal complications associated with nasopharyngeal carcinoma (NPC) treated with radiotherapy. These include choanal stenosis, osteoradionecrosis, chronic sinusitis, and intranasal synechiae. Most likely, these complications are underestimated as in many institutions nasal endoscopies in NPC patients are not performed routinely.

Relation between preoperative computed tomographic criteria of injury to the nasofrontal outflow tract and operative findings in fractures of the frontal sinus.

Injury to the nasofrontal outflow tract is important in the treatment of fractures of the frontal sinus. In 2008 preoperative computed tomographic (CT) criteria or signs of such injuries were proposed and stated to be reliable. The aim of this study was to evaluate the validity of these criteria by comparing the radiological evidence with the operative findings.

Secondary tracheoesophageal puncture and myotomy--A novel outpatient technique.

Background: The purpose of this study was to show a novel technique for secondary tracheoesophageal puncture (TEP) and myotomy in patients who previously underwent total laryngectomy.

Methods: Fifteen patients underwent secondary TEP and 3 patients underwent myotomy. In 1 patient, both myotomy and TEP were done concurrently.

Oral tongue squamous cell carcinoma: recurrent disease is associated with histopathologic risk score and young age.

Purpose: To apply the Brandwein-Gensler et al.'s histopathologic risk score (RS) system and to evaluate its impact on locoregional recurrence and overall survival in a series of cases of oral tongue cancer, along with variables of patient age and margin status.

Methods: Sections of the resection specimens (N = 50) were submitted to a RS assignment of three components: the worst pattern of invasion, lymphocytic infiltration and perineural invasion.

Tumor-host histopathologic variables, stromal myofibroblasts and risk score, are significantly associated with recurrent disease in tongue cancer.

Margin status, a major prognostic parameter in oral cancer, was analyzed vis-à-vis the histopathologic parameters of risk scores and stromal myofibroblasts. Specimens of tongue carcinoma (n = 50) were submitted to a risk score assignment consisting of the worst pattern of invasion, lymphocytic infiltration, and perineural invasion. Frequency of stromal myofibroblasts (alpha-smooth muscle actin stain) was assessed.

Use of alternative medicine in Israeli chronic rhinosinusitis patients.

Objective: The worldwide interest in the use of complementary and alternative medicine (CAM) has been established in multiple surveys. Chronic rhinosinusitis (CRS) is often an unremitting disease with frequent troubling relapses, and despite wide use of endoscopic sinus surgery, conventional medicine may have a smaller contribution than expected. Because of prevalent use of CAM among patients, it is important that physicians acquire basic knowledge of this subject.

Endoscopic sinus surgery for medial orbital subperiosteal abscess in children.

Objective: To present our experience with endoscopically managed medial orbital subperiosteal abscess (MOSA) in children and to compare the results with external drainage of the abscess.

Methods: A retrospective record review was conducted on 22 children with MOSA, of whom 6 underwent drainage by endoscopic sinus surgery (group 1) and 16 underwent external ethmoidectomy (group 2). MOSA was diagnosed by computed tomography of the orbits.

Coexistent chronic lymphocytic leukemia and squamous cell carcinoma of the larynx.

Chronic lymphocytic leukemia (CLL) is the most common lymphoid malignancy among adults in the Western world. Small lymphocytic lymphoma (SLL) represents the lymphomatous presentation of CLL. We describe a case in which a diagnosis of laryngeal CLL/SLL was made in an 82-year-old man who had undergone laryngectomy and neck dissection for the treatment of squamous cell carcinoma of the larynx.

A prospective study of surgical margin status in oral squamous cell carcinoma: a preliminary report.

A protocol was created for prospective margin status evaluation of patients with Oral SCC. Margins are evaluated intra- and post-operatively during three stages. Patients were divided into three groups: group 1 in which one margins were sampled randomly, group 2 with frozen sections taken from the surgical bed and 3 in which they were taken from the tumor specimen itself.

The clinical behavior of isolated sphenoid sinusitis.

Objective: We sought to study the clinical behavior and treatment outcome of isolated sphenoid sinusitis (ISS).

Study Design And Setting: We conducted a retrospective study of patients diagnosed with ISS in a tertiary medical center over 20 years.

Results: Of 72 patients with ISS, 79 percent had acute symptoms, 15 percent had chronic symptoms, and 6 percent had incidental radiological findings.

[Recurrent pleomorphic adenomas of the parotid gland--treatment and outcome].

Epithelial tumors of the parotid gland comprise 3% of head and neck tumors, and 70%-80% of those are benign. Pleomorphic adenoma is the most common tumor of the parotid gland. Recurrence rate of pleomorphic adenomas (RPAs) following superficial parotidectomy was reported to be as high as 4%, sometimes associated with inadequate surgical treatment of the primary tumor.

25-year experience of using a linear stapler in laryngectomy.

Background: Stapler application for pharyngeal closure after total laryngectomy allows for rapid watertight closure without field contamination and for potentially reduced fistula rate.

Methods: One thousand four hundred fifteen patients underwent laryngectomy with linear stapler closure. In 98.

Limited use of complementary and alternative medicine in Israeli head and neck cancer patients.

Hypothesis/objective: The use of complementary or alternative medicine (CAM) is growing among cancer patients. A Medline search failed to reveal any dedicated report of CAM use specifically in patients with head and neck cancer (HNC).

Study Design: Use of CAM was evaluated in a cohort of treated HNC patients.

Quality of life following parotidectomy for malignant and benign disease.

Parotidectomy is performed for benign or malignant tumors and for selected benign inflammatory and autoimmune conditions. Possible associated complications include facial nerve paralysis, pain, loss of sensation, gustatory sweating, and facial scarring. Global quality of life in patients undergoing parotidectomy has not been reported.

Quality of life of well-differentiated thyroid carcinoma patients.

The thyroid gland is the second most common site for malignancy in the head and neck region. Quality of life (QOL) of thyroid cancer patients has not been studied directly. The QOL of long-term thyroid carcinoma patients was investigated.

Coronoidectomy in maxillary swing for reducing the incidence and severity of trismus--a reminder.

Purpose: The maxillary swing approach is a proven method for access to the nasopharynx. However, often, trismus is incurred postoperatively, hampering adequate oral care and follow-up and affecting patients' quality of life.

Case Reports: Coronoidectomy was performed in four patients undergoing maxillary swing.

Preservation of the facial artery in excision of the submandibular salivary gland.

Background: The accepted method for submandibular gland excision traditionally includes ligation of the facial artery (FA) as suggested by a host of surgical atlases. Preservation of the FA may be significant in reconstructive procedures of the head and neck and its ligation may altogether be obviated.

Objective: Prospective feasibility study of FA preservation in submandibular gland excision.