Publications by authors named "Letty Liang"

Background: Premenstrual dysphoric disorder (PMDD) is an understudied, debilitating disorder of women. Given evidence for prefrontal cortical and limbic dysfunction in PMDD, we compared intrinsic connectivity of the executive control network (ECN), default mode network (DMN), and amygdala in women with PMDD vs. controls.

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Article Synopsis
  • Various genetic techniques help trace cell lineage during tissue development, with some focusing on spatial/temporal aspects and others linking gene expression to lineage.
  • The G-TRACE system allows for quick visualization of GAL4 expression patterns, enabling genome-wide expression-based lineage studies conducted by UCLA students and high school scholars.
  • Findings revealed new expression-based lineage patterns and were compiled into the G-TRACE Expression Database (GED), contributing to better student learning outcomes and retention in STEM fields.
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Background: Difficulties in regulating emotions are linked to the core symptoms of premenstrual dysphoric disorder (PMDD). We therefore investigated the neural substrates of emotion-regulation problems in women with PMDD.

Methods: On the basis of self-evaluations over 2 months on the Daily Record of Severity of Problems, eligible participants were assigned to two groups: PMDD and control (18 per group).

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Premenstrual dysphoric disorder (PMDD) is a psychiatric disorder that causes serious impairments in the functioning and quality of life of affected women. Until recently, research efforts were somewhat hampered by the lack of formal diagnostic criteria, which have now been codified as a category in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). Better characterization of deficits in socioemotional functioning caused by PMDD may aid in improving treatment efforts.

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