Publications by authors named "Leticia Ubaldo Rodrigues"
Effects of Heart Rate Reduction With Either Pyridostigmine or Ivabradine in Patients With Heart Failure: A Randomized, Double-Blind Study.
Aline Sterque Villacorta Humberto Villacorta José Antônio Caldas Bernardo Campanário Precht Pilar Barreto Porto Letícia Ubaldo Rodrigues
J Cardiovasc Pharmacol Ther
March 2019
Background: Heart rate (HR) reduction with ivabradine has been proved to reduce hospitalization and death from heart failure (HF). We sought to investigate whether pyridostigmine would effectively reduce HR in patients with chronic HF as compared with ivabradine.
Methods: Twenty-one patients with HF who were in sinus rhythm with a resting HR over 70 bpm, despite optimal medical treatment, were included in a randomized, double-blind study comparing pyridostigmine versus ivabradine.